$271 Cheap Flights from Wilmington (ILM) to Des Moines (DSM)

View $271 flight on Sun, Dec 21, 2025Opens in a new window

Popular airlines from Wilmington Intl. Airport (ILM) to Des Moines International Airport (DSM)

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Cheap Flights from Wilmington to Des Moines (ILM-DSM)

Prices were available within the past 7 days and start at $271 for one-way flights and $259 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Jan 21 - Wed, Feb 4
ILM
Wilmington
DSM
Des Moines
$259 Roundtrip, found 4 hours ago
$259
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Jan 21 from Wilmington to Des Moines, returning Wed, Feb 4, priced at $259 found 4 hours ago
American Airlines
Sat, Jan 17 - Sun, Jan 18
ILM
Wilmington
DSM
Des Moines
$264 Roundtrip, found 3 days ago
$264
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jan 17 from Wilmington to Des Moines, returning Sun, Jan 18, priced at $264 found 3 days ago
Delta
Sat, Jan 24 - Tue, Feb 3
ILM
Wilmington
DSM
Des Moines
$269 Roundtrip, found 4 hours ago
$269
Roundtrip
found 4 hours ago
Select Delta flight, departing Sat, Jan 24 from Wilmington to Des Moines, returning Tue, Feb 3, priced at $269 found 4 hours ago
American Airlines
Thu, Dec 25 - Thu, Jan 1
ILM
Wilmington
DSM
Des Moines
$289 Roundtrip, found 2 days ago
$289
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Dec 25 from Wilmington to Des Moines, returning Thu, Jan 1, priced at $289 found 2 days ago
Delta
Tue, Nov 18 - Thu, Nov 27
ILM
Wilmington
DSM
Des Moines
$294 Roundtrip, found 6 days ago
$294
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Nov 18 from Wilmington to Des Moines, returning Thu, Nov 27, priced at $294 found 6 days ago
American Airlines
Sat, Jan 17 - Sun, Jan 18
ILM
Wilmington
DSM
Des Moines
$294 Roundtrip, found 3 days ago
$294
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jan 17 from Wilmington to Des Moines, returning Sun, Jan 18, priced at $294 found 3 days ago
Delta
Sat, Feb 14 - Mon, Feb 23
ILM
Wilmington
DSM
Des Moines
$299 Roundtrip, found 6 days ago
$299
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Feb 14 from Wilmington to Des Moines, returning Mon, Feb 23, priced at $299 found 6 days ago
Delta
Tue, Jan 20 - Wed, Feb 4
ILM
Wilmington
DSM
Des Moines
$319 Roundtrip, found 4 hours ago
$319
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Jan 20 from Wilmington to Des Moines, returning Wed, Feb 4, priced at $319 found 4 hours ago
American Airlines
Sat, Jan 17 - Sun, Jan 18
ILM
Wilmington
DSM
Des Moines
$321 Roundtrip, found 3 days ago
$321
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jan 17 from Wilmington to Des Moines, returning Sun, Jan 18, priced at $321 found 3 days ago
United
Sun, Nov 23 - Sat, Dec 6
ILM
Wilmington
DSM
Des Moines
$339 Roundtrip, found 4 days ago
$339
Roundtrip
found 4 days ago
Select United flight, departing Sun, Nov 23 from Wilmington to Des Moines, returning Sat, Dec 6, priced at $339 found 4 days ago

Find the cheapest month to fly from Wilmington (ILM) to Des Moines (DSM)

February is typically the cheapest month to fly

From $228 - $540 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $294
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $294

Frequently asked questions

How much does a flight from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight from $271 or cheap return flight from $259 from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM)?
Planning your getaway for January can help you save, as it's the cheapest month for flights between ILM and DSM. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from ILM to DSM. Then, sort your results by "Price (lowest to highest)" to snag the best deal available.
How many flights per day from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM)?
Nonstop flights from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from ILM to DSM?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM)?
Book a flight from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM) last-minute?
Holding off until just before your departure to book a flight from ILM to DSM generally means paying more. While you may find some last-minute discounts, they aren't always guaranteed. Be flexible with your itinerary to boost your chances of landing a bargain.
Is it cheaper to book an ILM to DSM flight and hotel package?
Compared with arranging flights and hotels separately, booking an ILM to DSM flight and hotel package with Expedia could lead to significant savings. What's more, having it all in one place takes the hassle out of travel planning. Just secure your flights and choose from our extensive range of stays, then customize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Wilmington Intl. Airport (ILM) to Des Moines Intl. Airport (DSM)?
It's usually possible to reschedule or cancel your ILM to DSM flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Wilmington Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$258
Distance
991 mi

Book with confidence

Wilmington to Des Moines Flights

The cheapest times to fly from Wilmington to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Wilmington to Des Moines are during the month of January. You can find some of the cheapest flights from Wilmington to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Wilmington to Des Moines

Sunday is one of the best days to book for cheap flights from Wilmington to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Wilmington to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Wilmington to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $271 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Wilmington to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Wilmington to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Wilmington to Des Moines Flights

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*Available to One Key members.