Florida Keys National Marine Sanctuary Tours

Florida Keys National Marine Sanctuary

Florida Keys National Marine Sanctuary is the perfect place kick off your day in Key West. This protected ocean area is recommended by fellow travelers, but it isn't the only thing to do here. Pencil in time for other sights like Ernest Hemingway Home and Museum, Audubon House and Tropical Gardens, and Mallory Square to make the most of what's on offer in the area.

Plan a trip to see Florida Keys National Marine Sanctuary

Price found within the past 48 hours. Click for updated prices.
Bishop Hotel Key West

Bishop Hotel Key West

4 out of 5
Old Town Key West
Save 100% on your flight
Price was $1,631, price is now $1,007 per person
$1,007
per person
Nov 12 - Nov 19
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Key West (EYW)
9.8/10 Exceptional! (220 reviews)
The Bishop Hotel is an amazing place to stay. They make you feel special from the moment you check-in. All of the staff are extremely friendly, helpful, and want you to have the best time. I really loved the security of the main door, no worry about anyone other than guests entering. The front desk has 24/7 coverage, great feature. Our room had a balcony, it was great to take a break and just relax and watch the day to day of Fleming St. Be sure to take your phone with you in case your balcony door is locked. Yes, it does happen. They are quick to rescue you. We were there in the off season, so it was a little quieter than normal, but we didn't mind. Highly recommend the Bishop, you won't be disappointed.

Reviewed on Aug 25, 2025

Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

4 out of 5
Save 100% on your flight
Price was $1,952, price is now $1,151 per person
$1,151
per person
Nov 2 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Key West (EYW)
9/10 Wonderful! (1,722 reviews)
Fantastic staff, always smiling. Great amenities, super clean, fantastic location.

Reviewed on Aug 25, 2025

Lighthouse Hotel - Key West Historic Inns

Lighthouse Hotel - Key West Historic Inns

3.5 out of 5
Old Town Key West
Save 100% on your flight
Price was $2,211, price is now $1,351 per person
$1,351
per person
Nov 2 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Key West (EYW)
9/10 Wonderful! (775 reviews)
it’s a great location but quiet. Love the free breakfast, pool and rooms! staff was great too!

Reviewed on Aug 23, 2025

Browse tours and tickets to explore Florida Keys National Marine Sanctuary

Tours & day trips

See all 158 activities
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar

Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar

Activity duration is 16 hours and 30 minutes
7.8 out of 10 with 15 reviews
The previous price was $79 and current price is $57 per adult
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open barOpens in new tab

History & culture

See all 52 activities
Key West Day Trip & Glass Bottom-Boat Tour from Miami

Key West Day Trip & Glass Bottom-Boat Tour from Miami

Activity duration is 12 hours
5.0 out of 10 with 27 reviews
Free cancellation available
Price is $129 per adult
Key West Day Trip & Glass Bottom-Boat Tour from MiamiOpens in new tab

Wildlife & nature

See all 49 activities
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

Activity duration is 3 hours
9.2 out of 10 with 130 reviews
Free cancellation available
Price is $50 per adult
Key West Morning Snorkel Adventure with Bottomless Mimosas & BreakfastOpens in new tab

Private & custom tours

See all 37 activities
Dry Tortugas National Park Day Trip by Luxury Boat: Axopar 37 XC

Dry Tortugas National Park Day Trip by Luxury Boat: Axopar 37 XC

Activity duration is 8 hours
Free cancellation available
Price is $3,864 per adult*
Dry Tortugas National Park Day Trip by Luxury Boat: Axopar 37 XCOpens in new tab

Adventure & outdoor

See all 17 activities
Key West Half-Day Fishing Charter

Key West Half-Day Fishing Charter

Activity duration is 5 hours
9.2 out of 10 with 14 reviews
Free cancellation available
Price is $102 per adult
Key West Half-Day Fishing CharterOpens in new tab

Popular places to visit

Florida Keys Eco - Discovery Center featuring marine life, signage and interior views

Florida Keys Eco - Discovery Center

Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.

Florida Keys Eco - Discovery Center
Fort Zachary Taylor Historic State Park featuring a beach and general coastal views

Fort Zachary Taylor Historic State Park

The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.

Fort Zachary Taylor Historic State Park
Really cool sign that show how far away you are from different places. One of the most beautiful beaches I've ever been to. #BVStrove

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.

Truman Beach
Jackson Square featuring heritage architecture and an administrative buidling

Jackson Square

You can learn about the history of Key West with a stop at Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.

Jackson Square
Harry S. Truman Little White House showing a house

Harry S. Truman Little White House

Visit the winter home of President Harry S. Truman to see where some of America’s most important post-war decisions were made.

Harry S. Truman Little White House
Key West Lighthouse and Keeper\'s Quarters Museum which includes a lighthouse as well as a small group of people

Key West Lighthouse and Keeper's Quarters Museum

Climb to the top of this historic lighthouse for unparalleled photo opportunities and then visit the former home of Key West’s lighthouse keepers.

Key West Lighthouse and Keeper's Quarters Museum

Best Lodging Options Near Florida Keys National Marine Sanctuary

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
Southernmost Beach Resort and Guesthouses
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

4 out of 5
601 Front St, Key West, FL
Hyatt Centric Key West Resort and Spa
Pier House Resort & Spa

Pier House Resort & Spa

4 out of 5
1 Duval St, Key West, FL
Pier House Resort & Spa
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street, Key West, FL
The Southernmost Inn - Adults Only
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

4 out of 5
430 Duval St, Key West, FL
La Concha Key West, Autograph Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

4 out of 5
1500 Reynolds Street, Key West, FL
Casa Marina Key West, Curio Collection by Hilton
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

4 out of 5
245 Front Street, Key West, FL
Opal Key Resort & Marina, Key West
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street, Key West, FL
The Reach Key West, Curio Collection by Hilton
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

3 out of 5
413 Applerouth Lane, Key West, FL
The Cabana Inn Key West - Adults Only
See all 2,675 properties in Florida Keys National Marine Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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