$173 Cheap Flights from Tupelo (TUP) to Denver (DEN)

View $173 flight on Tue, Aug 26, 2025Opens in a new window

Popular airlines from Tupelo, MS (TUP-Tupelo Regional) to Denver Intl. Airport (DEN)

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Cheap Flights from Tupelo to Denver (TUP-DEN)

Prices were available within the past 7 days and start at $173 for one-way flights and $346 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Contour Airlines
Wed, Oct 22 - Tue, Oct 28
TUP
Tupelo
DEN
Denver
$346 Roundtrip, found 2 days ago
$346
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Wed, Oct 22 from Tupelo to Denver, returning Tue, Oct 28, priced at $346 found 2 days ago
Contour Airlines
Wed, Oct 22 - Wed, Oct 29
TUP
Tupelo
DEN
Denver
$351 Roundtrip, found 2 days ago
$351
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Wed, Oct 22 from Tupelo to Denver, returning Wed, Oct 29, priced at $351 found 2 days ago
Contour Airlines
Wed, Oct 22 - Sat, Oct 25
TUP
Tupelo
DEN
Denver
$356 Roundtrip, found 2 days ago
$356
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Wed, Oct 22 from Tupelo to Denver, returning Sat, Oct 25, priced at $356 found 2 days ago
Contour Airlines
Tue, Oct 21 - Tue, Oct 28
TUP
Tupelo
DEN
Denver
$360 Roundtrip, found 2 days ago
$360
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Tue, Oct 21 from Tupelo to Denver, returning Tue, Oct 28, priced at $360 found 2 days ago
Contour Airlines
Wed, Oct 22 - Mon, Oct 27
TUP
Tupelo
DEN
Denver
$366 Roundtrip, found 2 days ago
$366
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Wed, Oct 22 from Tupelo to Denver, returning Mon, Oct 27, priced at $366 found 2 days ago
Contour Airlines
Sat, Oct 18 - Mon, Oct 27
TUP
Tupelo
DEN
Denver
$366 Roundtrip, found 2 days ago
$366
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Sat, Oct 18 from Tupelo to Denver, returning Mon, Oct 27, priced at $366 found 2 days ago
Contour Airlines
Tue, Oct 21 - Sat, Oct 25
TUP
Tupelo
DEN
Denver
$370 Roundtrip, found 2 days ago
$370
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Tue, Oct 21 from Tupelo to Denver, returning Sat, Oct 25, priced at $370 found 2 days ago
Contour Airlines
Wed, Oct 22 - Wed, Oct 29
TUP
Tupelo
DEN
Denver
$370 Roundtrip, found 2 days ago
$370
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Wed, Oct 22 from Tupelo to Denver, returning Wed, Oct 29, priced at $370 found 2 days ago
Contour Airlines
Fri, Oct 24 - Tue, Oct 28
TUP
Tupelo
DEN
Denver
$371 Roundtrip, found 2 days ago
$371
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Fri, Oct 24 from Tupelo to Denver, returning Tue, Oct 28, priced at $371 found 2 days ago
Contour Airlines
Sat, Sep 20 - Sun, Sep 28
TUP
Tupelo
DEN
Denver
$375 Roundtrip, found 6 days ago
$375
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Sat, Sep 20 from Tupelo to Denver, returning Sun, Sep 28, priced at $375 found 6 days ago
Flights from Tupelo (TUP) to Denver (DEN)
Origin airport
Tupelo Regional
Destination airport
Denver Intl.
Roundtrip price
$346
Distance
956 mi

Tupelo to Denver Flights

The cheapest times to fly from Tupelo to Denver

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tupelo to Denver are during the month of October. You can find some of the cheapest flights from Tupelo to Denver with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tupelo to Denver

Sunday is one of the best days to book for cheap flights from Tupelo to Denver: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tupelo to Denver

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tupelo to Denver in 2025. You can also book with separate airlines for your outbound and return journeys, from $173 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tupelo to Denver flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tupelo to Denver airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tupelo Regional Airport (TUP) to Denver Intl. Airport (DEN) cost?
Discover the latest flight deals from TUP to DEN by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from TUP to DEN?
The cheapest flights from TUP to DEN are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from TUP to DEN?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from TUP to DEN. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Tupelo Regional Airport (TUP) to Denver Intl. Airport (DEN)?
Nonstop flights from Tupelo Regional Airport (TUP) to Denver Intl. Airport (DEN) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TUP to DEN?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tupelo Regional Airport (TUP) to Denver Intl. Airport (DEN)?
To touch down at Denver Intl. Airport (DEN) without delays, pick a flight that leaves Tupelo Regional Airport (TUP) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tupelo Regional Airport (TUP) to Denver Intl. Airport (DEN) last-minute?
Booking your plane ticket from TUP to DEN just before your getaway is usually more expensive. But if you're flexible with your travel dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a TUP to DEN flight and hotel package?
You'll generally save money by booking a TUP to DEN flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your preferred flights and accommodations, consider adding extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Tupelo Regional Airport (TUP) to Denver Intl. Airport (DEN)?
If you booked your TUP to DEN flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

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*Available to One Key members.