Otay Mesa, CA
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Stand up Paddle Board Lesson on The San Diego Bay
$25
per adult
100% of travellers recommend
From Tijuana: Valle de Guadalupe Private Winery Tour
$143
per adult
Tijuana: Guided City Tour with Local Food and Beer Tasting
$114
per adult
Tijuana Walking Street Food Tour for Foodies
$79
per adult
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
$99
per adult
Otay Mesa Hotel Deals
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
$285 nightly
The price is $328 total per night from Aug 30 to Aug 31
$328 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
$180 nightly
The price is $208 total per night from Aug 17 to Aug 18
$208 total
Aug 17 - Aug 18
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,261 reviews)
"I was going there last month and I had everything perfect I recommend it"
Reviewed on Jul 31, 2026
Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave Coronado CA
$558 nightly
The price is $619 total per night from Aug 18 to Aug 19
$619 total
Aug 18 - Aug 19
Total with taxes and fees
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
$229 nightly
The price is $265 total per night from Aug 12 to Aug 13
$265 total
Aug 12 - Aug 13
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
$248 nightly
The price is $285 total per night from Aug 16 to Aug 17
$285 total
Aug 16 - Aug 17
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,404 reviews)
"All was excellent"
Reviewed on Jul 31, 2026
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
$191 nightly
The price is $220 total per night from Aug 23 to Aug 24
$220 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,618 reviews)
"This is a fabulous property that you can tell is well managed. Spotless, friendly employees, well maintained and very comfortable rooms Highly recommend"
Reviewed on Jul 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Riviera Shores Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
Otay Mesa, CA
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