$100 Cheap Flights from Milwaukee (MKE) to Des Moines (DSM)

View $100 flight on Thu, Dec 25, 2025Opens in a new window

Popular airlines from General Mitchell Intl. Airport (MKE) to Des Moines International Airport (DSM)

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Cheap Flights from Milwaukee to Des Moines (MKE-DSM)

Prices were available within the past 7 days and start at $100 for one-way flights and $209 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Nov 24 - Thu, Nov 27
MKE
Milwaukee
DSM
Des Moines
$209 Roundtrip, found 4 days ago
$209
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Nov 24 from Milwaukee to Des Moines, returning Thu, Nov 27, priced at $209 found 4 days ago
United
Mon, Nov 24 - Thu, Nov 27
MKE
Milwaukee
DSM
Des Moines
$212 Roundtrip, found 4 days ago
$212
Roundtrip
found 4 days ago
Select United flight, departing Mon, Nov 24 from Milwaukee to Des Moines, returning Thu, Nov 27, priced at $212 found 4 days ago
Delta
Sat, Nov 15 - Sat, Dec 6
MKE
Milwaukee
DSM
Des Moines
$213 Roundtrip, found 6 days ago
$213
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Nov 15 from Milwaukee to Des Moines, returning Sat, Dec 6, priced at $213 found 6 days ago
United
Mon, Nov 24 - Thu, Nov 27
MKE
Milwaukee
DSM
Des Moines
$214 Roundtrip, found 4 days ago
$214
Roundtrip
found 4 days ago
Select United flight, departing Mon, Nov 24 from Milwaukee to Des Moines, returning Thu, Nov 27, priced at $214 found 4 days ago
Delta
Sat, Feb 7 - Sat, Feb 21
MKE
Milwaukee
DSM
Des Moines
$228 Roundtrip, found 5 days ago
$228
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Feb 7 from Milwaukee to Des Moines, returning Sat, Feb 21, priced at $228 found 5 days ago
Delta
Wed, Nov 19 - Mon, Nov 24
MKE
Milwaukee
DSM
Des Moines
$235 Roundtrip, found 1 day ago
$235
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Nov 19 from Milwaukee to Des Moines, returning Mon, Nov 24, priced at $235 found 1 day ago
Delta
Thu, Jan 1 - Sun, Jan 11
MKE
Milwaukee
DSM
Des Moines
$236 Roundtrip, found 6 days ago
$236
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Jan 1 from Milwaukee to Des Moines, returning Sun, Jan 11, priced at $236 found 6 days ago
American Airlines
Tue, Dec 16 - Thu, Dec 18
MKE
Milwaukee
DSM
Des Moines
$238 Roundtrip, found 6 days ago
$238
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Dec 16 from Milwaukee to Des Moines, returning Thu, Dec 18, priced at $238 found 6 days ago
Southwest Airlines
Tue, Dec 16 - Thu, Dec 18
MKE
Milwaukee
DSM
Des Moines
$240 Roundtrip, found 6 days ago
$240
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Dec 16 from Milwaukee to Des Moines, returning Thu, Dec 18, priced at $240 found 6 days ago
American Airlines
Mon, Nov 24 - Thu, Nov 27
MKE
Milwaukee
DSM
Des Moines
$242 Roundtrip, found 4 days ago
$242
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Nov 24 from Milwaukee to Des Moines, returning Thu, Nov 27, priced at $242 found 4 days ago

Find the cheapest month to fly from Milwaukee (MKE) to Des Moines (DSM)

September is typically the cheapest month to fly

From $156 - $516 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $323
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $323

Frequently asked questions

How much does a flight from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight from $100 or cheap return flight from $209 from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM)?
November is the least expensive month to fly from MKE to DSM. Timing your trip outside of the busy season is often the key to better flight prices.
What is the cheapest airline that flies from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM)?
To find the cheapest airline that'll fly you from MKE to DSM, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM)?
Nonstop flights from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MKE to DSM?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM)?
To touch down at Des Moines Intl. Airport (DSM) on time, book a flight that leaves General Mitchell Intl. Airport (MKE) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM) last-minute?
Booking your ticket from MKE to DSM shortly before your journey is typically more expensive. But if there's some wiggle room with your travel dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a MKE to DSM flight and hotel package?
Booking a MKE to DSM flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our impressive range of hotels and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from General Mitchell Intl. Airport (MKE) to Des Moines Intl. Airport (DSM)?
In most cases, you can cancel or reschedule your MKE to DSM flight. However, additional charges may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you need more details, head to our Customer Service portal.

Travel information

Origin airport
General Mitchell Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$208
Distance
309 mi

Book with confidence

Milwaukee to Des Moines Flights

The cheapest times to fly from Milwaukee to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Milwaukee to Des Moines are during the month of November. You can find some of the cheapest flights from Milwaukee to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Milwaukee to Des Moines

Sunday is one of the best days to book for cheap flights from Milwaukee to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Milwaukee to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Milwaukee to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Milwaukee to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Milwaukee to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Milwaukee to Des Moines Flights

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*Available to One Key members.