$752 Cheap Flights from Rome (FCO) to Des Moines (DSM)

View $752 flight on Wed, Apr 8, 2026Opens in a new window

Popular airlines from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines International Airport (DSM)

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Cheap Flights from Rome to Des Moines (FCO-DSM)

Prices were available within the past 7 days and start at $752 for one-way flights and $752 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Tue, Oct 14 - Sun, Oct 19
FCO
Rome
DSM
Des Moines
$752 Roundtrip, found 19 hours ago
$752
Roundtrip
found 19 hours ago
Select British Airways flight, departing Tue, Oct 14 from Rome to Des Moines, returning Sun, Oct 19, priced at $752 found 19 hours ago
American Airlines
Wed, Oct 8 - Sun, Oct 12
FCO
Rome
DSM
Des Moines
$758 Roundtrip, found 4 days ago
$758
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Oct 8 from Rome to Des Moines, returning Sun, Oct 12, priced at $758 found 4 days ago
British Airways
Tue, Oct 14 - Sun, Oct 19
FCO
Rome
DSM
Des Moines
$764 Roundtrip, found 19 hours ago
$764
Roundtrip
found 19 hours ago
Select British Airways flight, departing Tue, Oct 14 from Rome to Des Moines, returning Sun, Oct 19, priced at $764 found 19 hours ago
Delta
Thu, Jan 8 - Mon, Jan 12
FCO
Rome
DSM
Des Moines
$767 Roundtrip, found 3 days ago
$767
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jan 8 from Rome to Des Moines, returning Mon, Jan 12, priced at $767 found 3 days ago
American Airlines
Tue, Oct 7 - Sun, Oct 12
FCO
Rome
DSM
Des Moines
$769 Roundtrip, found 1 day ago
$769
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Oct 7 from Rome to Des Moines, returning Sun, Oct 12, priced at $769 found 1 day ago
American Airlines
Wed, Oct 8 - Wed, Oct 15
FCO
Rome
DSM
Des Moines
$771 Roundtrip, found 4 days ago
$771
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Oct 8 from Rome to Des Moines, returning Wed, Oct 15, priced at $771 found 4 days ago
Iberia
Tue, Oct 14 - Sun, Oct 19
FCO
Rome
DSM
Des Moines
$772 Roundtrip, found 19 hours ago
$772
Roundtrip
found 19 hours ago
Select Iberia flight, departing Tue, Oct 14 from Rome to Des Moines, returning Sun, Oct 19, priced at $772 found 19 hours ago
American Airlines
Tue, Oct 14 - Sun, Oct 19
FCO
Rome
DSM
Des Moines
$774 Roundtrip, found 19 hours ago
$774
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Oct 14 from Rome to Des Moines, returning Sun, Oct 19, priced at $774 found 19 hours ago
British Airways
Tue, Oct 14 - Sun, Oct 19
FCO
Rome
DSM
Des Moines
$775 Roundtrip, found 19 hours ago
$775
Roundtrip
found 19 hours ago
Select British Airways flight, departing Tue, Oct 14 from Rome to Des Moines, returning Sun, Oct 19, priced at $775 found 19 hours ago
Air France
Wed, Oct 8 - Tue, Oct 14
FCO
Rome
DSM
Des Moines
$840 Roundtrip, found 4 days ago
$840
Roundtrip
found 4 days ago
Select Air France flight, departing Wed, Oct 8 from Rome to Des Moines, returning Tue, Oct 14, priced at $840 found 4 days ago
Flights from Rome (FCO) to Des Moines (DSM)
Origin airport
Fiumicino - Leonardo da Vinci Intl.
Destination airport
Des Moines Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, British Airways, Delta, Iberia, KLM, Lufthansa, United
Roundtrip price
$752
Distance
5057 mi

Rome to Des Moines Flights

The cheapest times to fly from Rome to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rome to Des Moines are during the month of October. You can find some of the cheapest flights from Rome to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Rome to Des Moines

Sunday is one of the best days to book for cheap flights from Rome to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Rome to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rome to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $752 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rome to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Rome to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM) cost?
Snag a cheap one-way flight from $752 or cheap return flight from $752 from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM)?
October is the most affordable month to fly from FCO to DSM. Timing your trip outside of the busy season is often the key to finding a great deal.
What is the cheapest airline that flies from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM)?
To find the cheapest airline flying from FCO to DSM, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM)?
You'll have to hop on a flight with a layover if you're traveling from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from FCO to DSM?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM)?
To avoid possible delays on the Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM) route, fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute bookings from FCO to DSM are typically more expensive. To secure the best prices, start searching for flights well in advance. That being said, if you're flexible with your travel dates, you may find a cheap ticket right before your trip.
Is it cheaper to book a FCO to DSM flight and hotel package?
Booking a FCO to DSM flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Pick from our wide range of hotels and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Des Moines Intl. Airport (DSM)?
You can usually cancel or reschedule your FCO to DSM flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.