This culture and arts hub in Key West Historic District comes recommended by travelers, so be sure to put it on your to-do list. Don't stop there, though. There are a lot more spots ready for you to check out after San Carlos Institute - Casa Cuba. Ernest Hemingway Home and Museum, Audubon House and Tropical Gardens, and Mallory Square are not far away.

Plan a trip to see San Carlos Institute - Casa Cuba

Price found within the past 48 hours. Click for updated prices.

The Perry Hotel & Marina Key West

Save 100% on your flight

$561

per person

Oct 27 - Nov 1

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Key West (EYW)

9.4/10 Exceptional! (1,068 reviews)

easy access to fishing, shuttle to key west, great rooms

Reviewed on Aug 20, 2025

Lighthouse Hotel - Key West Historic Inns

Old Town Key West

Save 100% on your flight

$729

per person

Oct 27 - Nov 1

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Key West (EYW)

9/10 Wonderful! (775 reviews)

The property is cute with its own unique vibe. Our room did smell a bit musty, but it’s damp south Florida…so I took that with a grain of salt. There was some mold in our bathroom grout also, but I wasn’t in the mood to complain about something so petty. One thing I will rave about was Jefferson, he was working at the pool bar and not only was he a joy to talk to, he made a great drink!

Reviewed on Aug 19, 2025

Douglas House

Old Town Key West

Save 100% on your flight

$1,015

per person

Oct 27 - Nov 1

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Key West (EYW)

9.6/10 Exceptional! (155 reviews)

This property is one block off of Duval Street and it has a quiet serene pool with lush Gardens around it. It was truly magnificent.

Reviewed on Aug 6, 2025

Browse tours and tickets to explore San Carlos Institute - Casa Cuba

Tours & day trips

See all 159 activities

Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar

History & culture

See all 54 activities

Key West Day Trip & Glass Bottom-Boat Tour from Miami

Free cancellation available

Wildlife & nature

See all 48 activities

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

Free cancellation available

Private & custom tours

See all 36 activities

Dry Tortugas National Park Day Trip by Luxury Boat: Axopar 37 XC

Free cancellation available

Adventure & outdoor

See all 17 activities

Key West Half-Day Fishing Charter

Free cancellation available

Popular places to visit

Jackson Square

You can learn about the history of Key West with a stop at Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.

Duval Street

Along one of the southernmost streets in the continental U.S., enjoy a lively area filled with shops, pubs, restaurants and lots of sidewalk acts and vendors.

Oldest House Museum and Garden

With its period décor and vintage documents, South Florida’s oldest house provides an impression of life in the Florida Keys archipelago in the 19th century

22 room mansion all decked out for Valentine’s Day. Home to Florida’s 1st millionaire.

Curry Mansion Museum

You can spend time studying the exhibits at Curry Mansion Museum during your trip to Key West. Stroll along the area's beautiful beaches or experience its lively festivals.