$249 Cheap Flights from Mosinee (CWA) to Des Moines (DSM)

View $249 flight on Thu, Oct 30, 2025Opens in a new window

Popular airlines from Mosinee, WI (CWA-Central Wisconsin) to Des Moines International Airport (DSM)

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Cheap Flights from Mosinee to Des Moines (CWA-DSM)

Prices were available within the past 7 days and start at $249 for one-way flights and $317 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Oct 23 - Tue, Oct 28
CWA
Mosinee
DSM
Des Moines
$317 Roundtrip, found 6 days ago
$317
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Oct 23 from Mosinee to Des Moines, returning Tue, Oct 28, priced at $317 found 6 days ago
Delta
Thu, Oct 23 - Mon, Oct 27
CWA
Mosinee
DSM
Des Moines
$327 Roundtrip, found 6 days ago
$327
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Oct 23 from Mosinee to Des Moines, returning Mon, Oct 27, priced at $327 found 6 days ago
Delta
Mon, Oct 27 - Sat, Nov 1
CWA
Mosinee
DSM
Des Moines
$353 Roundtrip, found 6 days ago
$353
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Oct 27 from Mosinee to Des Moines, returning Sat, Nov 1, priced at $353 found 6 days ago
Delta
Thu, Oct 23 - Sun, Oct 26
CWA
Mosinee
DSM
Des Moines
$462 Roundtrip, found 6 days ago
$462
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Oct 23 from Mosinee to Des Moines, returning Sun, Oct 26, priced at $462 found 6 days ago
Delta
Tue, Oct 28 - Fri, Oct 31
CWA
Mosinee
DSM
Des Moines
$496 Roundtrip, found 6 days ago
$496
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 28 from Mosinee to Des Moines, returning Fri, Oct 31, priced at $496 found 6 days ago
American Airlines
Sun, Oct 26 - Wed, Oct 29
CWA
Mosinee
DSM
Des Moines
$500 Roundtrip, found 6 days ago
$500
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Oct 26 from Mosinee to Des Moines, returning Wed, Oct 29, priced at $500 found 6 days ago

Frequently asked questions

How much does a flight from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM) cost?
Grab a cheap one-way flight from $249 or cheap return flight from $317 from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM)?
The cheapest month to fly from CWA to DSM is October, when there's less demand. Off-peak months are typically when better flight deals are available between these airports.
What is the cheapest airline that flies from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from CWA to DSM. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM)?
You'll have to book a flight with a layover when traveling from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from CWA to DSM?
Typically you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM)?
To avoid possible delays on the Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM) route, aim to travel before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute bookings from CWA to DSM are generally more expensive. To secure the lowest rates, start searching for flights well in advance. That said, if your travel plans are flexible, you may score a cheap fare right before you leave.
Is it cheaper to book a CWA to DSM flight and hotel package?
Opting for a CWA to DSM flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our impressive range of stays and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Central Wisconsin Airport (CWA) to Des Moines Intl. Airport (DSM)?
It's usually possible to reschedule or cancel your CWA to DSM flight. However, for bookings made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Central Wisconsin
Destination airport
Des Moines Intl.
Roundtrip price
$316
Distance
300 mi

Book with confidence

Book with confidence

Mosinee to Des Moines Flights

The cheapest times to fly from Mosinee to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mosinee to Des Moines are during the month of October. You can find some of the cheapest flights from Mosinee to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mosinee to Des Moines

Sunday is one of the best days to book for cheap flights from Mosinee to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mosinee to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mosinee to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $249 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mosinee to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mosinee to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mosinee to Des Moines Flights

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*Available to One Key members.