Otay Mesa, CA
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Stand up Paddle Board Lesson on The San Diego Bay
$25
per adult
100% of travellers recommend
From Tijuana: Valle de Guadalupe Private Winery Tour
$122
per adult
Tijuana: Guided City Tour with Local Food and Beer Tasting
$92
per adult
Tijuana Walking Street Food Tour with Wild Foodie Tours
$79
per adult
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
$99
per adult
Otay Mesa Hotel Deals
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
$269 nightly
The price is $309 total per night from Aug 30 to Aug 31
$309 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,767 reviews)
"Great spot for families, the pool was perfect for relaxing and the gym is well equipped. Grounds were beautiful and lots of wildlife around. Clean rooms and ice cold AC. The parking charge was a surprise to us."
Reviewed on Aug 2, 2026
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
$259 nightly
The price is $300 total per night from Aug 27 to Aug 28
$300 total
Aug 27 - Aug 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,775 reviews)
"Love it!"
Reviewed on Aug 2, 2026
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
$167 nightly
The price is $194 total per night from Aug 5 to Aug 6
$194 total
Aug 5 - Aug 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Loews Coronado Bay Resort
4000 Coronado Bay Rd Coronado CA
$307 nightly
The price is $341 total per night from Sep 1 to Sep 2
$341 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this beach hotel in Coronado. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place San Diego CA
$151 nightly
The price is $174 total per night from Aug 31 to Sep 1
$174 total
Aug 31 - Sep 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (2,852 reviews)
"There were 5 of us staying in a 2 room suite. Needless to say we needed a lot of towels and with in minutes they were delivered to our room. I would stay there again. The one thing that I didn’t like was paying for parking"
Reviewed on Aug 2, 2026
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
$234 nightly
The price is $269 total per night from Sep 1 to Sep 2
$269 total
Sep 1 - Sep 2
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,413 reviews)
"M"
Reviewed on Aug 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Riviera Shores Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
Otay Mesa, CA
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