Find hotels near San Diego Santa Fe Depot, San Diego from $60

Start date: Check-in selected.
End date: Check-out

Check prices for these dates

Tonight
Sep 2 - Sep 3
Tomorrow
Sep 3 - Sep 4
This weekend
Sep 5 - Sep 7
Next weekend
Sep 12 - Sep 14

Filter by

Guest rating
Guest rating
Star rating

Discover hotels close to San Diego Santa Fe Depot with room rates, reviews, and availability. Most hotels are fully refundable.

Kasa Little Italy San Diego
Outdoor pool

Kasa Little Italy San Diego

4.5 star property
9.6 out of 10, Exceptional, (300)
"Great location with city views and amazing amenities! "
$208 nightly
The price is $238
Sep 15 - Sep 16
Total with taxes and fees
Kasa Little Italy San Diego
Springhill Suites San Diego Downtown/Bayfront
Meeting facility

Springhill Suites San Diego Downtown/Bayfront

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Great place to stay!"
$224 nightly
The price is $260
Sep 21 - Sep 22
Total with taxes and fees
Springhill Suites San Diego Downtown/Bayfront
InterContinental San Diego by IHG
Exterior

InterContinental San Diego by IHG

4.0 star property
9.2 out of 10, Wonderful, (1034)
"Excellent location "
$313 nightly
The price is $363
Sep 29 - Sep 30
Total with taxes and fees
InterContinental San Diego by IHG
Residence Inn by Marriott San Diego Downtown/Bayfront
Meeting facility

Residence Inn by Marriott San Diego Downtown/Bayfront

3.0 star property
9.2 out of 10, Wonderful, (615)
"Very clean and accessible hotel."
$249 nightly
The price is $289
Sep 4 - Sep 5
Total with taxes and fees
Residence Inn by Marriott San Diego Downtown/Bayfront
Marriott Marquis San Diego Marina
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)

Marriott Marquis San Diego Marina

4.0 star property
9.2 out of 10, Wonderful, (1847)
"Our stay was great. Can’t wait to go back."
$285 nightly
The price is $331
Sep 11 - Sep 12
Total with taxes and fees
Marriott Marquis San Diego Marina
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Terrace/patio

The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

4.0 star property
9.0 out of 10, Wonderful, (1000)
"Great place to stay at; very well located and in great condition;"
$193 nightly
The price is $223
Sep 21 - Sep 22
Total with taxes and fees
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Hotel Republic San Diego, Autograph Collection
2 bars/lounges, rooftop bar

Hotel Republic San Diego, Autograph Collection

4.0 star property
9.0 out of 10, Wonderful, (1111)
"Nice place to stay"
$196 nightly
The price is $228
Sep 20 - Sep 21
Total with taxes and fees
Hotel Republic San Diego, Autograph Collection
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillowtop beds, desk, blackout drapes

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1000)
"Great location | center of action | nearby restaurants and bars | great service from staff | excellent room | great amenities"
$179 nightly
The price is $207
Sep 21 - Sep 22
Total with taxes and fees
Staypineapple, Hotel Z, Gaslamp San Diego
Stay Classy Hostel
1 bedroom, memory foam beds, blackout drapes, iron/ironing board

Stay Classy Hostel

2.0 star property
9.6 out of 10, Exceptional, (696)
"Awesome place.. clean and friendly staff."
$52 nightly
The price is $60
Sep 7 - Sep 8
Total with taxes and fees
Stay Classy Hostel
Embassy Suites by Hilton San Diego Bay Downtown
Lobby

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
9.0 out of 10, Wonderful, (1416)
"Great location and breakfast, would stay here again."
$209 nightly
The price is $242
Sep 21 - Sep 22
Total with taxes and fees
Embassy Suites by Hilton San Diego Bay Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top San Diego Santa Fe Depot Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 759 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Adjacent to San Diego Santa Fe Depot, Wyndham San Diego Bayside is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and an outdoor pool. Other good options close by include The DEXTRO Little Italy, BW Premier Collection and Manchester Grand Hyatt San Diego.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 759 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Star of India, and Our Lady of the Rosary Catholic Church are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Humphreys Concerts by the Bay if you're interested in local theater.