South Carolina may have travel restrictions in place due to COVID-19.

Find out moreOpens in new tab or window

Luxury Hotels & Resorts in South Carolina

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Top Cities in South Carolina

Top South Carolina Luxury Hotels

Belmond Charleston Place

Belmond Charleston Place

5 out of 5
205 Meeting Street, Charleston, SC
The price is $329 per night from Oct 26 to Oct 27

Located in Charleston Historic District, this luxury hotel is within a 10-minute walk of Charleston City Market and Port of Charleston Cruise Terminal. Waterfront ...

4.8/5Exceptional! (983 reviews)

"We love the elegance, location and staff of this hotel. The lovely pool is a definite plus."…"

Reviewed on Sep 20, 2020

Belmond Charleston Place
Market Pavilion Hotel

Market Pavilion Hotel

4.5 out of 5
225 East Bay Street, Charleston, SC
The price is $299 per night from Oct 25 to Oct 26

This family-friendly Charleston hotel is located in the historical district, within a 5-minute walk of Port of Charleston Cruise Terminal and Charleston City ...

4.7/5Exceptional! (794 reviews)
Would definitely recommend it!!

"A super hotel - the restaurant serves great meals for room service (not cheap, but very tasty). Would recommend for sure."…"

Reviewed on Jun 4, 2020

Market Pavilion Hotel
Planters Inn

Planters Inn

4.5 out of 5
112 N Market St, Charleston, SC
The price is $285 per night from Oct 1 to Oct 2

Located in Charleston Historic District, this luxury hotel is within a 10-minute walk of Charleston City Market, St. Michael's Episcopal Church, and Dock Street ...

4.7/5Exceptional! (1,000 reviews)

"Always a favorite place for us to stay in Charleston!"…"

Reviewed on Sep 21, 2020

Planters Inn

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Ocean 22 By Hilton Grand Vacations

Ocean 22 By Hilton Grand Vacations

4.5 out of 5
2200 North Ocean Boulevard, Myrtle Beach, SC
The price is $158 per night from Oct 4 to Oct 5

Nestled on the beach, this Myrtle Beach hotel is within a 15-minute walk of The Children's Museum of South Carolina and SkyWheel Myrtle Beach. Broadway at the ...

4.7/5Exceptional! (529 reviews)

"The beachfront suite had amazing views. We didnt like that the elevators"…"

Reviewed on Sep 19, 2020

Ocean 22 By Hilton Grand Vacations
The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina

4.5 out of 5
28 Patriots Point Road, Mount Pleasant, SC
Get Rates

This family-friendly Mount Pleasant hotel is within a 15-minute walk of Patriots Point and USS Yorktown. Patriots Point Links and Patriots Point Naval and Maritime ...

4.7/5Exceptional! (492 reviews)

"Great I loved the room and service I will stay again"…"

Reviewed on Sep 7, 2020

The Beach Club at Charleston Harbor Resort and Marina
Montage Palmetto Bluff

Montage Palmetto Bluff

5 out of 5
477 Mount Pelia Road, Bluffton, SC
The price is $396 per night from Oct 26 to Oct 27

This family-friendly Bluffton resort is located on a river, 11 mi (17.7 km) from Heyward House Historic Center, and within 25 mi (40 km) of Tanger Outlets Hilton ...

4.8/5Exceptional! (86 reviews)

"Exceptional property! Spent hours both days biking on the many nature trails."…"

Reviewed on Sep 23, 2020

Montage Palmetto Bluff
Wentworth Mansion

Wentworth Mansion

5 out of 5
149 Wentworth St, Charleston, SC
The price is $398 per night from Oct 19 to Oct 20

This family-friendly Charleston hotel is located in the historical district, within a 15-minute walk of College of Charleston, Charleston City Market, and Gibbes ...

4.9/5Exceptional! (135 reviews)

"The staff were all very helpful, especially at the concierge desk. The man and Russian woman Anastasia at breakfast took excellent care of us. Bell service did a great job, too!"…"

Reviewed on Sep 9, 2020

Wentworth Mansion
Island Oasis 6 Bedroom Holiday Home

Island Oasis 6 Bedroom Holiday Home

4.5 out of 5
16 Dove St, Hilton Head Island, SC
Get Rates

Located in North Forest Beach, this luxury vacation home is within a 10-minute walk of Coligny Theater, Coligny Beach, and Coligny Plaza. South Forest Beach ...

Island Oasis 6 Bedroom Holiday Home
Low Tide Too 6 Bedroom Home

Low Tide Too 6 Bedroom Home

4.5 out of 5
4709 S Ocean Blvd, Myrtle Beach, SC
Get Rates

Located in Long Bay Estates, this luxury vacation home is within a 15-minute walk of Long Bay Beach and Myrtle Beach State Park. The Market Common is 2.3 mi ...

Low Tide Too 6 Bedroom Home
The Sanctuary at Kiawah Island Resort

The Sanctuary at Kiawah Island Resort

5 out of 5
1 Sanctuary Beach Drive, Kiawah Island, SC
The price is $435 per night from Oct 25 to Oct 26

Nestled on the beach, this East Beach resort is within 3 mi (5 km) of Osprey Point Golf Course and Beach.

4.6/5Exceptional! (8 reviews)

"Such a beautiful location and the hotel is stunning"…"

Reviewed on Mar 10, 2020

The Sanctuary at Kiawah Island Resort
Don't see what you're looking for?
We've got more Luxury Hotels. Find the right one for you.
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Pocket Guide: Luxury Hotels in South Carolina

Search for hotels in South Carolina on Expedia. You can easily find your hotels in South Carolina using one of the methods below:

  • View our selection of featured hotels in South Carolina
  • Use the map to find hotels in the South Carolina neighborhood you prefer
  • Use the filters to see hotels in a specific area of South Carolina, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in South Carolina
  • Enter your travel dates to view the best deals on hotels in South Carolina - while they last

More trip options