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Find 4 Star Hotels in Otay Mesa West, CA from $275
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Compare Otay Mesa West 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
9.0 out of 10, Wonderful, (3110)
The price is $197
$270 total
includes taxes & fees
Jul 1 - Jul 2
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
8.8 out of 10, Excellent, (1775)
The price is $212
$274 total
includes taxes & fees
Jul 2 - Jul 3
Sheraton San Diego Hotel and Marina
Sheraton San Diego Hotel and Marina
7.8 out of 10, Good, (2229)
The price is $194
$248 total
includes taxes & fees
Jul 21 - Jul 22
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Wyndham San Diego Bayside
Wyndham San Diego Bayside
8.2 out of 10, Very Good, (5815)
The price is $169
$191 total
includes taxes & fees
Jul 2 - Jul 3
Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
8.8 out of 10, Excellent, (2179)
The price is $209
$278 total
includes taxes & fees
Jul 2 - Jul 3
Hilton San Diego Bayfront
Hilton San Diego Bayfront
8.4 out of 10, Very Good, (1498)
The price is $155
$222 total
includes taxes & fees
Jul 2 - Jul 3
Paradise Point Resort & Spa
Paradise Point Resort & Spa
8.4 out of 10, Very Good, (1818)
The price is $299
$382 total
includes taxes & fees
Jun 23 - Jun 24
San Diego Marriott Gaslamp Quarter
San Diego Marriott Gaslamp Quarter
8.6 out of 10, Excellent, (1088)
The price is $203
$229 total
includes taxes & fees
Jun 23 - Jun 24
San Diego Mission Bay Resort
San Diego Mission Bay Resort
8.2 out of 10, Very Good, (1036)
The price is $303
$385 total
includes taxes & fees
Jun 27 - Jun 28
The Westin San Diego Bayview
The Westin San Diego Bayview
8.4 out of 10, Very Good, (1005)
The price is $170
$217 total
includes taxes & fees
Jul 1 - Jul 2
Hilton San Diego Mission Valley
Hilton San Diego Mission Valley
7.6 out of 10, Good, (1067)
The price is $146
$164 total
includes taxes & fees
Jun 23 - Jun 24
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and Marina
8.4 out of 10, Very Good, (1418)
The price is $269
$347 total
includes taxes & fees
Jun 27 - Jun 28
InterContinental San Diego, an IHG Hotel
InterContinental San Diego, an IHG Hotel
9.0 out of 10, Wonderful, (1004)
The price is $217
$292 total
includes taxes & fees
Jul 1 - Jul 2
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
9.0 out of 10, Wonderful, (2863)
The price is $229
$258 total
includes taxes & fees
Jun 23 - Jun 24
Coronado Island Marriott Resort & Spa
Coronado Island Marriott Resort & Spa
8.4 out of 10, Very Good, (1003)
The price is $280
$355 total
includes taxes & fees
Jun 30 - Jul 1
Palihotel San Diego
Palihotel San Diego
8.8 out of 10, Excellent, (571)
The price is $110
$152 total
includes taxes & fees
Jun 23 - Jun 24
Town and Country San Diego
Town and Country San Diego
7.8 out of 10, Good, (1170)
The price is $209
$258 total
includes taxes & fees
Jun 21 - Jun 22
Margaritaville Hotel San Diego Gaslamp Quarter
Margaritaville Hotel San Diego Gaslamp Quarter
9.0 out of 10, Wonderful, (412)
The price is $215
$276 total
includes taxes & fees
Jul 2 - Jul 3
Loews Coronado Bay Resort
Loews Coronado Bay Resort
8.6 out of 10, Excellent, (1028)
The price is $249
$323 total
includes taxes & fees
Jun 23 - Jun 24
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
8.8 out of 10, Excellent, (472)
The price is $149
$203 total
includes taxes & fees
Jun 23 - Jun 24
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Otay Mesa West.
![Pendry San Diego](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05e1c8e8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)
Pendry San Diego
550 J Street, San Diego, CA
The price is $293 per night from Jul 21 to Jul 22
$293
$380 total
includes taxes & fees
Jul 21 - Jul 22
9.2/10 Wonderful! (1,006 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent reviews of Otay Mesa West hotelsExpedia verified reviews
![Manchester Grand Hyatt San Diego](http://images.trvl-media.com/lodging/1000000/20000/12100/12073/216656e5_y.jpg)
Manchester Grand Hyatt San Diego
5/5 Excellent
"The Grand Hyatt is an excellent choice for a brief vacation. The hotel is clean, and it's conveniently located near numerous restaurants and the beach."
A verified traveler stayed at Manchester Grand Hyatt San Diego
Posted 13 hours ago
Otay Mesa West Hotels by Star Rating
Hotels in Otay Mesa West Neighborhoods
Stay near popular Otay Mesa West attractions
- San Diego Zoo
- Mission Bay
- San Diego Convention Center
- Petco Park
- Mission Beach
- San Ysidro Border Crossing
- Balboa Park
- Hotel Circle
- Naval Base San Diego
- San Diego State University
- USS Midway Museum
- Marine Corps Recruit Depot
- Mission Beach Boardwalk
- University of San Diego
- Coronado Beach
- Hotel del Coronado
- Seaport Village
- Naval Base Coronado
- Las Americas Premium Outlets
- Port of San Diego
More Hotel Options in Otay Mesa West
Explore more hotels
- Sheraton San Diego Hotel and Marina
- Bahia Resort Hotel
- Marriott Marquis San Diego Marina
- Best Western Plus Marina Gateway Hotel
- Legacy Resort Hotel & Spa
- California Suites Hotel
- Comfort Inn San Diego Airport At The Harbor
- Best Western Seven Seas
- Comfort Inn Sea World Area
- Hyatt Regency Mission Bay Spa and Marina
- San Diego Marriott Gaslamp Quarter
- The Sofia Hotel
- Loews Coronado Bay Resort
- Palihotel San Diego
- GreenTree Inn San Diego Mission Bay
- Mission Bay Inn San Diego
- Pendry San Diego
- The Wayfarer San Diego
- Surfer Beach Hotel
- Humphreys Half Moon Inn
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