Cheap Flights from Sikeston (SIK) to Des Moines (DSM)

Popular airlines from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines International Airport (DSM)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Frequently asked questions

How much does a flight from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight or cheap return flight from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM)?
Planning your trip for may help you find better deals, as it's the cheapest month for flights between SIK and DSM. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from SIK to DSM. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM)?
There aren't any daily nonstop flights available from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM). But you can book flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from SIK to DSM?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM)?
Opt for a flight from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM) that leaves before 3 PM to reduce the risk of cancellations and delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM) last-minute?
Booking your flight from SIK to DSM shortly before your trip is generally more expensive. However, if there's some wiggle room with your travel times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a SIK to DSM flight and hotel package?
Opting for a SIK to DSM flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our wide range of hotels and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Sikeston, MO (SIK-Sikeston Memorial Municipal) to Des Moines Intl. Airport (DSM)?
Typically, you're able to reschedule or cancel your SIK to DSM flight. However, additional charges may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like more details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Sikeston Memorial Municipal
Destination airport
Des Moines Intl.
Distance
388 mi

Book with confidence

Book with confidence

Sikeston to Des Moines Flights

The cheapest times to fly from Sikeston to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sikeston to Des Moines are during the month of . You can find some of the cheapest flights from Sikeston to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sikeston to Des Moines

Sunday is one of the best days to book for cheap flights from Sikeston to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sikeston to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sikeston to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sikeston to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sikeston to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Sikeston to Des Moines Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.