Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Cherokee Neighborhoods for Resorts & Hotels with Spas

Featured Cherokee Resorts & Hotels with Spas

See all 298 Hotels in Cherokee
Buffalo Creek Bed & Breakfast

Buffalo Creek Bed & Breakfast

4989 West Buffalo Road, Robbinsville
3.0 out of 5.0
5.0 out of 5 (1 reviews)
B&B worthy of nice review, quiet and relaxing.We were busy with the Miata's at the Gap, however, Robin and Rob, were terrific and did everything in their power to make sure we had what we needed. They even took my 15 year old grandson on an adventurous ATV ride. He was thrilled. Back at home now, he has been telling his parents how much fun ...
  Aug 1, 2016
Comfort Suites Cherokee

Comfort Suites Cherokee

1223 Tsali Blvd, Cherokee
2.5 out of 5.0
4.2 out of 5 (127 reviews)
Clean but ready for a faceliftLobby looks great and inviting. Price is excellent for the area. However, once you walk down the halls or go up a floor or so you realize this hotel is definitely ready from a refurb. Carpets in the hallway AND rooms look dingy and worn. I will say I was very pleasantly surprised that hallways and ...
  Jul 13, 2017

$90

$90
Oak Hill on Love Lane

Oak Hill on Love Lane

224 Love Lane, Waynesville
3.5 out of 5.0
4.9 out of 5 (9 reviews)
Best experience ever!You won't want to leave this place! The home is impeccable with the most peaceful and nurturing environment someone could ask for. The owner's hospitality is genuine. I look forward to returning to this beautiful place in the mountains.
  Sep 12, 2015
Best Western Mountainbrook Inn

Best Western Mountainbrook Inn

3811 Soco Road Route 19, Maggie Valley
2.5 out of 5.0
4.0 out of 5 (90 reviews)
Reasonable hotel equidistant to Ashville and great smoky mtn Ntl park. Close to blue Ridge parkway entrance.
  Aug 29, 2017

$68

$68
The Waynesville Inn Golf Resort and Spa

The Waynesville Inn Golf Resort and Spa

176 Country Club Drive, Waynesville
3.0 out of 5.0
3.7 out of 5 (205 reviews)
Beautiful viewEnjoyed staying at this golf and country inn, they view on the seventh hole was just beautiful, the staff was very pleasant from check in to check out. Our room for a very clean and comfortable, and we very much enjoyed our stay.
  Sep 15, 2017

$95

$95
Jonathan Creek Inn and Villas

Jonathan Creek Inn and Villas

4324 Soco Rd, Maggie Valley
2.0 out of 5.0
4.5 out of 5 (94 reviews)
Weekend getawayHotel is very pleasant. Room was clean though a bit cramped. Parking is very crowded.
  Sep 17, 2017

$79

$79
Holiday Inn Express Hotel & Stes Dillsboro-Western Carolina

Holiday Inn Express Hotel & Stes Dillsboro-Western Carolina

26 Rufus Robinson Road, Sylva
2.5 out of 5.0
4.2 out of 5 (68 reviews)
hospitalities hotel in the forest Breakfast and indoor pool,and room are all awesome for guest who is planning to hike.
  Jan 6, 2017

$97

$97
Comfort Inn Maggie Valley

Comfort Inn Maggie Valley

3282 Soco Rd, Maggie Valley
2.5 out of 5.0
4.2 out of 5 (106 reviews)
Nice place, comfortable beds. Would definitely stay here again.
  Sep 18, 2017

$72

$72
Lakeview At Fontana Boutique Resort & Spa

Lakeview At Fontana Boutique Resort & Spa

171 Lakeview Lodge Dr, Bryson City
3.0 out of 5.0
4.5 out of 5 (4 reviews)
Charming! Lakeview at Fontana is a charming place to stay! It has gorgeous grounds, a lovely common area inside and out, a great breakfast buffet, and personable, attentive staff! The rooms were comfortable except that our air conditioner was quite noisy. We ended up sleeping with the window open and that ...
  Sep 8, 2016
Fontana Village Resort

Fontana Village Resort

300 Woods Roads, Fontana Dam
3.0 out of 5.0
4.0 out of 5 (54 reviews)
Nice amenities with marina and lake accessFor me, the best part of this resort were the on-site amenities which includes the two pools, the fitness center, game room, volleyball/basketball/tennis courts, putt-putt course, and more! This property also has nice biking and hiking trails. I didn't get to try out all of the amenities and scheduled ...
  Sep 8, 2017

$133

$133
Ramada Maggie Valley

Ramada Maggie Valley

4048 Soco Rd, Maggie Valley
2.0 out of 5.0
3.9 out of 5 (193 reviews)
Never been to this area before. Very peaceful and quiet
  Sep 18, 2017

$75

$75
Nantahala Cabins

Nantahala Cabins

580 Nantahala Cabins Ln, Bryson City
3.0 out of 5.0
4.6 out of 5 (15 reviews)
Nice cabins with basic and plus amenities. We love the cabin, specially the porch with the rockets and the hot tub was a nice surprise. We enjoyed the grill and the fire pit.
  Jul 14, 2017
Best Western Plus River Escape Inn & Suites

Best Western Plus River Escape Inn & Suites

248 WBI Drive, Dillsboro
2.5 out of 5.0
4.3 out of 5 (119 reviews)
Here to be with son having surgery excellent place location and ambiance
  Sep 17, 2017

$117

$117
Smoky Mountain Inn & Suites

Smoky Mountain Inn & Suites

344 Seven Clans Lane, Cherokee
2.0 out of 5.0
3.6 out of 5 (122 reviews)
Nice hotelThe only problem I had was I asked for a room with a jetted tub and gotta walking shower. Hotel fully booked so we couldn't change rooms.
  Sep 8, 2015
Cabins at Twinbrook Resort

Cabins at Twinbrook Resort

230 Twinbrook Lane, Maggie Valley
3.0 out of 5.0
4.7 out of 5 (7 reviews)
cozy cabinThe cabin was quaint and the air was cooling as we walked in. Lemon cupcakes awaited us in the fridge. It was a roomy facility with a nice bathroom. I would go there again.
  Aug 23, 2017

$159

$159
Harrah's Cherokee Casino Resort

Harrah's Cherokee Casino Resort

777 Casino Drive, Cherokee
4.0 out of 5.0
4.0 out of 5 (105 reviews)
Hotel was decentWas placed on a floor where they never vacuum the hallway rooms were excellent and clean but the foyer area and the hall were dirty with Skittles three days in a row
  Sep 20, 2017

$139

$139
Map

Recently booked Resorts & Hotels with Spas in Cherokee

Cherokee Grand Hotel
2.5 out of 5.0
Last booking: 1 hour ago
Balsam Mountain Inn
3.0 out of 5.0
Last booking: 3 hours ago
Harrah's Cherokee Casino Resort
4.0 out of 5.0
Last booking: 6 hours ago
Econo Lodge
2.0 out of 5.0
Last booking: 6 hours ago
Chestnut Tree Inn Cherokee
3.0 out of 5.0
Last booking: 6 hours ago
Comfort Suites Cherokee
2.5 out of 5.0
Last booking: 7 hours ago
Misty Mountain Ranch B&B & Cabins
2.5 out of 5.0
Last booking: 7 hours ago
A Holiday Motel
2.0 out of 5.0
Last booking: 7 hours ago
Qualla Motel
2.0 out of 5.0
Last booking: 7 hours ago

Cherokee Resorts & Spa Travel Guide

Indulge Yourself with a Cherokee Spa Vacation

You deserve the royal treatment every now and then. Take this opportunity for a weekend where you can get all your worries massaged away in Cherokee. If you are seeking for opulent lodging or reasonable alternatives, we can help you find the ideal place to stay. In fact, this area is so popular that it saw a massive swell of travelers that are making it their ultimate spot to unwind. Grab your bag and leave behind your worries to go on your stress-free holiday.

Book a Cherokee Spa Vacation that Won't Break the Bank

After you've checked-in to your Cherokee accommodations then you can check-out from your cares for a bit. Unwind and unpack your suitcase. After that you can make your first appointment to indulge yourself at a nearby spa. After you've spent the afternoon getting a therapeutic massage, rejuvenating in the sauna, or soaking in the hot tub, you can put on your explorer's cap and start uncovering the hidden gems of Cherokee. Discovering hip cafes, eclectic boutiques, or an intriguing museum can be one of the many highlights of your trip. If you're not sure where to begin, ask your hotel's concierge to get a sense for what Cherokee has to offer. There is no better source than a local to point you to an exciting evening out or to a cafe to sip a few cocktails at and socialize. Whatever you decide to do, just be sure to hang loose. Your spa weekend should be nothing but exceedingly relaxing.

Offering plenty of restful retreats and and calm locations, it's easily apparent why more and more people are choosing Cherokee as their stress-free spa getaway sanctuary.