$91 Cheap Flights from Buffalo (BUF) to St. Louis (STL)

View $91 flight on Thu, Apr 9, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to St. Louis Lambert Intl. Airport (STL)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Buffalo to St. Louis (BUF-STL)

Prices were available within the past 7 days and start at $91 for one-way flights and $170 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Fri, Apr 10 - Thu, Apr 23
BUF
Buffalo
STL
St. Louis
$170 Roundtrip, found 3 days ago
$170
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Apr 10 from Buffalo to St. Louis, returning Thu, Apr 23, priced at $170 found 3 days ago
Frontier Airlines
Wed, Apr 8 - Thu, Apr 23
BUF
Buffalo
STL
St. Louis
$191 Roundtrip, found 3 days ago
$191
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Apr 8 from Buffalo to St. Louis, returning Thu, Apr 23, priced at $191 found 3 days ago
Frontier Airlines
Mon, Apr 6 - Thu, Apr 23
BUF
Buffalo
STL
St. Louis
$205 Roundtrip, found 3 days ago
$205
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Apr 6 from Buffalo to St. Louis, returning Thu, Apr 23, priced at $205 found 3 days ago
Frontier Airlines
Fri, May 1 - Fri, May 8
BUF
Buffalo
STL
St. Louis
$212 Roundtrip, found 3 days ago
$212
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, May 1 from Buffalo to St. Louis, returning Fri, May 8, priced at $212 found 3 days ago
Frontier Airlines
Sat, Apr 18 - Thu, Apr 23
BUF
Buffalo
STL
St. Louis
$225 Roundtrip, found 3 days ago
$225
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Apr 18 from Buffalo to St. Louis, returning Thu, Apr 23, priced at $225 found 3 days ago
Frontier Airlines
Thu, May 21 - Thu, Jun 4
BUF
Buffalo
STL
St. Louis
$226 Roundtrip, found 5 days ago
$226
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Thu, May 21 from Buffalo to St. Louis, returning Thu, Jun 4, priced at $226 found 5 days ago
American Airlines
Tue, Mar 31 - Wed, Apr 1
BUF
Buffalo
STL
St. Louis
$257 Roundtrip, found 5 days ago
$257
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Mar 31 from Buffalo to St. Louis, returning Wed, Apr 1, priced at $257 found 5 days ago
United
Tue, Apr 14 - Wed, Apr 15
BUF
Buffalo
STL
St. Louis
$277 Roundtrip, found 7 hours ago
$277
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Apr 14 from Buffalo to St. Louis, returning Wed, Apr 15, priced at $277 found 7 hours ago
Southwest Airlines
Tue, Apr 14 - Wed, Apr 15
BUF
Buffalo
STL
St. Louis
$277 Roundtrip, found 7 hours ago
$277
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Tue, Apr 14 from Buffalo to St. Louis, returning Wed, Apr 15, priced at $277 found 7 hours ago
Delta
Tue, Apr 14 - Wed, Apr 15
BUF
Buffalo
STL
St. Louis
$311 Roundtrip, found 7 hours ago
$311
Roundtrip
found 7 hours ago
Select Delta flight, departing Tue, Apr 14 from Buffalo to St. Louis, returning Wed, Apr 15, priced at $311 found 7 hours ago

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $250
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $250

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find cheap one-way flights from $91 and cheap return flights from $170 Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) with Expedia. One-way flights generally range between $149 and $656, and roundtrip flights usually range from $280 to $1050. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
September is the cheapest month to fly from Buffalo (BUF) to St. Louis (STL), with average round-trip fares around $309. This is about 23% lower than the average price throughout the year, as September often has less travel activity after the summer. Other cheap months to consider are May and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter BUF to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Buffalo Niagara Intl. (BUF) to Lambert-St. Louis Intl. (STL), with round-trip tickets starting from around $168. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best times to fly from Buffalo, NY (BUF) to St. Louis, MO (STL) are August and September. In September, you can find return flights for about $309, making it a cost-effective option. These months are popular for travel, providing a good mix of price and availability, according to booking data from the past year.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from BUF to STL. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from Buffalo Niagara International Airport (BUF) to Lambert-St. Louis International Airport (STL) are in the early morning, from 6am to 9am. About 32% of passengers prefer this time window. Many major carriers, including Southwest Airlines, American Airlines, and Delta, offer flights during this window. This timing works well because it allows you to start your day early and arrive in St. Louis with plenty of time to explore.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
A flight from BUF to STL with a layover takes around 6 hours 30 minutes, with the route covering approximately 673 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You can fly first class between BUF and STL. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from Buffalo Niagara Intl. (BUF)?
From Buffalo Niagara Intl. (BUF), you can fly into Lambert-St. Louis Intl. (STL) to reach St. Louis. Some flights may connect through major hubs like Baltimore Washington Intl. Thurgood Marshall (BWI), Washington Dulles Intl. (IAD), Midway Intl. (MDW) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) St Louis Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$170
Distance
672 mi

Book with confidence

Buffalo to St. Louis Flights

The cheapest times to fly from Buffalo to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to St. Louis are during the month of April. You can find some of the cheapest flights from Buffalo to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to St. Louis

Sunday is one of the best days to book for cheap flights from Buffalo to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from $91 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to St. Louis Flights

*Flight schedules are subject to change.

Explore a world of travel with Expedia

*Available to One Key members.