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Treat your every desire on your upcoming break. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made San Francisco so popular in the last year. Come see what all the excitement is about. We should also mention, the hotels in this area are known for guest services, so you know you'll be well cared for during your getaway. Reserve one of our 5-star hotels in San Francisco and indulge in the finer things in life for a while. What are you waiting for?

Get a Great Deal on 5-Star Hotels in San Francisco

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Highly-rated eateries, exceptional customer care, and fabulous spa offerings are waiting for you. We have a huge number of hotels in the region, and all of them offer awesome amenities. Additionally, the hotels in this area receive fantastic marks for guest services, so you know you'll be looked after during your getaway. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling refreshed and alive? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A Swedish massage to help your cares fall away? Want to see for yourself? Then explore the 13,157 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? You're in luck. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals -- they'll be happy to sit down for a pint or a cuppa.

Your Getaway Starts Today

The results are in, and San Francisco 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Your great getaway is just a mouse-click away -- this is a great time to find 5-star hotel deals in @region! Choose one of Expedia's San Francisco 5-star hotels today and soothe yourself in complete comfort tomorrow.

Recently booked 5 Star Hotels in San Francisco

Hotel Whitcomb
3.5 out of 5.0
Last booking: 1 minute ago
Hotel Kabuki - a Joie de Vivre Boutique Hotel
4.0 out of 5.0
Last booking: 1 minute ago
JW Marriott San Francisco Union Square
4.0 out of 5.0
Last booking: 1 minute ago
San Mateo SFO Airport Hotel
2.5 out of 5.0
Last booking: 1 minute ago
InterContinental Mark Hopkins
4.0 out of 5.0
Last booking: 3 minutes ago
Axiom Hotel San Francisco
4.0 out of 5.0
Last booking: 4 minutes ago
Kimpton Sir Francis Drake Hotel
4.0 out of 5.0
Last booking: 5 minutes ago
Hilton San Francisco Airport Bayfront
4.0 out of 5.0
Last booking: 6 minutes ago
Hilton San Francisco Union Square
4.0 out of 5.0
Last booking: 7 minutes ago