$304 Cheap Flights from Cozumel (CZM) to Des Moines (DSM)

View $304 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Cozumel Intl. Airport (CZM) to Des Moines International Airport (DSM)

Cheap Flights from Cozumel to Des Moines (CZM-DSM)

Prices were available within the past 7 days and start at $304 for one-way flights and $443 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Dec 3 - Wed, Dec 10
CZM
Cozumel
DSM
Des Moines
$443 Roundtrip, found 4 days ago
$443
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 3 from Cozumel to Des Moines, returning Wed, Dec 10, priced at $443 found 4 days ago
American Airlines
Wed, Dec 3 - Wed, Dec 10
CZM
Cozumel
DSM
Des Moines
$451 Roundtrip, found 4 days ago
$451
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 3 from Cozumel to Des Moines, returning Wed, Dec 10, priced at $451 found 4 days ago
American Airlines
Wed, Dec 3 - Wed, Dec 10
CZM
Cozumel
DSM
Des Moines
$499 Roundtrip, found 4 days ago
$499
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 3 from Cozumel to Des Moines, returning Wed, Dec 10, priced at $499 found 4 days ago
American Airlines
Wed, Dec 3 - Wed, Dec 10
CZM
Cozumel
DSM
Des Moines
$507 Roundtrip, found 4 days ago
$507
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 3 from Cozumel to Des Moines, returning Wed, Dec 10, priced at $507 found 4 days ago
United
Wed, Jan 21 - Tue, Jan 27
CZM
Cozumel
DSM
Des Moines
$510 Roundtrip, found 6 hours ago
$510
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Jan 21 from Cozumel to Des Moines, returning Tue, Jan 27, priced at $510 found 6 hours ago
United
Wed, Jan 21 - Tue, Jan 27
CZM
Cozumel
DSM
Des Moines
$515 Roundtrip, found 6 hours ago
$515
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Jan 21 from Cozumel to Des Moines, returning Tue, Jan 27, priced at $515 found 6 hours ago
American Airlines
Wed, Jan 21 - Tue, Jan 27
CZM
Cozumel
DSM
Des Moines
$519 Roundtrip, found 6 hours ago
$519
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Jan 21 from Cozumel to Des Moines, returning Tue, Jan 27, priced at $519 found 6 hours ago
Aeromexico
Wed, Jan 21 - Tue, Jan 27
CZM
Cozumel
DSM
Des Moines
$765 Roundtrip, found 6 hours ago
$765
Roundtrip
found 6 hours ago
Select Aeromexico flight, departing Wed, Jan 21 from Cozumel to Des Moines, returning Tue, Jan 27, priced at $765 found 6 hours ago
Delta
Wed, Jan 21 - Tue, Jan 27
CZM
Cozumel
DSM
Des Moines
$866 Roundtrip, found 6 hours ago
$866
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Jan 21 from Cozumel to Des Moines, returning Tue, Jan 27, priced at $866 found 6 hours ago
Air Canada
Wed, Jan 21 - Tue, Jan 27
CZM
Cozumel
DSM
Des Moines
$1,535 Roundtrip, found 6 hours ago
$1,535
Roundtrip
found 6 hours ago
Select Air Canada flight, departing Wed, Jan 21 from Cozumel to Des Moines, returning Tue, Jan 27, priced at $1,535 found 6 hours ago
Flights from Cozumel (CZM) to Des Moines (DSM)
Origin airport
Cozumel Intl.
Destination airport
Des Moines Intl.
Roundtrip price
$442
Distance
1504 mi

Cozumel to Des Moines Flights

The cheapest times to fly from Cozumel to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cozumel to Des Moines are during the month of December. You can find some of the cheapest flights from Cozumel to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cozumel to Des Moines

Sunday is one of the best days to book for cheap flights from Cozumel to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cozumel to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cozumel to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $304 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cozumel to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cozumel to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM) cost?
Secure a cheap one-way flight from $304 or cheap return flight from $443 from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM)?
December is the most affordable month to fly from CZM to DSM. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM)?
To find the cheapest airline flying from CZM to DSM, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM)?
You'll need to take a flight with a layover when traveling from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from CZM to DSM?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on a number of factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM)?
To avoid possible delays on the Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM) route, aim to travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from CZM to DSM are typically more expensive. To secure the lowest rates, start searching for flights well in advance. That said, if you're flexible with your travel dates, you may land a cheap fare right before your journey.
Is it cheaper to book a CZM to DSM flight and hotel package?
Compared with arranging hotels and flights separately, booking a CZM to DSM flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one convenient place will take the hassle out of planning your trip. Just secure your flights and select from our wide range of stays, then tailor your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Cozumel Intl. Airport (CZM) to Des Moines Intl. Airport (DSM)?
It's generally possible to cancel or reschedule your CZM to DSM flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.