A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Search Guest Houses in Florida Keys

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Check prices for these dates

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15
In one month
Nov 27 - Nov 29
In two months
Dec 25 - Dec 27

Our top choices for Florida Keys guest houses

A beach with rows of sun loungers and palm trees.

1. Ragged Edge Resort & Marina

Ragged Edge Resort & Marina
2.5 star property
Islamorada
9.6 out of 10, Exceptional, (277 reviews)
"Incredible place, ample room and everything you need to cook and to bbq."
United States
Nathalie
$126 nightly
The price is $142
Nov 1 - Nov 2
Total with taxes and fees
Ragged Edge Resort & Marina
Room

2. The Independent Inn

The Independent Inn
3.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (67 reviews)
"Dan and Emma own the property and they go out of their way to give you the best experience you can receive. They are continuously on the property, working trying to maintain and make improvements. Thoroughly enjoyed the stay."
United States
Malcolm
$163 nightly
The price is $183
Nov 2 - Nov 3
Total with taxes and fees
The Independent Inn
A tropical outdoor area with palm trees, hanging plants, and string lights.

3. Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.8 out of 10, Exceptional, (573 reviews)
"Loved our stay! I would definitely stay there again."
United States
Maricela
$199 nightly
The price is $224
Nov 3 - Nov 4
Total with taxes and fees
Douglas House - Adults Only
A green house with a white porch, a flag, and a sign advertising a property for sale.

4. L'Habitation Guest House - Adults Only

L'Habitation Guest House - Adults Only
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,003 reviews)
"Everything was amazing. Drew runs a beautiful place."
United States
Matthew
$136 nightly
The price is $153
Nov 2 - Nov 3
Total with taxes and fees
L'Habitation Guest House - Adults Only
A white building with a grey roof, surrounded by potted plants and a blue umbrella.

5. The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only
3.0 star property
Old Town Key West
8.8 out of 10, Excellent, (1,000 reviews)
"Great location and quaint courtyard vibe"
United States
Donna
$206 nightly
The price is $232
Nov 1 - Nov 2
Total with taxes and fees
The Cabana Inn Key West - Adults Only
A bathroom with a large mirror, a sink, and two towel rings.

6. Duval Inn

Duval Inn
3.0 star property
Old Town Key West
8.8 out of 10, Excellent, (844 reviews)
"Clean room and great accessibility to Duval Street"
United States
Megan
$228 nightly
The price is $257
Oct 31 - Nov 1
Total with taxes and fees
Duval Inn
A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.

7. The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,000 reviews)
"Fun apartment style living in Key West…fun little patio with coffee and continental breakfast. Make sure you look at the check in hours :) great spot makes you feel local"
United States
Justyn
$232 nightly
The price is $261
Nov 15 - Nov 16
Total with taxes and fees
The Grand Guesthouse
A two-story building with a white picket fence, palm trees, and a sign that reads 'DUVAL GARDENS.'

8. Duval Gardens - Adults Only

Duval Gardens - Adults Only
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (925 reviews)
"Great rooms and staff, the breakfast is amazing "
United States
JoAnn
$239 nightly
The price is $269
Nov 19 - Nov 20
Total with taxes and fees
Duval Gardens - Adults Only
A covered outdoor seating area with wicker chairs and a glass table, overlooking a lush garden with palm trees and a pool.

9. Curry House

Curry House
2.0 star property
Old Town Key West
7.0 out of 10, Good, (71 reviews)
"An excellent location in town for a visit. We were up on third floor great view especially from porch…tough getting up stairs w luggage. Overall a wonderful visit. Beautiful location and just antique enough! Cheers"
United States
donald
$248 nightly
The price is $279
Nov 18 - Nov 19
Total with taxes and fees
Curry House
A covered porch with wicker furniture, potted plants, and a sign for the "Office" at the Palm Hotel.

10. The Palms Hotel

The Palms Hotel
3.0 star property
Old Town Key West
9.0 out of 10, Wonderful, (1,001 reviews)
"great staff, clean place ,"
United States
mark
$202 nightly
The price is $227
Nov 1 - Nov 2
Total with taxes and fees
The Palms Hotel
A grand room with a large wooden door, a fireplace with a mantelpiece, and a chandelier.

11. Amsterdam's Curry Mansion Inn

Amsterdam's Curry Mansion Inn
3.0 star property
Key West Historic District
8.0 out of 10, Very good, (1,002 reviews)
"Great location!"
United States
carmen
$311 nightly
The price is $350
Nov 1 - Nov 2
Total with taxes and fees
Amsterdam's Curry Mansion Inn
A pool area with a blue table and chairs, surrounded by palm trees and a white building.

12. Banana's Foster Guesthouse

Banana's Foster Guesthouse
2.0 star property
Key West Historic District
8.6 out of 10, Excellent, (26 reviews)
"Perfect location and lovely place!"
United States
michael
$279 nightly
The price is $314
Nov 16 - Nov 17
Total with taxes and fees
Banana's Foster Guesthouse
A wooden deck with a hot tub, surrounded by tropical vegetation and a bungalow-style house with a sloped roof.

13. Wicker Guesthouse

Wicker Guesthouse
3.5 star property
Old Town Key West
8.6 out of 10, Excellent, (1,001 reviews)
"Great place to stay. Always love coming back here."
United States
Cheyenne
$219 nightly
The price is $246
Nov 1 - Nov 2
Total with taxes and fees
Wicker Guesthouse
A covered porch with wicker furniture, a ceiling fan, and a view of the street.

14. FLAGLER ROOM @ Inn on Fleming~ADULTS ONLY 1st Floor King w/Community Pool

FLAGLER ROOM @ Inn on Fleming~ADULTS ONLY 1st Floor King w/Community Pool
Old Town Key West
10.0 out of 10, Exceptional, (50 reviews)
"The place is very cute. The pool was perfect."
United States
Jay
$268 nightly
The price is $297
Nov 2 - Nov 3
Total with taxes and fees
FLAGLER ROOM @ Inn on Fleming~ADULTS ONLY 1st Floor King w/Community Pool
A gated entrance with lush green foliage and a white picket fence.

15. Coco Plum Inn

Coco Plum Inn
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (574 reviews)
"Location was perfect"
United States
August
$251 nightly
The price is $283
Nov 1 - Nov 2
Total with taxes and fees
Coco Plum Inn
A living room with two sofas, a coffee table, and a window with blinds.

16. HAVANA VIEJA ~ Adults Only, First Floor Queen Room w/ Community Pool!

HAVANA VIEJA ~ Adults Only, First Floor Queen Room w/ Community Pool!
Old Town Key West
9.6 out of 10, Exceptional, (173 reviews)
"One of our best vacations ever. Our room was steps from the pool and common areas. I would highly recommend staying here."
United States
Vicki L.
$262 nightly
The price is $291
Nov 30 - Dec 1
Total with taxes and fees
HAVANA VIEJA ~ Adults Only, First Floor Queen Room w/ Community Pool!
A white building with green shutters, surrounded by a white picket fence and palm trees.

17. Kona Kai Oasis

Kona Kai Oasis
3.0 star property
Old Town Key West
8.0 out of 10, Very good, (683 reviews)
"Not bad for the price . Great location!"
United States
Parker
$206 nightly
The price is $232
Nov 29 - Nov 30
Total with taxes and fees
Kona Kai Oasis
A poolside area with a covered seating area, a pool, and lush greenery.

18. NumberEleven~Charming Adult Only, 1st Lvl, 1 Bedroom, 1 Bath w/Community Pool

NumberEleven~Charming Adult Only, 1st Lvl, 1 Bedroom, 1 Bath w/Community Pool
Old Town Key West
9.8 out of 10, Exceptional, (98 reviews)
"The room and the grounds are kept spectacular. We had a great time."
United States
paul
$379 nightly
The price is $420
Nov 30 - Dec 1
Total with taxes and fees
NumberEleven~Charming Adult Only, 1st Lvl, 1 Bedroom, 1 Bath w/Community Pool
A room with a bed, a ceiling fan, and a window with blinds.

19. The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (331 reviews)
"such a lovely location. nice and quiet for a restful stay. staff was attentive to all our needs. would definitely return"
United States
christine
$337 nightly
The price is $379
Nov 29 - Nov 30
Total with taxes and fees
The Mermaid & Alligator
A swimming pool with a blue mosaic wall and a waterfall feature.

20. Colors on White

Colors on White
3.0 star property
Old Town Key West
8.0 out of 10, Very good, (494 reviews)
"Check-in was easy. Property was very dirty, does not look like they clean the floors at all.. water pressure awful. Property definitely needs some updating.."
United States
Kellie
$249 nightly
The price is $280
Nov 8 - Nov 9
Total with taxes and fees
Colors on White
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florida Keys Hotel Reviews

Islander Resort

Islander Resort

10/10 Excellent
"We had a great honeymoon at the islander. The staff was very helpful, Te was great when helping us use the amenities and Chris was the best waiter at Drift!"
Emma 4-night trip
Posted 2 hours ago
Islander Resort

Find out more about Florida Keys

Florida Keys Guest Houses information

Number of reviews
8,350
Accommodation
3 Guest Houses
Lowest Price
$142
Highest Price
$420

Frequently asked questions

What is the nightly rate for a guest house in Florida Keys?
Rates for Florida Keys guest houses vary, but travelers can find great-value prices from $142 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Florida Keys guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a Florida Keys guest house and a B&B?
A guest house in Florida Keys is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

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