Vacation Rentals in Panama

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Top Cities in Panama

Our top choices for Panama vacation rentals

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (540 reviews)
"Very clean and amazing stay "
United States
Reinaldo
$92 nightly
The price is $102
Apr 20 - Apr 21
Total with taxes and fees
Torres de Alba Hotel & Suites

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.8 out of 10, Good, (279 reviews)
"Great location and good amenities for 1st time travellers Pool view is amazing... "
United States
nikita
$142 nightly
The price is $156
May 3 - May 4
Total with taxes and fees
Boutique Apartments Panama

Downtown Suites

Downtown Suites
3.0 star property
El Tropezón
9.0 out of 10, Wonderful, (105 reviews)
"Good location, nice rooms, great value."
United States
Robert
$66 nightly
The price is $72
May 3 - May 4
Total with taxes and fees
Downtown Suites

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very Good, (87 reviews)
"The stay was wonderful. Highly recommend. Great value. "
Canada
Joseph
$216 nightly
The price is $223
Apr 19 - Apr 20
Total with taxes and fees
Yoo Panamá by Boutique Apartments

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (268 reviews)
"All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. "
United States
Jaime
$120 nightly
The price is $132
Apr 18 - Apr 19
Total with taxes and fees
Arcadia Condo Suites

Villa Alejandro

Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (146 reviews)
"Great location, great room and very responsive hotel."
United States
Tara
$60 nightly
The price is $67
May 18 - May 19
Total with taxes and fees
Villa Alejandro

Surfari Bocas

Surfari Bocas
2.5 star property
Bocas del Toro
9.0 out of 10, Wonderful, (63 reviews)
"Good value and would recommend this place."
Australia
Yvon
$28 nightly
The price is $31
May 3 - May 4
Total with taxes and fees
Surfari Bocas

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (193 reviews)
"Staying and active in rural Boquete Panama is both a treat and a retreat of relaxation."
United States
Jerry
$145 nightly
The price is $161
May 12 - May 13
Total with taxes and fees
La Isabela Suites

El Cielo by Villa Alejandro

El Cielo by Villa Alejandro
3.5 star property
Boquete
9.4 out of 10, Exceptional, (108 reviews)
"Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!"
United States
Lee
$83 nightly
The price is $92
May 13 - May 14
Total with taxes and fees
El Cielo by Villa Alejandro

Villa Noelia

Villa Noelia
2.5 star property
Saboga
7.6 out of 10, Good, (28 reviews)
"There was new staff that were not up to the task for room keeping. We've contacted Cindy, the manager and she was responsive and made sure our stay was comfortable "
Canada
jerry
$113 nightly
The price is $126
May 5 - May 6
Total with taxes and fees
Villa Noelia

Rio Verde by Villa Alejandro

Rio Verde by Villa Alejandro
2.5 star property
Los Naranjos
9.2 out of 10, Wonderful, (102 reviews)
"Loved the grounds and the hot tub room was awesome!"
United States
John
$75 nightly
The price is $82
Apr 21 - Apr 22
Total with taxes and fees
Rio Verde by Villa Alejandro

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (185 reviews)
"Best of the best, as always!"
United States
Rebecca
$128 nightly
The price is $140
Apr 27 - Apr 28
Total with taxes and fees
Las Clementinas

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (184 reviews)
"Would recommend this stay to anyone I know who is visiting Panama. We loved our room and also the check in process was easy! "
United States
Andrena
$178 nightly
The price is $195
Apr 19 - Apr 20
Total with taxes and fees
Boutique Apartments Panamá Coco del Mar

Caribbean Villages Apartments

Caribbean Villages Apartments
3.0 star property
Bocas del Toro
7.6 out of 10, Good, (24 reviews)
"Carlos was very helpful with answering questions and just a kind man. Their is clearly a constant upkeep of the property. Location was good- though there might be an office closer to the boat docks because when we first arrived my map app kept directing me to the wrong place. We really enjoyed our stay. Thank you:)"
United States
Rachelle
$72 nightly
The price is $79
May 4 - May 5
Total with taxes and fees
Caribbean Villages Apartments

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
$183 nightly
The price is $218
Apr 30 - May 1
Total with taxes and fees
Living 73 Panamá by Boutique Apartments

Casa Reina by Villa Alejandro

Casa Reina by Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (19 reviews)
"Mountain views are beautiful, we enjoyed sitting on the deck and observing the mountains and wildlife. I got some really great sunrise pictures. "
United States
Paul
$72 nightly
The price is $80
Apr 28 - Apr 29
Total with taxes and fees
Casa Reina by Villa Alejandro

Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (709 reviews)
"All round top notch"
Canada
Nekesha
$134 nightly
The price is $148
Apr 25 - Apr 26
Total with taxes and fees
Marriott Executive Apartments Panama City, Finisterre

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (88 reviews)
"The staff was absolutely phenomenal! So kind and accommodating even when certain events were out of their control they were still so wonderful!"
United States
Nicole
$122 nightly
The price is $135
Apr 19 - Apr 20
Total with taxes and fees
Casco View Apartments

Casa Love by Wynwood House

Casa Love by Wynwood House
3.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (24 reviews)
"Super "
France
Stephen
$114 nightly
The price is $125
Apr 21 - Apr 22
Total with taxes and fees
Casa Love by Wynwood House

Villas Residences by Playa Caracol Resorts

Villas Residences by Playa Caracol Resorts
3.5 star property
Punta Chame
8.4 out of 10, Very Good, (5 reviews)
"The place was equipped, clean and amazing location, we truly enjoyed and will come back , thank you"
United States
Saro
$156 nightly
The price is $172
Apr 19 - Apr 20
Total with taxes and fees
Villas Residences by Playa Caracol Resorts
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews

Find out more about Panama

Discover your perfect Panama vacation rental with Expedia

How many vacation rentals are available in Panama?


Expedia has plenty of vacation rentals to choose from in and around  Panama, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Panama?


The selection of Panama vacation rentals we have selected for you start as low as $67 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Panama?


Vacation rentals in Panama come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Panama vacation rentals to suit everyone. 


Why should I choose a vacation rental in Panama?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Panama?


Find vacation rentals in Panama by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Panama.  


What amenities are available in a vacation rental in Panama?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Panama vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Panama?   


Everytime is a great time to head to Panama! Staying in a Panama vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Panama. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Panama vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Panama, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Panama vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.  


Explore a world of travel with Expedia