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Cool people having fun on the water slide with friends and familiy in the aqua fun park glides playing happy and water splashes are all over. Blue sky background looks amazing sunlight

Villas in Santa Fe

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Check prices for these dates

Check prices for these dates, December 12 – 13, 2026

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Our top choices for Santa Fe villas

1. Luxe Villa Close to Galveston, Kemah, NASA & Houston

Exterior

2. Waterfront Retreat Getaway with Gameroom Firepit Fishing Kayaks

A covered outdoor area with a hammock, a wooden table, and a skateboard ramp.

3. Made for Group Getaways, Family Escapes and Memorable Stays with Space to Relax, Play and Connect

A large brick house with a curved driveway, a front porch, and a well-maintained lawn.

4. Private Mansion Retreat Basketball Court and More

Room

5. Lakeside Luxury: Recently Renovated in lovely Kemah

A two-story house with a covered porch and a staircase leading to a balcony.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top reviews in Santa Fe

SpringHill Suites by Marriott Texas City

An outdoor seating area with a fire pit, chairs, and a modern architectural design.

Home2 Suites by Hilton Texas City Houston

A hotel with a modern facade, a covered outdoor seating area, and a parking lot.

Hampton Inn & Suites Houston/League City

A Hampton Inn & Suites hotel with a clear entrance, a covered walkway, and a well-lit facade.

La Quinta Inn & Suites by Wyndham Texas City I 45

A hotel with a modern design, featuring a prominent 'La Quinta' sign and a covered entrance.

Holiday Inn Express Hotel & Suites Houston-Alvin by IHG

A Holiday Inn Express & Suites hotel with a covered entrance and a stone facade.

SureStay Plus Hotel by Best Western Alvin

A swimming pool with a hot tub, surrounded by a fence, palm trees, and outdoor seating.

Americas Best Value Inn & Suites Alvin Houston

A gas station with a covered entrance, a large white planter, and a truck parked outside.

Best Western Texas City I-45

A hotel with a modern facade, multiple windows, and a parking lot with several cars.

Candlewood Suites League City by IHG

A hotel with a modern facade, multiple windows, and a prominent signage.

Courtyard by Marriott Houston NASA/Clear Lake

A Courtyard Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

Tru by Hilton Houston Webster NASA

A modern hotel building with a sign reading "tru by Hilton" and a well-lit entrance.

Candlewood Suites Hotel Texas City by IHG

A multi-story hotel with a prominent "Candlewood Suites" sign, featuring a modern design with a mix of neutral and red tones.

Hampton Inn & Suites La Porte

A Hampton Inn & Suites hotel with a covered entrance, a blue delivery van, and a clear sky.

Home2 Suites by Hilton Houston Webster

A modern hotel with a prominent 'HOME' sign, a flagpole with an American flag, and a well-lit entrance area.

Residence Inn by Marriott Galveston Island

A multi-story hotel with a modern design, featuring a central entrance, a parking area, and a landscaped courtyard.

Frequently Asked Questions

Why book your villa in Santa Fe with Expedia?

With Expedia, it's easy to find your ideal villa in Santa Fe. Traveling with the kids? Take advantage of our filters to search for stays with amenities like free WiFi. If you have a set budget, decide on how much you're willing to spend and the star rating of the property. We'll help you find the right fit in tune with your taste and style.

How can I find cheap villas in Santa Fe?

Expedia is here to help you easily locate cheap villas in Santa Fe. Simply use our filter tool to choose star rating, amenities and budget to refine your search and find an amazing place to stay in just a few clicks.

What is there to do near my villa in Santa Fe?

Once you've unpacked and settled in, get out and explore the fun things Santa Fe has for you to experience. Haak Vineyards and Winery is a popular attraction to add to your to-do list.

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