$332 Cheap Flights from Guadalajara (GDL) to Des Moines (DSM)

View $332 flight on Fri, Jan 23, 2026Opens in a new window

Popular airlines from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines International Airport (DSM)

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Cheap Flights from Guadalajara to Des Moines (GDL-DSM)

Prices were available within the past 7 days and start at $332 for one-way flights and $445 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Fri, Dec 12 - Mon, Dec 15
GDL
Guadalajara
DSM
Des Moines
$445 Roundtrip, found 5 days ago
$445
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Dec 12 from Guadalajara to Des Moines, returning Mon, Dec 15, priced at $445 found 5 days ago
Frontier Airlines
Fri, Dec 12 - Wed, Mar 11
GDL
Guadalajara
DSM
Des Moines
$521 Roundtrip, found 6 days ago
$521
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Dec 12 from Guadalajara to Des Moines, returning Wed, Mar 11, priced at $521 found 6 days ago
Frontier Airlines
Fri, Dec 12 - Tue, Dec 23
GDL
Guadalajara
DSM
Des Moines
$536 Roundtrip, found 5 days ago
$536
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Dec 12 from Guadalajara to Des Moines, returning Tue, Dec 23, priced at $536 found 5 days ago
Frontier Airlines
Fri, Dec 12 - Mon, Mar 9
GDL
Guadalajara
DSM
Des Moines
$550 Roundtrip, found 6 days ago
$550
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Dec 12 from Guadalajara to Des Moines, returning Mon, Mar 9, priced at $550 found 6 days ago
Delta
Wed, Dec 17 - Tue, Mar 10
GDL
Guadalajara
DSM
Des Moines
$551 Roundtrip, found 6 days ago
$551
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Dec 17 from Guadalajara to Des Moines, returning Tue, Mar 10, priced at $551 found 6 days ago
United
Mon, Dec 15 - Wed, Mar 11
GDL
Guadalajara
DSM
Des Moines
$551 Roundtrip, found 6 days ago
$551
Roundtrip
found 6 days ago
Select United flight, departing Mon, Dec 15 from Guadalajara to Des Moines, returning Wed, Mar 11, priced at $551 found 6 days ago
Aeromexico
Wed, Nov 26 - Wed, Feb 18
GDL
Guadalajara
DSM
Des Moines
$551 Roundtrip, found 6 days ago
$551
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Wed, Nov 26 from Guadalajara to Des Moines, returning Wed, Feb 18, priced at $551 found 6 days ago
American Airlines
Wed, Dec 10 - Wed, Mar 4
GDL
Guadalajara
DSM
Des Moines
$551 Roundtrip, found 6 days ago
$551
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Dec 10 from Guadalajara to Des Moines, returning Wed, Mar 4, priced at $551 found 6 days ago
American Airlines
Wed, Dec 3 - Wed, Jan 7
GDL
Guadalajara
DSM
Des Moines
$551 Roundtrip, found 2 days ago
$551
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Dec 3 from Guadalajara to Des Moines, returning Wed, Jan 7, priced at $551 found 2 days ago
United
Mon, Dec 15 - Wed, Mar 11
GDL
Guadalajara
DSM
Des Moines
$555 Roundtrip, found 6 days ago
$555
Roundtrip
found 6 days ago
Select United flight, departing Mon, Dec 15 from Guadalajara to Des Moines, returning Wed, Mar 11, priced at $555 found 6 days ago

Find the cheapest month to fly from Guadalajara (GDL) to Des Moines (DSM)

May is typically the cheapest month to fly

From $421 - $867 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $649
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $649

Frequently asked questions

How much does a flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight from $332 or cheap return flight from $445 from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM)?
The cheapest month to fly from GDL to DSM is December, when demand is low. Off-peak season is typically when airlines offer better prices between these airports.
What is the cheapest airline that flies from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM)?
To find the cheapest airline flying from GDL to DSM, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM)?
There are no daily nonstop flights from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from GDL to DSM?
Usually you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* But this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM)?
Select a flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM) last-minute?
Booking your ticket from GDL to DSM just before your trip is typically more expensive. But if there's some wiggle room with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a GDL to DSM flight and hotel package?
Opting for a GDL to DSM flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Des Moines Intl. Airport (DSM)?
If you reserved your GDL to DSM flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Travel information

Origin airport
Don Miguel Hidalgo y Costilla Intl.
Destination airport
Des Moines Intl.
Airlines serving
Aeromexico, Air Canada, American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$445
Distance
1557 mi

Book with confidence

Guadalajara to Des Moines Flights

The cheapest times to fly from Guadalajara to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guadalajara to Des Moines are during the month of December. You can find some of the cheapest flights from Guadalajara to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guadalajara to Des Moines

Sunday is one of the best days to book for cheap flights from Guadalajara to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guadalajara to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guadalajara to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $332 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guadalajara to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guadalajara to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Guadalajara to Des Moines Flights

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