The best area to stay on Edisto Island is along Palmetto Boulevard, which runs parallel to the beach and offers easy access to the ocean.Palmetto Boulevard is the main thoroughfare for visitors, providing direct access to the oceanfront. This area is characterized by a mix of vacation rentals, from cozy cottages to larger homes, many with direct beach access or ocean views. It's a convenient location for enjoying the island's natural beauty and recreational activities.Families often find this area ideal due to the abundance of rental homes, many equipped with full kitchens and multiple bedrooms, making longer stays comfortable and convenient. The proximity to the beach means easy trips for swimming, shell collecting, and enjoying the sun without needing to drive.For couples seeking a peaceful retreat, the southern end of Palmetto Boulevard, particularly near the state park, offers a more secluded and quiet experience.