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$124 Cheap Flights from Buffalo (BUF) to St. Louis (STL)

View $124 flight on Mon, Aug 31, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Buffalo to St. Louis (BUF-STL)

Prices were available within the past 7 days and start at $124 for one-way flights and $254 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Oct 22 - Mon, Oct 26
BUF
Buffalo
STL
St. Louis
$254 Roundtrip, found 1 day ago
$254
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Oct 22 from Buffalo to St. Louis, returning Mon, Oct 26, priced at $254 found 1 day ago
Frontier Airlines
Thu, Oct 15 - Sat, Oct 17
BUF
Buffalo
STL
St. Louis
$258 Roundtrip, found 6 days ago
$258
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Oct 15 from Buffalo to St. Louis, returning Sat, Oct 17, priced at $258 found 6 days ago
Frontier Airlines
Thu, Aug 20 - Tue, Aug 25
BUF
Buffalo
STL
St. Louis
$274 Roundtrip, found 3 days ago
$274
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Aug 20 from Buffalo to St. Louis, returning Tue, Aug 25, priced at $274 found 3 days ago
Frontier Airlines
Fri, Sep 4 - Mon, Sep 7
BUF
Buffalo
STL
St. Louis
$276 Roundtrip, found 2 days ago
$276
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Sep 4 from Buffalo to St. Louis, returning Mon, Sep 7, priced at $276 found 2 days ago
Frontier Airlines
Thu, Aug 20 - Tue, Aug 25
BUF
Buffalo
STL
St. Louis
$279 Roundtrip, found 3 days ago
$279
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Aug 20 from Buffalo to St. Louis, returning Tue, Aug 25, priced at $279 found 3 days ago
Frontier Airlines
Fri, Sep 4 - Mon, Sep 7
BUF
Buffalo
STL
St. Louis
$281 Roundtrip, found 2 days ago
$281
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Sep 4 from Buffalo to St. Louis, returning Mon, Sep 7, priced at $281 found 2 days ago
Southwest Airlines
Tue, Oct 6 - Thu, Oct 8
BUF
Buffalo
STL
St. Louis
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Tue, Oct 6 from Buffalo to St. Louis, returning Thu, Oct 8, priced at $290 found 6 days ago
American Airlines
Thu, Sep 10 - Thu, Sep 17
BUF
Buffalo
STL
St. Louis
$309 Roundtrip, found 1 hour ago
$309
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Sep 10 from Buffalo to St. Louis, returning Thu, Sep 17, priced at $309 found 1 hour ago
United
Thu, Aug 27 - Tue, Sep 1
BUF
Buffalo
STL
St. Louis
$309 Roundtrip, found 3 hours ago
$309
Roundtrip
found 3 hours ago
Select United flight, departing Thu, Aug 27 from Buffalo to St. Louis, returning Tue, Sep 1, priced at $309 found 3 hours ago
Delta
Thu, Aug 27 - Tue, Sep 1
BUF
Buffalo
STL
St. Louis
$314 Roundtrip, found 3 hours ago
$314
Roundtrip
found 3 hours ago
Select Delta flight, departing Thu, Aug 27 from Buffalo to St. Louis, returning Tue, Sep 1, priced at $314 found 3 hours ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $393
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $393

Find the cheapest month to fly from Buffalo (BUF) to St. Louis (STL)

January is typically the cheapest month to fly

From $166 - $511 per traveler.

What you need to know for your flight from Buffalo Niagara Intl. to Lambert-St. Louis Intl.

Buffalo (BUF) to St. Louis (STL) at a glance

Travel with a selection of airlines offering routes from Buffalo (BUF) to St. Louis (STL) on this domestic short-haul journey. Evaluate your choices between full-service and budget carriers to discover the itinerary that aligns with your budget, schedule, and travel plans as you delve into St. Louis's iconic attractions and neighborhoods. Find all the essential information for flights departing from Buffalo Niagara International Airport (BUF) to Lambert-St. Louis International Airport (STL).

  • Fastest flight duration: around 3h 45m non-stop
  • Route distance: roughly 700 miles (1,130 km)
  • Flights per week: around 11 departures on average
  • Typical fares (one-way): economy tickets often range from $110–$390, depending on seasonality and how far ahead you book

Flights from Buffalo Niagara International Airport (BUF) to Lambert-St. Louis International Airport (STL)

According to recent traveler bookings, here are the top airlines preferred for flights from Buffalo to St. Louis, featuring both non-stop and one-stop options. Many travelers opt for layovers at O'Hare International Airport (ORD) with an average layover of about 1 hour and 15 minutes, Detroit Metropolitan Wayne County Airport (DTW) at approximately 1 hour and 30 minutes, and Midway International Airport (MDW) also around 1 hour and 15 minutes. This variety allows you to balance price, total travel time, and cabin class for the best itinerary.

  • American Airlines: This major carrier provides full-service options with one-stop flights, featuring one-way fares that generally fall between $115 and $400. It represents about 33% of departures on this route, with an in-flight duration of 3 hours and 30 minutes, totaling approximately 4 hours and 45 minutes when including the layover.
  • Delta: Another full-service airline, Delta offers one-stop flights, with one-way ticket prices usually ranging from $120 to $410. It accounts for roughly 28% of departures on this route, maintaining a flight time of 3 hours and 30 minutes, with an overall journey time of about 4 hours and 45 minutes, including layover time.
  • Southwest Airlines: This budget airline provides both non-stop and one-stop services, with one-way fares typically between $120 and $390. Southwest accounts for approximately 26% of departures on this route, featuring a flight time of 3 hours and 30 minutes, leading to a total journey duration of around 4 hours and 45 minutes.
  • United: United Airlines is a full-service carrier offering one-stop options, with one-way fares generally priced from $110 to $430. It covers about 11% of departures on this route, with an in-flight time of 3 hours and 30 minutes, resulting in a total travel time of roughly 4 hours and 45 minutes, including layovers.
  • Frontier Airlines: This low-cost airline offers one-stop flights, with one-way fares typically ranging from $110 to $170. Frontier makes up about 2% of departures on this route, maintaining an in-flight duration of 3 hours and 30 minutes, and a total travel time of approximately 4 hours and 45 minutes, including layover periods.

Travelers flying from Buffalo to St. Louis have the option to enhance their experience with upgraded seating. Delta offers first class and premium economy class, while American Airlines provides first class service for a more comfortable journey.

Best time to fly from Buffalo (BUF) to St. Louis (STL)

The most popular months for travelers flying from Buffalo to St. Louis are March, April, and August, when peak temperatures in St. Louis reach up to 77°F in August. If you prefer quieter travel, consider June, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 76.1°F. For better deals, May usually offers the lowest average one-way fare around $175. Flight availability peaks in July, August, and November, with approximately 13 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: May usually offers good deals with average one-way fare around $175, roughly 23% cheaper than the yearly average.
  • More budget-friendly months to fly: September and August typically offer average one-way fares of around $186.
  • Most flight options: July, August, and November have the highest number of flights from Buffalo to St. Louis, with approximately 13 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January31.6°F (-0.2°C)Average8$291
February34.9°F (1.6°C)Slightly Low9$246
March46.4°F (8.0°C)Slightly High12$259
April56.1°F (13.4°C)Slightly High12$228
May66.6°F (19.2°C)Average11$175
June76.1°F (24.5°C)Slightly Low12$225
July78.6°F (25.9°C)Average13$207
August77.0°F (25.0°C)Slightly High13$189
September70.9°F (21.6°C)Average11$183
October58.6°F (14.8°C)Average12$226
November46.2°F (7.9°C)Average13$243
December37.8°F (3.2°C)Slightly Low12$267

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Buffalo (BUF) to St. Louis (STL)

  • Rochester to St. Louis (ROC-STL): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). The typical price range for one-way economy tickets on this route varies from $120 to $370, influenced by the season and how far in advance you book. This route generally features one-stop flights, with common layover spots at Detroit Metropolitan Wayne County Airport (DTW) and O'Hare International Airport (ORD). Major airlines servicing this route include American Airlines and Delta, with first class also offered.

How to find the best prices for flights from Buffalo (BUF) to St. Louis (STL)

Getting some of the best deals on flights from Buffalo to St. Louis is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking at least two months in advance, although most travelers reserve their flights two to eight weeks ahead. Afternoon departures from 12 PM to 6 PM often offer lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Tuesday typically yields cheaper rates, despite Thursday being the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Lambert-St. Louis International Airport from Buffalo Niagara International Airport

St. Louis welcomes travelers from Buffalo with a range of transport options based on price, convenience, and proximity. Here's how to reach St. Louis efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in St. Louis, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Lambert-St. Louis International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Lambert-St. Louis International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Lambert-St. Louis International Airport, Lambert Main Terminal Station, a metro station, is conveniently located just 0.1 miles away on foot, providing easy access to public transportation for travelers.

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find cheap one-way flights from $124 and cheap return flights from $254 Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) with Expedia. One-way flights generally range between $149 and $656, and roundtrip flights usually range from $280 to $1050. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
September is the cheapest month to fly from Buffalo (BUF) to St. Louis (STL), with average round-trip fares around $309. This is about 23% lower than the average price throughout the year, as September often has less travel activity after the summer. Other cheap months to consider are May and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter BUF to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Buffalo Niagara Intl. (BUF) to Lambert-St. Louis Intl. (STL), with round-trip tickets starting from around $168. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The best times to fly from Buffalo, NY (BUF) to St. Louis, MO (STL) are August and September. In September, you can find return flights for about $309, making it a cost-effective option. These months are popular for travel, providing a good mix of price and availability, according to booking data from the past year.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from BUF to STL. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from Buffalo Niagara International Airport (BUF) to Lambert-St. Louis International Airport (STL) are in the early morning, from 6am to 9am. About 32% of passengers prefer this time window. Many major carriers, including Southwest Airlines, American Airlines, and Delta, offer flights during this window. This timing works well because it allows you to start your day early and arrive in St. Louis with plenty of time to explore.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
A flight from BUF to STL with a layover takes around 6 hours 30 minutes, with the route covering approximately 673 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You can fly first class between BUF and STL. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis from Buffalo Niagara Intl. (BUF)?
From Buffalo Niagara Intl. (BUF), you can fly into Lambert-St. Louis Intl. (STL) to reach St. Louis. Some flights may connect through major hubs like Baltimore Washington Intl. Thurgood Marshall (BWI), Washington Dulles Intl. (IAD), Midway Intl. (MDW) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) St Louis Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$254
Distance
672 mi

Book with confidence

Buffalo to St. Louis Flights

The cheapest times to fly from Buffalo to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to St. Louis are during the month of October. You can find some of the cheapest flights from Buffalo to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to St. Louis

Sunday is one of the best days to book for cheap flights from Buffalo to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to St. Louis in 2026. You can also book with separate airlines for your outbound and return journeys, from $124 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to St. Louis Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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