Title: Top 10 Hotels in Sikeston, MO from $66 - Competitive Prices | Expedia.com [Sikeston Travel Guide](https://expedia.com/Sikeston.dx6058766)[Vacation Rentals in Sikeston](https://expedia.com/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.com/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Car Rentals in Sikeston](https://expedia.com/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.com/Sikeston.d6058766.Destination-Travel-Guides) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Sikeston Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=PETS) Pool [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=POOL) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=HOT_TUB) Cabin [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&lodging=CABIN) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&travelerType=family_friendly) Waterpark [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&amenities=WATER_PARK) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&lodging=APARTMENT) Cottage [](https://www.expedia.com/Hotel-Search?destination=Sikeston%2C+Missouri%2C+United+States+of+America®ionId=6058766&latLong=36.877819%2C-89.589561&adults=2&startDate=2026-02-20&d1=2026-02-20&endDate=2026-02-22&d2=2026-02-22&lodging=COTTAGE) ## Check prices for these dates Tonight [Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=6058766&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=6058766&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=6058766&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6058766&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Sikeston hotels ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/95135562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1,001 reviews) "As always it was a perfect visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $89 nightly $103 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-c8905780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/de7767c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.com/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.2/10 Wonderful (12 reviews) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott $144 nightly $163 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/432f7137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (474 reviews) "Great place for an overnight stay. I will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenny $98 nightly $110 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/c790aa73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/e959f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.2/10 Wonderful (55 reviews) "Clean rooms great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) IRA $101 nightly $114 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (447 reviews) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney $100 nightly $113 total Feb 13 - Feb 14 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/a2f06e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/945fac08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/d0c3544f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston [](https://www.expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) Sikeston 9.4/10 Exceptional (1,002 reviews) "Rooms were very clean and comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lydia [](https://www.expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston I-55 [](https://www.expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very Good (1,003 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles $85 nightly $97 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/594efec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very Good (735 reviews) "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky $58 nightly $67 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/4da73ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/1fa29b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/07d69819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7657c6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 [](https://www.expedia.com/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) Sikeston 8.4/10 Very Good (286 reviews) "The hotel was very clean, beds were comfortable, and staff was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) aileen $86 nightly $98 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/717baff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1,001 reviews) "Everything was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $68 nightly $78 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/55187aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) Sikeston 6.8/10 (591 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Misty $59 nightly $68 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/3798eaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.6/10 (122 reviews) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew $54 nightly $61 total Feb 7 - Feb 8 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/db8c9491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1,002 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly $100 nightly $113 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/84598bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/ffb58563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible (Sofa Sleeper, Tub, 2 Rooms) | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/0f190cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,004 reviews) "Awesome stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breckin $90 nightly $102 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jackpot Suite | Living area | LED TV, Netflix, Hulu, first-run movies](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/e87009c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room | Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (498 reviews) "The room was clean and I was able to check in a bit early." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara $104 nightly $118 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/c7d69739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown [](https://www.expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (486 reviews) "Very nice hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angie $125 nightly $142 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/182edc95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature) | Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,000 reviews) "Breakfast was very good and staff was extremely friendly and rooms were very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rex $95 nightly $107 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d3cfa5fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/966bc5a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d18ea228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/665a33a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn By Hilton Dexter [](https://www.expedia.com/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) Dexter 10/10 Exceptional (10 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $106 nightly $119 total Feb 13 - Feb 14 Total with taxes and fees [](https://www.expedia.com/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/75079b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/c3df8884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG [](https://www.expedia.com/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) Cape Girardeau 8.2/10 Very Good (894 reviews) "Room was clean and spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George $80 nightly $96 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/e6e29f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/051de21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/81fbb6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (790 reviews) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina $106 nightly $119 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21®ionId=6058766&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels.d6058766.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSikeston-Hotels.d6058766.Travel-Guide-Hotels) ## Stay near popular Sikeston attractions ### City of Miner Convention Center This versatile 16,000-square-foot venue in Miner, Missouri hosts conferences, weddings, and community gatherings. Modern meeting rooms and a commercial kitchen make it ideal for various events. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=818566100963352576) ### Sikeston Depot Museum 3.8/5 (33 reviews) Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6305602) ### Central Park 3.8/5 (36 reviews) Central Park offers a peaceful retreat with playgrounds and open spaces for Sikeston families. Bring a blanket for a relaxing picnic or watch children enjoy the recreational facilities. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6305608) ## Sikeston and related destinations - Sikeston - Florence - Los Banos - Lima Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August. [See all hotels in Sikeston](https://www.expedia.com/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&adults=2®ionId=6058766) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=900&h=599&p=1&q=high) ## Top Sikeston Hotel Reviews ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The room was great. The facility was excellent. The people were excellent. Definitely going back." [](https://expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Room was very clean. Staff was very knowledgeable and courteous. Excellent staff in every department. " [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Good food " [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "The hotel was so nice! We planned this trip for my husbands 40th birthday, and I called ahead to see if they did anything for birthdays and they gave us a complementary upgrade on our room. I was taken back on that and thought it was so kind and generous. I wasn’t expecting that - I would have been fine with some cookies and a sign that said happy birthday! We really appreciate everyone and their generosity for us. We definitely will be staying again!!" [](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 10/10 Excellent "Clean rooms great staff" [](https://expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean room and shower, ruffled hotel toilet paper, dinner buffet, breakfast buffet, hot tub and pool. And pets are welcome. Great service and great value. " [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Great breakfast. Clean room Quiet" [](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." [](https://expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Yes everything was great" [](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ## More cheap stays in Sikeston ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr Sikeston MO $68 nightly $78 total Feb 8 - Feb 9 Total with taxes and fees 7.2/10 Good! (1,001 reviews) [](https://expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy Cape Girardeau MO $72 nightly $81 total Feb 11 - Feb 12 Total with taxes and fees 9/10 Wonderful! (1,001 reviews) [](https://expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Candlewood Suites Cape Girardeau by IHG 485 S Mount Auburn Rd Cape Girardeau MO $80 nightly $96 total Feb 22 - Feb 23 Total with taxes and fees 8/10 Very Good! (894 reviews) [](https://expedia.com/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street Cape Girardeau MO $95 nightly $107 total Feb 22 - Feb 23 Total with taxes and fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO $98 nightly $110 total Feb 23 - Feb 24 Total with taxes and fees 8.8/10 Excellent! (474 reviews) [](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St Cape Girardeau MO [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F20%2F2026&endDate=2%2F21%2F2026&selected=40113&PinnedHotelID=40113&HadPinnedHotel=true®ionId=6058766) 8.8/10 Excellent! (1,001 reviews) [](https://expedia.com/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ## Hotels in Sikeston with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 3 properties [](https://expedia.com/4Star-Sikeston-Hotels.s40-0-d6058766.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 15 properties [](https://expedia.com/3Star-Sikeston-Hotels.s30-0-d6058766.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 67 properties [](https://expedia.com/2Star-Sikeston-Hotels.s20-0-d6058766.Travel-Guide-Filter-Hotels) ## Price trends for hotels in Sikeston | Less expensive | More expensive | This month | Next month | | -------------- | -------------- | ---------- | ---------- | | December | July | $84 | $81 | | Month | Price | | --------- | ----- | | January | $86 | | February | $84 | | March | $81 | | April | $96 | | May | $95 | | June | $96 | | July | $98 | | August | $93 | | September | $96 | | October | $93 | | November | $85 | | December | $70 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Sikeston. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Find out more about Sikeston ### Top reasons to visit Sikeston - **Outdoor Adventures:** Sikeston offers a variety of outdoor activities, including scenic parks and recreational areas perfect for family outings or romantic getaways. - **Cultural Experiences:** Immerse yourself in local culture by visiting attractions like the Sikeston Depot and enjoying live entertainment at urban parks. - **Delicious Local Cuisine:** Indulge in the region's culinary delights, showcasing the warm hospitality of Sikeston's dining scene. - **Convenient Accommodations:** Choose from a range of comfortable lodging options, including pet-friendly hotels and spacious suites. - **Charming Small-Town Atmosphere:** Experience the friendly vibe of Sikeston, making every visit memorable and inviting. ### Find great hotels in Sikeston Discover a variety of accommodation options in Sikeston, Missouri, where comfort meets convenience. From pet-friendly hotels to welcoming motels, there's something for every traveler. Whether you're seeking a business-themed stay or a relaxing escape, Sikeston offers popular choices like the Hampton Inn and spacious suites. Enjoy a memorable vacation experience tailored to your needs in this charming town. - **[Days Inn and Suites by Wyndham Sikeston: ](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)** Experience comfort and convenience at Days Inn and Suites by Wyndham Sikeston, a pet-friendly hotel designed for business travelers. This property features multiple meeting rooms, making it ideal for corporate stays or events. With a pet-friendly policy that allows dogs and cats, your furry companions can join you on your journey. Guests appreciate the welcoming atmosphere and the dedicated services tailored for business needs. Whether you’re here for work or leisure, this hotel provides a relaxing retreat in Sikeston. - **Drury Inn & Suites Sikeston, MO:** Offering a blend of comfort and inclusivity, Drury Inn & Suites Sikeston, MO is an excellent choice for those seeking a welcoming environment. This 3-star hotel caters to both business and leisure travelers with its multiple meeting rooms and a fully equipped business center. The property stands out for its LGBTQIA-friendly policies and pet-friendly options, ensuring all guests feel at home. With a commitment to superior service and a warm atmosphere, it's an ideal spot for a memorable stay in Sikeston. - **[Best Western Plus Sikeston: ](https://www.expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)** Best Western Plus Sikeston is a fantastic option for travelers looking for a pet-friendly experience. This hotel welcomes pets, allowing you to bring your furry friends along for the adventure. Guests enjoy a comfortable stay with easy access to local attractions and amenities that cater to both leisure and business needs. The inviting atmosphere and attentive staff make it a popular choice among visitors, ensuring a pleasant and hassle-free experience in Sikeston. ### Where to stay in and around Sikeston Discover the charm of Sikeston, Missouri, a delightful small town perfect for outdoor enthusiasts and romantic getaways. Enjoy family-friendly activities and explore the friendly atmosphere of the city. With convenient access to nearby regions, you can experience scenic excursions and relaxing moments in nature. Don't miss the chance to savor local cuisine and immerse yourself in the warm hospitality that makes Sikeston a memorable destination for every traveler. - **[Miner: ](https://www.expedia.com/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels)** Nestled near Sikeston, Miner is a quaint village that offers a delightful blend of outdoor activities and family-friendly experiences. The area is particularly vibrant during January and the summer months of June and July, attracting visitors looking to enjoy its scenic beauty and recreational options. Outdoor enthusiasts can explore local campgrounds and parks, while the charming shops provide a taste of small-town life. Notable nearby attractions include a beautiful lake and a national state park, making Miner an ideal spot for those seeking a peaceful retreat amidst nature. - **[Bertrand: ](https://www.expedia.com/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels)** Located a mere 8 miles from Sikeston, Bertrand is a welcoming city that caters to adventure seekers and families alike. Visitors often find themselves drawn to the area during peak travel months like April and August when outdoor activities abound. Explore the stunning nature reserves and lakes in the vicinity, or visit the informative visitor center to learn more about the local flora and fauna. Bertrand’s laid-back atmosphere and beautiful landscapes make it a perfect getaway for those looking to connect with nature and indulge in outdoor fun. - **[Matthews: ](https://www.expedia.com/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels)** Also located 8 miles from Sikeston, Matthews is a charming city known for its stunning scenery and outdoor adventures. The summer months from June to August see an influx of visitors eager to explore the local national state park and lakes, which provide ample opportunities for hiking, fishing, and enjoying the great outdoors. The city also boasts a museum that offers insights into the region's history and culture. With its mix of natural beauty and cultural experiences, Matthews is a fantastic destination for those seeking both adventure and relaxation. ### Things to do near Sikeston Sikeston offers a charming blend of outdoor activities and scenic beauty, perfect for a romantic getaway. Visitors can enjoy a variety of attractions, including a recreational area and an arena entertainment facility. Don't miss the chance to experience live entertainment, which adds a vibrant touch to your stay. Whether you're looking to relax or explore, Sikeston has something for everyone to enjoy. **Shopping** In Sikeston, visit the Sikeston Factory Outlet Stores for great deals on popular brands. If you're up for a drive, head to Cape Girardeau's West Park Mall, about 20 miles away, where you'll find a diverse selection of shops and eateries to enhance your shopping experience. **Recreation** [eDen Spa & Salon](https://www.expedia.com/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels) offers a rejuvenating body treatment experience, located 29 miles from Sikeston. With a focus on wellness and relaxation, this spa provides a tranquil atmosphere for unwinding and indulging in various spa services, promoting both physical and mental well-being. **Adventure** In Sikeston, explore the nearby Mississippi River for kayaking and fishing adventures. Visit the Sikeston Depot Museum for a glimpse into local history, and don't miss the famous Lambert's Cafe, where you can enjoy a unique dining experience with throwed rolls that add to the fun. **Nightlife** Sikeston offers a cozy nightlife vibe, with venues like the Sikeston Jaycee Bootheel Rodeo, where you can enjoy live music and local events. The Redbird Express is perfect for a laid-back evening with drinks and good company, making it a great spot to unwind after a day of exploring. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Sikeston To save money on your trip to Sikeston, consider visiting between November and January when hotel prices are lower. Tuesdays are typically the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare room rates and find deals by filtering prices from lowest to highest. You can further save by bundling your hotel, flights, and activities through Expedia’s package options. Joining the One Key membership program provides access to exclusive discounts and OneKeyCash for future stays, making your travel more budget-friendly. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Sikeston are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Sikeston is Tuesday. The most expensive day to stay in Sikeston is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to refine your options based on your budget, desired location, and preferred hotel style. To find the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your Sikeston hotel reservation with your flights and activities through an Expedia package. - **Become a One Key member:** Join [Expedia's One Key membership](https://www.expedia.com/welcome-one-key) program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels. ### Find the best attractions in and around Sikeston Sikeston, Missouri, offers a delightful blend of outdoor adventures and cultural experiences, perfect for romantic getaways and family trips. Explore local attractions like the Sikeston Depot and Sikeston Park, or immerse yourself in the art scene and events at various urban parks and conference venues. Whether you're seeking scenic views or engaging cultural activities, Sikeston promises a memorable visit filled with diverse experiences. - **[Sikeston Depot Museum: ](https://www.expedia.com/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels)** Immerse yourself in local culture at the Sikeston Depot Museum. This art museum showcases the rich history and artistic expressions of the region, offering a deep dive into the community's heritage and creativity. - **[Central Park: ](https://www.expedia.com/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels)** Enjoy a family-friendly atmosphere at Central Park, where you can relax outdoors amidst beautiful landscapes. It's the perfect spot for a leisurely stroll, a picnic, or just soaking up the vibrant city vibes with loved ones. - **[Front Street Studio & Art Gallery: ](https://www.expedia.com/Front-Street-Studio-Art-Gallery-Hotels.0-l553248621532655753-0.Travel-Guide-Filter-Hotels)** Located 9 miles away, this art gallery is a haven for culture enthusiasts. Explore unique artworks and exhibits that reflect the local art scene, providing an inspiring experience for all visitors. ### Best time to go to Sikeston The best time to visit Sikeston can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Sikeston falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Sikeston falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 36.0°F (2.2°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | February | 39.2°F (4.0°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | March | 49.5°F (9.7°C) | Light Rain | Mostly Sunny | Average | Average | | April | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | June | 77.2°F (25.1°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | July | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 77.5°F (25.3°C) | Light Rain | Mostly Sunny | Average | Average | | September | 72.1°F (22.3°C) | Light Rain | Mostly Sunny | Average | Average | | October | 60.8°F (16.0°C) | Light Rain | Mostly Sunny | Average | Average | | November | 48.6°F (9.2°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 41.2°F (5.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Sikeston When visiting Sikeston, Missouri, you can fly into several nearby airports. Paducah, KY ([PAH](https://www.expedia.com/Barkley-Regional-Airport-Hotels.0-aPAH-0.Travel-Guide-Filter-Hotels)\-Barkley Regional) is 47 miles away, with hotel options like [The Respite Bed and Breakfast](https://www.expedia.com/Paducah-Hotels-The-Respite-Bed-And-Breakfast.h44452446.Hotel-Information) (4.5-star, 9 miles away) and [Harrah's Metropolis Hotel & Casino](https://www.expedia.com/Metropolis-Hotels-Harrahs-Metropolis-Hotel-Casino.h1598928.Hotel-Information) (3.5-star, 6 miles away). Cape Girardeau, MO ([CGI](https://www.expedia.com/Cape-Girardeau-Municipal-Airport-Hotels.0-aCGI-0.Travel-Guide-Filter-Hotels)\-Cape Girardeau Municipal) is located 24 miles from Sikeston, featuring hotels such as [Drury Plaza Hotel Cape Girardeau Conference Center](https://www.expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) (3-star, 6 miles away) and [Courtyard by Marriott Cape Girardeau Downtown](https://www.expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) (3-star, 6 miles away). Cairo, IL ([CIR](https://www.expedia.com/Cairo-Regional-Airport-Hotels.0-aCIR-0.Travel-Guide-Filter-Hotels)\-Cairo Regional) is also 24 miles away, with nearby accommodations like [Quality Inn Cairo I-57](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) (2 miles away) and [Super 8 by Wyndham Charleston/Sikeston East MO](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) (11 miles away). ## Frequently asked questions ### What is the best area to stay in Sikeston? > This central area is the commercial hub of Sikeston and offers the most convenient access to dining and shopping options. You'll find a concentration of hotels, restaurants, and retail establishments along this main thoroughfare, making it easy to find what you need without extensive travel. It's a practical choice for travelers looking for convenience and accessibility. > > > For solo travelers or couples passing through, staying in this area offers easy access to local eateries and provides a good base for exploring the town's amenities. ### What are the best hotels in Sikeston that travelers recommend? > The 3-star Hampton Inn Sikeston, with an excellent 9.0 rating, offers a complimentary continental breakfast and features an indoor pool and fitness facilities. Guests consistently praise its great breakfast and nice, clean rooms. It is conveniently located about one mile from Central Park. > > > Another highly recommended option is the 3-star Holiday Inn Express & Suites Sikeston Southwest by IHG, rated 8.6\. This hotel also provides a free continental breakfast and has an indoor pool and accessible fitness facilities. Travelers frequently mention the great breakfast, good rooms, and friendly staff. It is situated approximately 0.9 miles from Central Park. ### What are the best family hotels in Sikeston? > The 3-star Drury Inn & Suites Sikeston, MO, boasts an impressive 9.4 rating and is frequently praised for its comfortable and clean rooms, as well as its excellent and friendly staff. Families will appreciate the complimentary buffet breakfast and the availability of free cribs and sofa beds. > > > Another excellent choice is the Pear Tree Inn Sikeston, also with a 9.4 rating. This hotel offers connecting rooms, which are ideal for families, and provides free cribs upon request. Guests consistently highlight the friendly and helpful staff, along with the good, complimentary breakfast. > > > The [Fairfield Inn & Suites by Marriott Sikeston](https://www.expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information), rated 9.2, is another great option, featuring a pool and complimentary buffet breakfast. It's conveniently located just 1.2 miles from Central Park. > > > The [Hampton Inn Sikeston](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information), with a 9.0 rating, offers a pool, free continental breakfast, and free self-parking. It is also close to Central Park, just 1.0 mile away. > > > Lastly, the 3-star [TownePlace Suites by Marriott Sikeston](https://www.expedia.com/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information), rated 9.0, provides connecting rooms, sofa beds, and travel cribs, along with a complimentary self-serve breakfast. This hotel is also located 1.2 miles from Central Park. Find more [child-friendly accommodations in Sikeston](https://www.expedia.com/Sikeston-Hotels-Family-Hotel.0-0-d6058766-tFamilyHotel.Travel-Guide-Filter-Hotels) ### What hotels in Sikeston offer free breakfast? > The Pear Tree Inn Sikeston, with a 9.4 rating, provides a free breakfast that guests describe as good. The hotel also features free WiFi and comfortable, clean rooms. > > > The 3-star Drury Inn & Suites Sikeston, MO, also rated 9.4, offers a great free buffet breakfast. Guests frequently mention the comfortable and clean rooms, as well as the excellent and friendly staff. Its location is also noted as superb and convenient. > > > The Hampton Inn Sikeston, with a 9.0 rating, offers a great continental breakfast. This hotel is located approximately 1.0 mile from Central Park and provides free self-parking and free WiFi. > > > The Holiday Inn Express & Suites Sikeston Southwest by IHG, rated 8.6, provides a great continental breakfast. It is conveniently located about 0.9 miles from Central Park and offers complimentary self-parking and free WiFi. > > > The Best Western Plus Sikeston, with an 8.4 rating, includes a great full breakfast. Guests appreciate the comfortable and clean rooms, the friendly staff, and the good value. Find more [hotels with free breakfast in Sikeston](https://www.expedia.com/Sikeston-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d6058766-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels) ### What are the top pet-friendly hotels in Sikeston? > The 3-star Drury Inn & Suites Sikeston, MO, with an excellent 9.4 rating, warmly welcomes pets. Guests frequently praise the free buffet breakfast, comfortable and clean rooms, and the excellent, friendly staff. Its convenient location is also a frequent highlight. > > > Another highly-rated option is the Pear Tree Inn Sikeston, also boasting an impressive 9.4 rating. This hotel allows both dogs and cats and offers a complimentary breakfast. Guests consistently mention the comfortable and clean rooms, as well as the friendly and helpful service. See more [pet-friendly hotels in Sikeston](https://www.expedia.com/Sikeston-Hotels-Pet-Friendly-Hotel.0-0-d6058766-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) ### What are the best budget hotels in Sikeston? > The 3-star Drury Inn & Suites Sikeston, MO, with an exceptional 9.4 rating, offers free buffet breakfast, free WiFi, and complimentary toiletries. Guests frequently praise the comfortable and clean rooms, as well as the excellent and friendly staff. Its location is often described as superb and convenient. > > > Hampton Inn Sikeston, rated 9.0, provides a great start to the day with free continental breakfast and free WiFi. Guests consistently highlight the nice and clean rooms and the great staff. It is also conveniently located just 1.0 mile from Central Park. > > > Another solid option is the 3-star Best Western Plus Sikeston, which has an 8.4 rating. This hotel includes free full breakfast, free WiFi, and free parking, including RV, bus, and truck parking. Travelers often mention the comfortable and clean rooms, friendly staff, and good value. > > > Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67), with an 8.4 rating, offers a great price point along with free continental breakfast and free WiFi. Guests appreciate the nice and clean rooms, friendly service, and overall value. > > > Lastly, the Holiday Inn Express & Suites Sikeston Southwest by IHG, rated 8.6, features free continental breakfast and free WiFi. It is located just 0.9 miles from Central Park, and guests often comment positively on the good rooms and friendly staff. View all [budget hotels in Sikeston](https://www.expedia.com/Sikeston-Hotels-Cheap-Hotels.0-0-d6058766-tCheapHotels.Travel-Guide-Filter-Hotels) ### What are the most romantic hotels in Sikeston for couples? > This hotel, rated 7.2, offers suites that are described by guests as clean and big, providing ample space for a comfortable stay. Guests also frequently mention the friendly staff and the good complimentary breakfast. Additional conveniences include free WiFi and free self-parking. See all [romantic hotels in Sikeston](https://www.expedia.com/Sikeston-Hotels-Romantic-Hotel.0-0-d6058766-tRomanticHotel.Travel-Guide-Filter-Hotels) ### What are the best hotels in Sikeston near Central Park? > The Hampton Inn Sikeston, with a 9.0 rating, is located just 1.0 mile from Central Park. Guests consistently praise the great breakfast, nice and clean rooms, and the great staff. The hotel also features a pool and offers free continental breakfast, free self-parking, and free WiFi. > > > Another excellent choice is the Holiday Inn Express & Suites Sikeston Southwest by IHG, rated 8.6, and situated 0.9 miles from Central Park. This hotel is known for its great breakfast, good rooms, and friendly staff. It also provides connecting rooms, free cribs, free continental breakfast, free toiletries, free WiFi, and free self-parking. > > > The Fairfield Inn & Suites by Marriott Sikeston, with a 9.2 rating, is 1.2 miles from Central Park. This hotel offers a pool, sofa beds, travel cribs, and free buffet breakfast. > > > The 3-star TownePlace Suites by Marriott Sikeston, rated 9.0, is also 1.2 miles from Central Park. It provides travel cribs, connecting rooms, sofa beds, and free self-serve breakfast. ### When is the best time to go to Sikeston? > During these periods, temperatures are mild, typically ranging from the 60s to high 70s Fahrenheit, making it ideal for exploring local attractions without the intense heat and humidity of summer or the chill of winter. This is also when many local events and festivals are scheduled, offering visitors a chance to experience the community's culture. > > > Couples looking for a relaxing getaway will appreciate the comfortable weather for strolls through the historic downtown area or visiting local vineyards. The moderate temperatures create an inclusive setting for dining outdoors or enjoying a peaceful afternoon. > > > Families traveling with children will find these seasons particularly suitable for visiting parks or attending outdoor events. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Sikeston hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Sikeston hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Sikeston Depot Museum ](https://www.expedia.com/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels) - [Hotels near Central Park ](https://www.expedia.com/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels) - [Hotels near Sikeston Memorial Municipal ](https://www.expedia.com/Sikeston-Memorial-Municipal-Airport-Hotels.0-aSIK-0.Travel-Guide-Filter-Hotels) - [Miner Hotels ](https://www.expedia.com/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [Hotels near The Book Bug ](https://www.expedia.com/The-Book-Bug-Hotels.0-l553248621532655751-0.Travel-Guide-Filter-Hotels) - [Bertrand Hotels ](https://www.expedia.com/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Matthews Hotels ](https://www.expedia.com/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - 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