Find hotels near San Diego Santa Fe Depot, San Diego from $60

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Our top choices for San Diego Santa Fe Depot hotels

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
0.1 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1000)
"Great place to stay"
United States
Kimberly
$188 nightly
The price is $218
Jan 5 - Jan 6, 2026
Total with taxes and fees
Springhill Suites San Diego Downtown/Bayfront

InterContinental San Diego by IHG

InterContinental San Diego by IHG
4.0 star property
0.2 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1114)
"Room was great, the amenities great, overall very nice. "
United States
Crystal
$299 nightly
The price is $347
Dec 15 - Dec 16
Total with taxes and fees
InterContinental San Diego by IHG

Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
0.2 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (637)
"Really enjoyed the breakfast! Location was great and overall great stay! Hope to be back sometime in the next year coming up! "
United States
Omar
$218 nightly
The price is $253
Dec 21 - Dec 22
Total with taxes and fees
Residence Inn by Marriott San Diego Downtown/Bayfront

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
0.7 mi from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1001)
"I like the Hotel!!"
United States
Karla
$135 nightly
The price is $157
Jan 4 - Jan 5, 2026
Total with taxes and fees
Marriott Vacation Club®, San Diego

The Guild Hotel, San Diego Downtown, a Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Tribute Portfolio Hotel
4.0 star property
< 0.1 mi from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1061)
"Staff was friendly and accommodating, rooms were good size and clean "
United States
Alan
$131 nightly
The price is $152
Dec 16 - Dec 17
Total with taxes and fees
The Guild Hotel, San Diego Downtown, a Tribute Portfolio Hotel

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
0.3 mi from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1000)
"Great staff and location."
United States
Lisa
$122 nightly
The price is $141
Dec 18 - Dec 19
Total with taxes and fees
Best Western Plus Bayside Inn

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 0.7 mi from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
$137 nightly
The price is $159
Dec 26 - Dec 27
Total with taxes and fees
Staypineapple, Hotel Z, Gaslamp San Diego

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 0.5 mi from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1942)
"Great hotel"
United States
Farzana
$204 nightly
The price is $237
Dec 18 - Dec 19
Total with taxes and fees
Marriott Marquis San Diego Marina

Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection
4.0 star property
0.2 mi from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1182)
"Amazing stay "
United States
Aaron
$187 nightly
The price is $217
Dec 18 - Dec 19
Total with taxes and fees
Hotel Republic San Diego, Autograph Collection

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 1.1 mi from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (783)
"Good place to stay "
United States
sai
$52 nightly
The price is $60
Dec 18 - Dec 19
Total with taxes and fees
Stay Classy Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top San Diego Santa Fe Depot Hotel Reviews

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 829 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Hard Rock Hotel San Diego is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an outdoor pool. It's located just a short 0.8 mi (1.3 km) from San Diego Santa Fe Depot. Other good options close by include Manchester Grand Hyatt San Diego and The DEXTRO Little Italy, BW Premier Collection.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 829 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Star of India, and Whaley House Museum are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Old Globe Theater if you're interested in local theater.

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