$852 Cheap Flights from Johannesburg (JNB) to Des Moines (DSM)

View $852 flight on Sun, Sep 21, 2025Opens in a new window

Popular airlines from O.R. Tambo Intl. Airport (JNB) to Des Moines International Airport (DSM)

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Cheap Flights from Johannesburg to Des Moines (JNB-DSM)

Prices were available within the past 7 days and start at $852 for one-way flights and $1,081 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Virgin Atlantic
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,081 Roundtrip, found 23 hours ago
$1,081
Roundtrip
found 23 hours ago
Select Virgin Atlantic flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,081 found 23 hours ago
Virgin Atlantic
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,221 Roundtrip, found 23 hours ago
$1,221
Roundtrip
found 23 hours ago
Select Virgin Atlantic flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,221 found 23 hours ago
United
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,225 Roundtrip, found 23 hours ago
$1,225
Roundtrip
found 23 hours ago
Select United flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,225 found 23 hours ago
Delta
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,258 Roundtrip, found 23 hours ago
$1,258
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,258 found 23 hours ago
Delta
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,313 Roundtrip, found 23 hours ago
$1,313
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,313 found 23 hours ago
Delta
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,320 Roundtrip, found 23 hours ago
$1,320
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,320 found 23 hours ago
American Airlines
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,339 Roundtrip, found 23 hours ago
$1,339
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,339 found 23 hours ago
United
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,346 Roundtrip, found 23 hours ago
$1,346
Roundtrip
found 23 hours ago
Select United flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,346 found 23 hours ago
American Airlines
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,349 Roundtrip, found 23 hours ago
$1,349
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,349 found 23 hours ago
Air France
Wed, Oct 1 - Fri, Oct 17
JNB
Johannesburg
DSM
Des Moines
$1,355 Roundtrip, found 23 hours ago
$1,355
Roundtrip
found 23 hours ago
Select Air France flight, departing Wed, Oct 1 from Johannesburg to Des Moines, returning Fri, Oct 17, priced at $1,355 found 23 hours ago
Flights from Johannesburg (JNB) to Des Moines (DSM)
Origin airport
O.R. Tambo Intl.
Destination airport
Des Moines Intl.
Airlines serving
Air France, American Airlines, British Airways, Delta, KLM, Lufthansa, Qatar Airways, United, Virgin Atlantic
Roundtrip price
$1,081
Distance
9003 mi

Johannesburg to Des Moines Flights

The cheapest times to fly from Johannesburg to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Johannesburg to Des Moines are during the month of October. You can find some of the cheapest flights from Johannesburg to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Johannesburg to Des Moines

Sunday is one of the best days to book for cheap flights from Johannesburg to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Johannesburg to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Johannesburg to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $852 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Johannesburg to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Johannesburg to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from O.R. Tambo Intl. Airport (JNB) to Des Moines Intl. Airport (DSM) cost?
Discover the latest flight deals from JNB to DSM by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from JNB to DSM?
The cheapest flights from JNB to DSM are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from JNB to DSM?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from JNB to DSM. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from O.R. Tambo Intl. Airport (JNB) to Des Moines Intl. Airport (DSM)?
There aren't any daily nonstop flights available from O.R. Tambo Intl. Airport (JNB) to Des Moines Intl. Airport (DSM). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from JNB to DSM?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can vary depending on various factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from O.R. Tambo Intl. Airport (JNB) to Des Moines Intl. Airport (DSM)?
To arrive at Des Moines Intl. Airport (DSM) on time, book a flight that takes off from O.R. Tambo Intl. Airport (JNB) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from O.R. Tambo Intl. Airport (JNB) to Des Moines Intl. Airport (DSM) last-minute?
Booking your plane ticket from JNB to DSM right before your getaway is usually more expensive. But if you're flexible with your departure times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a JNB to DSM flight and hotel package?
You'll generally save money by booking a JNB to DSM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After choosing your preferred accommodations and flights, consider adding extras such as activities, tours and car rentals.
Can I cancel or change the date of my flight from O.R. Tambo Intl. Airport (JNB) to Des Moines Intl. Airport (DSM)?
Typically, it's possible to reschedule or cancel your JNB to DSM flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.