This is the skyline at sunrise. It is situated along the Mississippi River. There are riverboats on the water with the St. Louis Arch in clear view.

Find 4 Star Hotels in Affton, MO from $111

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check availability on Affton 4 Star Hotels

Our top choices for Affton 4-star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,120 reviews)
"Clean room, helpful & friendly staff, well located."
United States
MICHELLE
$134 nightly
The price is $158
Jun 19 - Jun 20
Total with taxes and fees
Hyatt Regency St. Louis at The Arch

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very Good, (1,109 reviews)
"Great location to the airport and staff was very welcoming!"
United States
James
$135 nightly
The price is $158
Jul 9 - Jul 10
Total with taxes and fees
Renaissance St. Louis Airport Hotel

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (725 reviews)
"Dinning and pool areas were enjoyable."
United States
Robert
$152 nightly
The price is $179
Jul 5 - Jul 6
Total with taxes and fees
Le Méridien St. Louis Clayton

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1,021 reviews)
"Great hotel!"
United States
Terence Peter
$198 nightly
The price is $234
Jun 28 - Jun 29
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,908 reviews)
"Great stay!"
United States
Quentin
$156 nightly
The price is $183
Jun 21 - Jun 22
Total with taxes and fees
21C Museum Hotel St Louis

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very Good, (1,025 reviews)
"The room was nice and the staff was friendly. Perfect spot to stay if you’re going out on the town for the night."
United States
Jenna
$152 nightly
The price is $181
Jun 26 - Jun 27
Total with taxes and fees
Marriott St. Louis Grand

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,225 reviews)
"Hotel was stunning, breakfast was amazing and the location was perfect!"
United States
Julie
$159 nightly
The price is $189
Jun 21 - Jun 22
Total with taxes and fees
Live by Loews - St.Louis

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,623 reviews)
"Would stay again in a heartbeat!"
United States
Austin
$95 nightly
The price is $111
Jun 29 - Jun 30
Total with taxes and fees
River City Casino & Hotel

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,166 reviews)
"Staff was excellent and accommodating. Bistro food outstanding. Ideal location."
United States
Daniel
$171 nightly
The price is $204
Jun 28 - Jun 29
Total with taxes and fees
Hilton St. Louis at the Ballpark

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,023 reviews)
"Good unique stay."
United States
Caleb
$161 nightly
The price is $191
Jun 21 - Jun 22
Total with taxes and fees
The Cheshire

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,978 reviews)
"Fantastic place, great theme, friendly and fun staff, they seem to enjoy their job"
United States
Amy
$175 nightly
The price is $208
Jun 28 - Jun 29
Total with taxes and fees
Moonrise Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,304 reviews)
"The staff could not have been nicer even holding our luggage before and after checkout. The beds were super comfy and the rooms extra spacious with a living room area separate from the sleeping space. And just a short walk to Busch Stadium and the arch!!"
United States
Cherie
$108 nightly
The price is $128
Jun 28 - Jun 29
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,014 reviews)
"Great stay!"
United States
Matiah
$193 nightly
The price is $226
Jul 1 - Jul 2
Total with taxes and fees
Ameristar Casino Resort and Spa

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,015 reviews)
"The staff was pleasant and the property was clean."
United States
Bayyan
$140 nightly
The price is $164
Jun 21 - Jun 22
Total with taxes and fees
The Westin St. Louis

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,021 reviews)
"Great staff clean property nice location"
United States
Karen
$136 nightly
The price is $161
Jun 21 - Jun 22
Total with taxes and fees
Drury Plaza Hotel St. Louis Brentwood

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very Good, (1,002 reviews)
"Beautiful hotel in a convenient locations. Walking distance to great restaurants and coffee shops."
United States
Gary
$122 nightly
The price is $144
Jul 2 - Jul 3
Total with taxes and fees
DoubleTree by Hilton St. Louis Forest Park

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,018 reviews)
"Great stay and so much to do close by!"
United States
Rachel
$158 nightly
The price is $188
Jun 20 - Jun 21
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,084 reviews)
"Great location and staff."
United States
Colette
$130 nightly
The price is $154
Jun 21 - Jun 22
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch

Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very Good, (1,004 reviews)
"Lovely"
United States
Yvonne
$152 nightly
The price is $181
Jul 4 - Jul 5
Total with taxes and fees
Marriott St. Louis Airport

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,342 reviews)
"Definitely would stay again."
United States
Travis
$130 nightly
The price is $155
Jun 28 - Jun 29
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Affton.
Still don't see what you're looking for?
See all properties in Affton.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Affton

This small St. Louis suburb offers family fun at Affton Plaza Bowl and Grant's Farm with its Budweiser Clydesdales. Grab a slice at local favorite Pirrone's Pizzeria, then catch a Cardinals game or visit the Gateway Arch in nearby St. Louis.

This is the skyline at sunrise. It is situated along the Mississippi River. There are riverboats on the water with the St. Louis Arch in clear view.

Top Affton Hotel Reviews

Find out more about Affton

Affton Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Affton, St. Louis are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Affton 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Affton. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Affton, St. Louis, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Affton hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Affton?
River City Casino & Hotel is a 4-star hotel in Affton that rates highly among Expedia travelers. A pillowtop mattress and a rainfall shower-head are a couple of its amenities. Travelers also love The Cheshire. From a swimming pool to a pillowtop mattress, it comes with conveniences that cater to every aspect of your enjoyment and relaxation.
How much does it cost to stay in a 4-star hotel in Affton?
With Expedia's sort and search filters, scoring a terrific deal on a 4-star hotel in Affton just got simpler. Start by keying in your chosen arrival date and length of your trip. Then list the results by price and pick a property that best fits your style and budget.

  • Search for the lowest price from $415

What's the difference between 5-star and 4-star hotels in Affton?
If you choose to stay at a 4-star hotel in Affton, you'll usually find loads of conveniences to make sure you're comfortable, such as a gym, restaurant and pool. You can look forward to high-quality service and upmarket surroundings. Go for a 5-star hotel and you'll have access to a few extra bells and whistles — think concierge assistance, on-site spas and indulgent turndown services. You're likely to get additional amenities and premium services at a 5-star stay, but both are awesome options for luxury travelers.

Explore a world of travel with Expedia