Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search over 1,000,000 properties worldwide and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in San Francisco

Best deal May 24 - May 26
Tonight Apr 25 - Apr 26
This weekend Apr 26 - Apr 28
Next weekend May 3 - May 5

Featured San Francisco 4 Star Hotels

See all 736 Properties in San Francisco

Estimated price for 1 night/2 adults

Hotel Zephyr
Hotel Zephyr
4.0 out of 5.0 250 Beach Street, San Francisco, CA
Free Cancellation
4.1/5 (3,969 reviews)
$159/ night for 2 guests

Continental breakfast would be nice. A lounge in rhe hotel would be nice. The room waa not facing water as we were told at booking nor were there port jole windows

Reviewed on Apr 23, 2019
Hotel Zoe Fisherman's Wharf
Hotel Zoe Fisherman's Wharf
4.0 out of 5.0 425 North Point, San Francisco, CA
Free Cancellation
4.2/5 (6,910 reviews)
$175/ night for 2 guests

The location was perfect for catching a few sights and also

Reviewed on Apr 22, 2019
Hyatt Regency San Francisco Airport
Hyatt Regency San Francisco Airport
4.0 out of 5.0 1333 Bayshore Hwy, Burlingame, CA
Free Cancellation
4.1/5 (3,835 reviews)
$109/ night for 2 guests

Service was great - food at the restaurant was pretty good

Reviewed on Apr 24, 2019
Hyatt Regency San Francisco
Hyatt Regency San Francisco
4.0 out of 5.0 5 Embarcadero Center, San Francisco, CA
Free Cancellation
4.3/5 (4,165 reviews)
$166/ night for 2 guests

Fantastic location. Very nice to have a $15 breakfast credit - a good surprise.

Reviewed on Apr 24, 2019
San Francisco Marriott Marquis
San Francisco Marriott Marquis
4.0 out of 5.0 780 Mission Street, San Francisco, CA
Free Cancellation
4.3/5 (5,025 reviews)
$169/ night for 2 guests

The service was excellent and the hotel is clean and well maintained.

Reviewed on Apr 23, 2019
Pullman San Francisco Bay
Pullman San Francisco Bay
4.0 out of 5.0 223 Twin Dolphin Dr, Redwood City, CA
Free Cancellation
4.3/5 (3,508 reviews)
$104/ night for 2 guests

The hotel was beautiful and comfortable. Very clean.

Reviewed on Apr 22, 2019
Pier 2620 Hotel Fisherman's Wharf
Pier 2620 Hotel Fisherman's Wharf
4.0 out of 5.0 2620 Jones Street, San Francisco, CA
Free Cancellation
4.2/5 (5,498 reviews)
$169/ night for 2 guests

Location, room, staff, service. Even with renovations at the lobby level the hotel excelled.

Reviewed on Apr 23, 2019
Hotel Spero
Hotel Spero
4.0 out of 5.0 405 Taylor St, San Francisco, CA
Free Cancellation
4.4/5 (898 reviews)
$139/ night for 2 guests

Great gym with weights and treadmills. Easy checkin and helpful staff when i need some directions to a business meeting in SF.

Reviewed on Apr 24, 2019
Hotel Nikko San Francisco
Hotel Nikko San Francisco
4.0 out of 5.0 222 Mason St, San Francisco, CA
Free Cancellation
4.4/5 (7,954 reviews)
$176/ night for 2 guests

Convenient location in downtown SF. expect traffic noises later in night during the weekend.

Reviewed on Apr 22, 2019
Map

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

Americas Best Value Inn-Richmond/San Francisco
2.0 out of 5.0
Last booking: 4 minutes ago
Extended Stay America Oakland - Alameda Airport
2.5 out of 5.0
Last booking: 19 minutes ago
Americas Best Value Inn & Suites SoMa
2.0 out of 5.0
Last booking: 47 minutes ago
Holiday Inn San Francisco International Airport
3.0 out of 5.0
Last booking: 1 hour ago
Villa Montes Hotel, an Ascend Hotel Collection Member
3.0 out of 5.0
Last booking: 1 hour ago
The Marina Inn on San Francisco Bay
2.5 out of 5.0
Last booking: 1 hour ago
The Westin San Francisco Airport
4.0 out of 5.0
Last booking: 1 hour ago
Bay Landing San Francisco Airport Hotel
3.0 out of 5.0
Last booking: 1 hour ago