Find Resorts & Hotels with Spas in Murrells Inlet, SC

Check prices for these dates

Tonight
Nov 15 - Nov 16
Tomorrow
Nov 16 - Nov 17
Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29

Our top choices for Murrells Inlet hotels with a spa

A beach view with a clear sky, palm trees, and a pool area with lounge chairs.

1. Dunes Village Resort

Dunes Village Resort
3.5 star property
Myrtle Beach
8.4 out of 10, Very good, (5,043 reviews)
  • cleanliness
    Myrtle Beach oasis boasts oceanfront relaxation with private couples' treatment rooms, aromatherapy spa services, and 3 inviting hot tubs.
$83 nightly
The price is $94
Nov 16 - Nov 17
Total with taxes and fees
Dunes Village Resort
A reception area with a blue wall, wooden shelves with products, a reception desk, and two armchairs.

2. Caribbean Resort & Villas

Caribbean Resort & Villas
3.0 star property
Myrtle Beach
7.8 out of 10, Good, (1,388 reviews)
  • cleanliness
    Relax in oceanfront splendor at this Myrtle Beach haven featuring couples spa treatments, lazy river, and 7 refreshing pools.
$109 nightly
The price is $123
Nov 16 - Nov 17
Total with taxes and fees
Caribbean Resort & Villas
A large outdoor swimming pool with multiple lanes, sun loungers, and a water slide.

3. Grand Palms Resort

Grand Palms Resort
3.0 star property
Surfside Beach
9.2 out of 10, Wonderful, (1,031 reviews)
  • cleanliness
    Rejuvenate at this tranquil resort with couples spa treatments, hot stone massages, and wellness amenities.
Grand Palms Resort
A spacious living room with a curved sectional sofa, a coffee table, and large windows offering a view of the beach.

4. Hampton Inn & Suites Myrtle Beach/Oceanfront

Hampton Inn & Suites Myrtle Beach/Oceanfront
3.0 star property
Myrtle Beach
8.4 out of 10, Very good, (1,442 reviews)
$101 nightly
The price is $114
Nov 22 - Nov 23
Total with taxes and fees
Hampton Inn & Suites Myrtle Beach/Oceanfront
A reception area with a wooden reception desk, two green chairs, and a ceiling with the word "Awakening" prominently displayed.

5. Anderson Ocean Club and Spa by Oceana Resorts

Anderson Ocean Club and Spa by Oceana Resorts
3.5 star property
Myrtle Beach
8.6 out of 10, Excellent, (3,552 reviews)
  • cleanliness
    Relax in oceanside luxury with 6 treatment rooms, daily spa services, and 2 outdoor pools for a rejuvenating escape.
$93 nightly
The price is $105
Nov 16 - Nov 17
Total with taxes and fees
Anderson Ocean Club and Spa by Oceana Resorts
An indoor swimming pool with a wooden ceiling and brick flooring, surrounded by tables and chairs.

6. Sands Ocean Club Resort

Sands Ocean Club Resort
3.0 star property
Myrtle Beach
7.6 out of 10, Good, (3,658 reviews)
  • cleanliness
    Waterfront resort offers rejuvenation with full-service spa, daily massages, and indoor/outdoor pools.
$78 nightly
The price is $86
Nov 16 - Nov 17
Total with taxes and fees
Sands Ocean Club Resort
A hotel room with two beds, a large mirror, a sink, and a glass shower enclosure.

7. North Beach Resort & Villas

North Beach Resort & Villas
4.0 star property
Windy Hill
8.8 out of 10, Excellent, (1,165 reviews)
  • cleanliness
    Unwind in a coastal retreat with 8 treatment rooms, Turkish hammam, and 5 outdoor pools at this North Myrtle Beach spa haven.
$163 nightly
The price is $183
Nov 16 - Nov 17
Total with taxes and fees
North Beach Resort & Villas
A reception desk with marble patterns, a wooden panel with a circular design, and a wall-mounted display with decorative items.

8. Marina Inn At Grande Dunes

Marina Inn At Grande Dunes
4.5 star property
Myrtle Beach
9.4 out of 10, Exceptional, (1,906 reviews)
  • cleanliness
    Escape to this waterfront retreat with a full-service spa, private beach access, and marina views for a rejuvenating coastal getaway.
$134 nightly
The price is $151
Nov 19 - Nov 20
Total with taxes and fees
Marina Inn At Grande Dunes
A hotel lobby with a carpeted floor, a reception desk, and a spa sign.

9. Marriott Myrtle Beach Resort & Spa at Grande Dunes

Marriott Myrtle Beach Resort & Spa at Grande Dunes
4.0 star property
Myrtle Beach
9.2 out of 10, Wonderful, (1,132 reviews)
  • cleanliness
    Luxurious spa sanctuary along Myrtle Beach with 14 treatment rooms, serene indoor and outdoor pools, and hot tubs for rejuvenation.
$184 nightly
The price is $208
Nov 19 - Nov 20
Total with taxes and fees
Marriott Myrtle Beach Resort & Spa at Grande Dunes
A massage therapy session in a room with a bed and a massage table.

10. Island Vista Resort

Island Vista Resort
4.0 star property
Myrtle Beach
9.2 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Oceanfront resort offers hot stone massages, body treatments, and pools for coastal rejuvenation.
$106 nightly
The price is $120
Nov 29 - Nov 30
Total with taxes and fees
Island Vista Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Murrells Inlet

Pool
Hot tub

Top Murrells Inlet Hotel Reviews

A hotel lobby with a carpeted floor, a reception desk, and a spa sign.
Marriott Myrtle Beach Resort & Spa at Grande Dunes

Marriott Myrtle Beach Resort & Spa at Grande Dunes

Marriott Myrtle Beach Resort & Spa at Grande Dunes
Myrtle Beach

10/10 Excellent

Great!
United States
Mary
Reviewed August 4, 2025
Marriott Myrtle Beach Resort & Spa at Grande Dunes

Find out more about Murrells Inlet

Top Murrells Inlet attractions for a relaxing vacation

In Murrells Inlet, travelers seeking a rejuvenating spa experience will find a wealth of activities to complement their stay. Start your day with a scenic stroll along the picturesque waterfront, where you can soak in stunning views of the marshlands and indulge in the area’s rich coastal beauty. After that, consider a leisurely round of golf at one of the championship courses nearby, offering lush greens and serene landscapes that invite relaxation. For those who enjoy the sea, embark on a tranquil boat tour to explore the surrounding waterways, where you can appreciate the local wildlife and perhaps catch a glimpse of dolphins frolicking nearby. As the sun sets, unwind with a sunset cruise that provides a unique perspective of the shoreline and an opportunity to enjoy the vibrant colors of the sky. Finally, don’t miss the chance to savor fresh, locally-sourced seafood at one of the charming waterfront restaurants, combining culinary delights with a laid-back atmosphere. After a day full of exploration and relaxation, retreat to your spa hotel, where attentive service and pampering treatments await you, ensuring every moment of your stay is as restorative as it is enjoyable.

Frequently Asked Questions

How much does a spa hotel in Murrells Inlet cost?

Enjoy staying in a spa hotel in Murrells Inlet, with plenty of hotels from $86 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.

Is it cheaper to book a spa hotel in Murrells Inlet with flights as part of a package deal?

Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it’s wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.

Are there any unique spa experiences available in Murrells Inlet?

In Murrells Inlet, you'll find several unique spa experiences, including those offered by Waccamaw Medspa, Hand & Stone Murrells Inlet, The Day Spa at Wachesaw, and Celestial Spa.

Waccamaw Medspa stands out with its signature S'more Facial, which uses a marshmallow mask and a chocolate lip mask for a truly indulgent skincare experience. They also provide advanced laser rejuvenation treatments and seasonal massage specials, such as the "Fall Into Relaxation Massage."

Hand & Stone Murrells Inlet offers a diverse selection of specialized massages, including Swedish, Himalayan Salt, Sports, Deep Tissue, Oncology, and Prenatal options. Their advanced skincare services feature treatments like the Diamond Glow facial, NuFACE microcurrent facial, and LED Phototherapy facial, utilizing award-winning skincare lines.

The Day Spa at Wachesaw is a local favorite, known for its cozy atmosphere and personalized therapeutic massages, facials, and full-service salon treatments. They focus on a holistic approach to wellness, tailoring services to individual needs for mind, body, and soul balance.

Celestial Spa specializes in massage therapy, medicupping, premier facials, waxing, and body treatments.

Can I cancel my spa hotel reservation on Expedia?

Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Murrells Inlet for you.

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