$329 Cheap Flights from Dothan (DHN) to Des Moines (DSM)

View $329 flight on Thu, Feb 26, 2026Opens in a new window

Popular airlines from Dothan, AL (DHN-Dothan Regional) to Des Moines International Airport (DSM)

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Cheap Flights from Dothan to Des Moines (DHN-DSM)

Prices were available within the past 7 days and start at $329 for one-way flights and $367 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Jan 27 - Tue, Feb 10
DHN
Dothan
DSM
Des Moines
$367 Roundtrip, found 2 days ago
$367
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jan 27 from Dothan to Des Moines, returning Tue, Feb 10, priced at $367 found 2 days ago
Delta
Tue, Feb 3 - Wed, Feb 18
DHN
Dothan
DSM
Des Moines
$372 Roundtrip, found 2 days ago
$372
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Feb 3 from Dothan to Des Moines, returning Wed, Feb 18, priced at $372 found 2 days ago
Delta
Thu, Jan 22 - Tue, Feb 10
DHN
Dothan
DSM
Des Moines
$377 Roundtrip, found 2 days ago
$377
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Jan 22 from Dothan to Des Moines, returning Tue, Feb 10, priced at $377 found 2 days ago
Delta
Thu, Jan 29 - Wed, Feb 18
DHN
Dothan
DSM
Des Moines
$382 Roundtrip, found 2 days ago
$382
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Jan 29 from Dothan to Des Moines, returning Wed, Feb 18, priced at $382 found 2 days ago
Delta
Sun, Jan 11 - Wed, Jan 28
DHN
Dothan
DSM
Des Moines
$387 Roundtrip, found 2 days ago
$387
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Jan 11 from Dothan to Des Moines, returning Wed, Jan 28, priced at $387 found 2 days ago
Delta
Sun, Jan 11 - Tue, Jan 27
DHN
Dothan
DSM
Des Moines
$392 Roundtrip, found 2 days ago
$392
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Jan 11 from Dothan to Des Moines, returning Tue, Jan 27, priced at $392 found 2 days ago
Delta
Sun, Jan 11 - Sun, Jan 25
DHN
Dothan
DSM
Des Moines
$397 Roundtrip, found 2 days ago
$397
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Jan 11 from Dothan to Des Moines, returning Sun, Jan 25, priced at $397 found 2 days ago
Delta
Sun, Jan 11 - Sat, Jan 24
DHN
Dothan
DSM
Des Moines
$402 Roundtrip, found 2 days ago
$402
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Jan 11 from Dothan to Des Moines, returning Sat, Jan 24, priced at $402 found 2 days ago
Delta
Thu, Jan 29 - Sun, Feb 1
DHN
Dothan
DSM
Des Moines
$457 Roundtrip, found 2 days ago
$457
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Jan 29 from Dothan to Des Moines, returning Sun, Feb 1, priced at $457 found 2 days ago
Delta
Fri, Jan 23 - Tue, Feb 10
DHN
Dothan
DSM
Des Moines
$463 Roundtrip, found 2 days ago
$463
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Jan 23 from Dothan to Des Moines, returning Tue, Feb 10, priced at $463 found 2 days ago

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $463
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $463

Frequently asked questions

How much does a flight from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM) cost?
Secure a cheap one-way flight from $329 or cheap return flight from $367 from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM)?
Flying in January is a great way to save, as it's the cheapest month for flights between DHN and DSM. You'll often find the lowest fares during off-peak months.
What is the cheapest airline that flies from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll take you from DHN to DSM. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM)?
Nonstop flights from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DHN to DSM?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on a range of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM)?
To land at Des Moines Intl. Airport (DSM) without delays, select a flight that takes off from Dothan Regional Airport (DHN) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM) last-minute?
Holding off until right before your break to book your flight from DHN to DSM often results in higher prices. While you may find some last-minute deals, there's no guarantee. Keep your travel schedule open for the best chance of landing a bargain.
Is it cheaper to book a DHN to DSM flight and hotel package?
Compared with arranging hotels and flights separately, booking a DHN to DSM flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place will take the hassle out of travel planning. Simply pick your flights and choose from our extensive range of stays, then tailor your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Dothan Regional Airport (DHN) to Des Moines Intl. Airport (DSM)?
If you reserved your DHN to DSM flight in the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Dothan Regional
Destination airport
Des Moines Intl.
Roundtrip price
$366
Distance
839 mi

Book with confidence

Dothan to Des Moines Flights

The cheapest times to fly from Dothan to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Dothan to Des Moines are during the month of January. You can find some of the cheapest flights from Dothan to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Dothan to Des Moines

Sunday is one of the best days to book for cheap flights from Dothan to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Dothan to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Dothan to Des Moines in 2026. You can also book with separate airlines for your outbound and return journeys, from $329 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Dothan to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Dothan to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Dothan to Des Moines Flights

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*Available to One Key members.