$116 Cheap Flights from Harlingen (HRL) to Des Moines (DSM)

View $116 flight on Tue, Jan 20, 2026Opens in a new window

Popular airlines from Valley Intl. Airport (HRL) to Des Moines International Airport (DSM)

Cheap Flights from Harlingen to Des Moines (HRL-DSM)

Prices were available within the past 7 days and start at $116 for one-way flights and $241 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, Oct 31 - Tue, Nov 4
HRL
Harlingen
DSM
Des Moines
$241 Roundtrip, found 2 days ago
$241
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 31 from Harlingen to Des Moines, returning Tue, Nov 4, priced at $241 found 2 days ago
Delta
Fri, Oct 31 - Wed, Nov 5
HRL
Harlingen
DSM
Des Moines
$244 Roundtrip, found 2 days ago
$244
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Oct 31 from Harlingen to Des Moines, returning Wed, Nov 5, priced at $244 found 2 days ago
United
Fri, Oct 31 - Tue, Nov 4
HRL
Harlingen
DSM
Des Moines
$244 Roundtrip, found 2 days ago
$244
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 31 from Harlingen to Des Moines, returning Tue, Nov 4, priced at $244 found 2 days ago
United
Fri, Oct 31 - Tue, Nov 4
HRL
Harlingen
DSM
Des Moines
$246 Roundtrip, found 2 days ago
$246
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 31 from Harlingen to Des Moines, returning Tue, Nov 4, priced at $246 found 2 days ago
Delta
Fri, Oct 31 - Tue, Nov 4
HRL
Harlingen
DSM
Des Moines
$247 Roundtrip, found 2 days ago
$247
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Oct 31 from Harlingen to Des Moines, returning Tue, Nov 4, priced at $247 found 2 days ago
United
Fri, Oct 31 - Tue, Nov 4
HRL
Harlingen
DSM
Des Moines
$250 Roundtrip, found 2 days ago
$250
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 31 from Harlingen to Des Moines, returning Tue, Nov 4, priced at $250 found 2 days ago
United
Sat, Feb 7 - Tue, Feb 10
HRL
Harlingen
DSM
Des Moines
$253 Roundtrip, found 6 hours ago
$253
Roundtrip
found 6 hours ago
Select United flight, departing Sat, Feb 7 from Harlingen to Des Moines, returning Tue, Feb 10, priced at $253 found 6 hours ago
Delta
Tue, Nov 4 - Fri, Nov 14
HRL
Harlingen
DSM
Des Moines
$255 Roundtrip, found 10 hours ago
$255
Roundtrip
found 10 hours ago
Select Delta flight, departing Tue, Nov 4 from Harlingen to Des Moines, returning Fri, Nov 14, priced at $255 found 10 hours ago
Southwest Airlines
Wed, Oct 29 - Mon, Nov 10
HRL
Harlingen
DSM
Des Moines
$266 Roundtrip, found 6 days ago
$266
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Oct 29 from Harlingen to Des Moines, returning Mon, Nov 10, priced at $266 found 6 days ago
American Airlines
Sat, Feb 7 - Tue, Feb 10
HRL
Harlingen
DSM
Des Moines
$270 Roundtrip, found 6 hours ago
$270
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Feb 7 from Harlingen to Des Moines, returning Tue, Feb 10, priced at $270 found 6 hours ago

Find the cheapest month to fly from Harlingen (HRL) to Des Moines (DSM)

April is typically the cheapest month to fly

From $198 - $434 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $270
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $270

Frequently asked questions

How much does a flight from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM) cost?
Get a cheap one-way flight from $116 or cheap return flight from $241 from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM)?
October is the cheapest month to fly from HRL to DSM. Timing your trip outside of the busy season is often the key to better flight prices.
What is the cheapest airline that flies from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest HRL to DSM flight.
How many flights per day from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM)?
There aren't any daily direct flights departing from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from HRL to DSM?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change based on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM)?
To land at Des Moines Intl. Airport (DSM) without delays, choose a flight that leaves Valley Intl. Airport (HRL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from HRL to DSM are generally more expensive. To lock in the best prices, start looking for flights well in advance. That being said, if you're flexible with your travel plans, it's possible to land a cheap ticket right before you leave.
Is it cheaper to book a HRL to DSM flight and hotel package?
Securing a HRL to DSM flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Select from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Valley Intl. Airport (HRL) to Des Moines Intl. Airport (DSM)?
In most instances, you can cancel or reschedule your HRL to DSM flight. However, there may be additional fees, especially if you booked more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more information, head to our Customer Service portal.

Travel information

Origin airport
Valley Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$240
Distance
1082 mi

Book with confidence

Harlingen to Des Moines Flights

The cheapest times to fly from Harlingen to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Harlingen to Des Moines are during the month of October. You can find some of the cheapest flights from Harlingen to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Harlingen to Des Moines

Sunday is one of the best days to book for cheap flights from Harlingen to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Harlingen to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Harlingen to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $116 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Harlingen to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Harlingen to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Harlingen to Des Moines Flights

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*Available to One Key members.