$245 Cheap Flights from St. Thomas (STT) to Des Moines (DSM)

View $245 flight on Thu, Mar 12, 2026Opens in a new window

Popular airlines from Cyril E. King Airport (STT) to Des Moines International Airport (DSM)

Cheap Flights from St. Thomas to Des Moines (STT-DSM)

Prices were available within the past 7 days and start at $245 for one-way flights and $485 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$485 Roundtrip, found 3 days ago
$485
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $485 found 3 days ago
Delta
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$489 Roundtrip, found 3 days ago
$489
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $489 found 3 days ago
American Airlines
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$497 Roundtrip, found 3 days ago
$497
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $497 found 3 days ago
American Airlines
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$532 Roundtrip, found 3 days ago
$532
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $532 found 3 days ago
Delta
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$550 Roundtrip, found 3 days ago
$550
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $550 found 3 days ago
American Airlines
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$572 Roundtrip, found 3 days ago
$572
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $572 found 3 days ago
American Airlines
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$584 Roundtrip, found 3 days ago
$584
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $584 found 3 days ago
American Airlines
Wed, Jan 21 - Sun, Jan 25
STT
St. Thomas
DSM
Des Moines
$595 Roundtrip, found 3 days ago
$595
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Jan 21 from St. Thomas to Des Moines, returning Sun, Jan 25, priced at $595 found 3 days ago
United
Sat, Oct 4 - Sat, Oct 11
STT
St. Thomas
DSM
Des Moines
$688 Roundtrip, found 4 days ago
$688
Roundtrip
found 4 days ago
Select United flight, departing Sat, Oct 4 from St. Thomas to Des Moines, returning Sat, Oct 11, priced at $688 found 4 days ago
Southwest Airlines
Sat, Mar 14 - Sat, Mar 21
STT
St. Thomas
DSM
Des Moines
$1,244 Roundtrip, found 4 days ago
$1,244
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Sat, Mar 14 from St. Thomas to Des Moines, returning Sat, Mar 21, priced at $1,244 found 4 days ago
Flights from St. Thomas (STT) to Des Moines (DSM)
Origin airport
Cyril E. King
Destination airport
Des Moines Intl.
Roundtrip price
$485
Distance
2328 mi

St. Thomas to Des Moines Flights

The cheapest times to fly from St. Thomas to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Thomas to Des Moines are during the month of January. You can find some of the cheapest flights from St. Thomas to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Thomas to Des Moines

Sunday is one of the best days to book for cheap flights from St. Thomas to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Thomas to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Thomas to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $245 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Thomas to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Thomas to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight from $245 or cheap return flight from $485 from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM)?
Traveling in January can help you save, as it's the cheapest month for flights between STT and DSM. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from STT to DSM. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM)?
You'll have to catch a flight with a layover when traveling from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from STT to DSM?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM)?
To avoid possible delays on the Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM) route, fly before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM) last-minute?
Last-minute fares from STT to DSM are typically more expensive. For the lowest rates, start searching for flights as early as possible. That being said, if you can play around with your travel dates, you may land a cheap fare right before your trip.
Is it cheaper to book a STT to DSM flight and hotel package?
Opting for a STT to DSM flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our extensive range of stays and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cyril E. King Airport (STT) to Des Moines Intl. Airport (DSM)?
If you reserved your STT to DSM flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

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*Available to One Key members.