A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Vacation Rentals in Panama

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Dates

November 2026

December 2026

Top cities in Panama

Check prices for these dates

In two weeks

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In three months

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Our top choices for Panama vacation rentals

A modern living room with a large sliding glass door leading to a balcony, a flat-screen TV, and a grey sofa.

1. The Hub by Boutique Apartments

San Francisco

$164 nightly

Nov 17 - Nov 18

Total with taxes and fees

A rooftop pool with a city view, lounge chairs, and a clear sky.

2. Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

Elijah

$127 nightly

Nov 22 - Nov 23

Total with taxes and fees

A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

3. Boutique Apartments Panama

Bella Vista

Kirwan

$125 nightly

Nov 12 - Nov 13

Total with taxes and fees

A rooftop pool with a view of the cityscape, lounge chairs, and potted plants.

4. Casco View Apartments & Rooftop Pool

Santa Ana

$80 nightly

Nov 12 - Nov 13

Total with taxes and fees

A rooftop swimming pool with a city skyline view, surrounded by modern buildings.

5. Loom by Boutique Apartments

San Francisco

$174 nightly

Nov 15 - Nov 16

Total with taxes and fees

An aerial view of a residential area with two swimming pools, surrounded by houses with sloped roofs.

6. Villas The Tides by Playa Caracol Resort

Punta Chame

Tayna

$137 nightly

Nov 11 - Nov 12

Total with taxes and fees

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

7. La Isabela Suites

Casco Viejo

David

$137 nightly

Dec 1 - Dec 2

Total with taxes and fees

A beachside lounge area with sun loungers and a thatched umbrella, palm trees, and a white fence.

8. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Vacamonte

Cynthia

$30 nightly

Nov 11 - Nov 12

Total with taxes and fees

A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

9. Boutique Apartments Panamá Coco del Mar

San Francisco

purabi

$168 nightly

Nov 11 - Nov 12

Total with taxes and fees

A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

10. Pty Loft-style 1br Cincuentenario Bay

San Francisco

Germain

$146 nightly

Nov 12 - Nov 13

Total with taxes and fees

A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

11. Torres de Alba Hotel & Suites

Bella Vista

Patricia

$86 nightly

Dec 11 - Dec 12

Total with taxes and fees

An outdoor seating area with tables and chairs, a view of the beach, and string lights.

12. Refugio Frente al Mar Vista Venao

Veracruz

Joanna

$57 nightly

Nov 14 - Nov 15

Total with taxes and fees

A person seated at a table with a wine bottle and glass, overlooking a garden with a mountain backdrop.

13. Natura Lodge by Villa Alejandro

Bajo Boquete

Silka

$85 nightly

Nov 16 - Nov 17

Total with taxes and fees

A balcony with two white chairs and a small table, overlooking a beach with palm trees and the ocean.

14. Ventanas del Mar by Playa Caracol Resort

Punta Chame

Linda

$100 nightly

Nov 12 - Nov 13

Total with taxes and fees

A swimming pool with a city skyline in the background.

15. Modern Design Apartments near Sortis

Bella Vista

Kareem

$63 nightly

Nov 12 - Nov 13

Total with taxes and fees

A balcony with two chairs, a city skyline, and a view of the ocean.

16. Yoo Panamá by Boutique Apartments

Bella Vista

Yannick

$176 nightly

Nov 18 - Nov 19

Total with taxes and fees

A rooftop pool with lounge chairs, a modern building with a reflective facade, and a clear blue sky.

17. Yoo Panama Luxury Ocean View Apartment

Bella Vista

Mark

$117 nightly

Nov 11 - Nov 12

Total with taxes and fees

An outdoor dining area with a round table and white chairs, surrounded by orange walls and a blue ceiling.

18. Surfari Bocas

Bocas del Toro

Susan Heather

$34 nightly

Nov 11 - Nov 12

Total with taxes and fees

A rooftop pool with lounge chairs and a cityscape view.

19. Marriott Executive Apartments Panama City, Finisterre

Bella Vista

Angela

$118 nightly

Nov 27 - Nov 28

Total with taxes and fees

A modern outdoor swimming pool with a clear view of a tall building in the background.

20. Dovle Residences by HMS-Preferred Member

San Francisco

Patrick

$128 nightly

Nov 18 - Nov 19

Total with taxes and fees

View all properties

Find vacation rentals that suit your style

Top Panama Hotel Reviews

A balcony with wicker chairs and a view of the cityscape.

Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

10/10 Excellent

Theon

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

Hyatt Regency Panama City

Bella Vista

10/10 Excellent

Michael

An outdoor patio with wicker furniture, a stone fireplace, and a view of the garden at dusk.

Hotel Panamonte

Jaramillo

10/10 Excellent

Anonymous traveler

A hot tub on a deck overlooking a lake with boats and a house in the background.

Bocas del Mar Hotel

Boca Chica

10/10 Excellent

William

A view from a balcony with a cityscape in the background, featuring tall buildings and a body of water.

Plaza Paitilla Inn Hotel

San Francisco

10/10 Excellent

Natalie

An indoor swimming pool with a blue tint, surrounded by seating areas and potted plants.

Hotel Ciudad De David

David

10/10 Excellent

leslie

A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

HOTEL VISTA LAGO

La Pena

10/10 Excellent

Sharyn

A historic building with multiple balconies and a statue of a man on horseback.

American Trade Hotel

Casco Viejo

10/10 Excellent

We arrived early from the David airport around 10am and we were just going to drop off our bags and they not only held our bags without question but then also took the time to make sure we had our room early if one was available! (Which there was!)-just be aware during their peak season it may not happen we were just lucky in the off season! The staff is SUPER friendly! The door men were super awesome and were always happy to help us! There will be an umbrella for you to get to your car if it’s...

Ashley

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

Hotel San Felipe

Casco Viejo

10/10 Excellent

Carmen

A modern living room with a sofa, coffee table, and decorative wall art.

Aranjuez Hotel & Suites

David Sur

10/10 Excellent

We stayed at this hotel for the weekend and really enjoyed the weather in Chiriqui. A short 45 minute drive to the Costa Rican border for shopping at the FreeZone and also same amount of time to visit Boquete. If you are visiting Boquete, coffee tours is a must because after tasting coffee in Boquete you will never taste any other coffee but coffee from Boquete! Be carefull if you are driving to the border or on the high way around the area as there are lots of road stops and random checks. ...

Mohammad

A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

Novotel Panama City

Bella Vista

10/10 Excellent

Blaise

A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.

The Executive Hotel

Bella Vista

10/10 Excellent

Debra

A unique building with large cylindrical structures, a wooden deck, and outdoor seating.

ONDA Boquete

Boquete

10/10 Excellent

Valerie

A multi-story building with balconies, arched windows, and decorative railings.

Central Hotel Panama Casco Viejo

Casco Viejo

10/10 Excellent

Lourdes

A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.

Gran Evenia Panama

Bella Vista

10/10 Excellent

Gia

Frequently Asked Questions

How many vacation rentals are available in Panama?

Expedia has plenty of vacation rentals to choose from in and around Panama, so you’re guaranteed to find the right one for you.

How much is a vacation rental in Panama?

The selection of Panama vacation rentals we have selected for you start as low as $63 per night. Entering your travel dates in the search wizard you might find even better deals!

What type of vacation rental can I get in Panama?

Vacation rentals in Panama come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Panama vacation rentals to suit everyone.

Why should I choose a vacation rental in Panama?

Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.

How do I find the best deal on a vacation rental in Panama?

Find vacation rentals in Panama by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Panama.

What amenities are available in a vacation rental in Panama?

The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Panama vacation rentals designed to suit every budget and trip type.

When is the best time to stay in a vacation rental in Panama?

Everytime is a great time to head to Panama! Staying in a Panama vacation rentals you will always find lots going on to keep you entertained.

Why book a vacation rental with Expedia?

Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Panama. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Panama vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Panama, you can save even more.

Can I cancel my vacation rental through Expedia?

Yes, you can cancel or change your Panama vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.

Vacation Rentals in Panama

Top cities in Panama

Panama City

Check prices for these dates

Our top choices for Panama vacation rentals

1. The Hub by Boutique Apartments

2. Corporate Stays Arcadia | Executive Furnished Apartments

3. Boutique Apartments Panama

4. Casco View Apartments & Rooftop Pool

5. Loom by Boutique Apartments

6. Villas The Tides by Playa Caracol Resort

7. La Isabela Suites

8. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

9. Boutique Apartments Panamá Coco del Mar

10. Pty Loft-style 1br Cincuentenario Bay

11. Torres de Alba Hotel & Suites

12. Refugio Frente al Mar Vista Venao

13. Natura Lodge by Villa Alejandro

14. Ventanas del Mar by Playa Caracol Resort

15. Modern Design Apartments near Sortis

16. Yoo Panamá by Boutique Apartments

17. Yoo Panama Luxury Ocean View Apartment

18. Surfari Bocas

19. Marriott Executive Apartments Panama City, Finisterre

20. Dovle Residences by HMS-Preferred Member

Find vacation rentals that suit your style

Top Panama Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent

Frequently Asked Questions

How many vacation rentals are available in Panama?

How much is a vacation rental in Panama?

What type of vacation rental can I get in Panama?

Why should I choose a vacation rental in Panama?

How do I find the best deal on a vacation rental in Panama?

What amenities are available in a vacation rental in Panama?

When is the best time to stay in a vacation rental in Panama?

Why book a vacation rental with Expedia?

Can I cancel my vacation rental through Expedia?

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