Find hotels near San Diego Santa Fe Depot, San Diego from $60

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Our top choices for San Diego Santa Fe Depot hotels

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 1.1 mi from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (783)
"Good place to stay "
United States
sai
$52 nightly
The price is $60
Dec 16 - Dec 17
Total with taxes and fees
Stay Classy Hostel

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
1.2 mi from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (104)
"would definitely go back and stay there again "
United States
Kounwick
$166 nightly
The price is $187
Dec 18 - Dec 19
Total with taxes and fees
City24 Hotel Little Italy Mission Hills

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
0.7 mi from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1001)
"I like the Hotel!!"
United States
Karla
$135 nightly
The price is $157
Dec 24 - Dec 25
Total with taxes and fees
Marriott Vacation Club®, San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 0.7 mi from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
$137 nightly
The price is $159
Dec 26 - Dec 27
Total with taxes and fees
Staypineapple, Hotel Z, Gaslamp San Diego

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
0.1 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1000)
"Great place to stay"
United States
Kimberly
$188 nightly
The price is $218
Jan 5 - Jan 6, 2026
Total with taxes and fees
Springhill Suites San Diego Downtown/Bayfront

InterContinental San Diego by IHG

InterContinental San Diego by IHG
4.0 star property
0.2 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1113)
"Excellent location prior to a cruise."
Canada
Joan
$265 nightly
The price is $307
Jan 4 - Jan 5, 2026
Total with taxes and fees
InterContinental San Diego by IHG

Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
0.2 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (637)
"Really enjoyed the breakfast! Location was great and overall great stay! Hope to be back sometime in the next year coming up! "
United States
Omar
$208 nightly
The price is $242
Jan 4 - Jan 5, 2026
Total with taxes and fees
Residence Inn by Marriott San Diego Downtown/Bayfront

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 0.5 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1941)
"Great hotel"
United States
Farzana
$204 nightly
The price is $237
Dec 18 - Dec 19
Total with taxes and fees
Marriott Marquis San Diego Marina

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Gaslamp Quarter, 0.5 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (617)
"Welcome drink and breakfast were a nice treat."
United States
Mona
$139 nightly
The price is $161
Dec 17 - Dec 18
Total with taxes and fees
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 0.6 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (535)
"Never had this much fun in time of a simple night stay! Great accessibility as well. "
United States
Dulce de la
$94 nightly
The price is $107
Dec 14 - Dec 15
Total with taxes and fees
Gaslamp Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top San Diego Santa Fe Depot Hotel Reviews

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 829 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Hard Rock Hotel San Diego is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an outdoor pool. It's located just a short 0.8 mi (1.3 km) from San Diego Santa Fe Depot. Other good options close by include Manchester Grand Hyatt San Diego and The DEXTRO Little Italy, BW Premier Collection.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 829 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Star of India, and Whaley House Museum are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Old Globe Theater if you're interested in local theater.

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