A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

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Our top choices for St. Charles 4-star hotels

1. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,400 reviews)
"Great location and great place to visit"
United States
Tracy
$113 nightly
The price is $133
Nov 27 - Nov 28
Total with taxes and fees
Hyatt Regency St. Louis at The Arch

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,148 reviews)
"Wonderful Stay!"
United States
A.R.
$147 nightly
The price is $172
Nov 15 - Nov 16
Total with taxes and fees
21C Museum Hotel St Louis

3. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,200 reviews)
"Great Hotel."
United States
Joy
$111 nightly
The price is $130
Nov 27 - Nov 28
Total with taxes and fees
Renaissance St. Louis Airport Hotel

4. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,056 reviews)
"Cool hotel!"
United States
Rebecca
$149 nightly
The price is $177
Nov 18 - Nov 19
Total with taxes and fees
Moonrise Hotel

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,364 reviews)
"Great place to stay."
United States
brandon
$139 nightly
The price is $165
Nov 15 - Nov 16
Total with taxes and fees
Live by Loews - St.Louis

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,094 reviews)
"Very nice hotel, lots of amenities, and restaurants"
United States
Carter
$193 nightly
The price is $226
Nov 16 - Nov 17
Total with taxes and fees
Ameristar Casino Resort and Spa

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,007 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
$174 nightly
The price is $205
Nov 22 - Nov 23
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis

8. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (802 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
$152 nightly
The price is $179
Nov 29 - Nov 30
Total with taxes and fees
Le Méridien St. Louis Clayton

9. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,004 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
$122 nightly
The price is $143
Nov 15 - Nov 16
Total with taxes and fees
The Westin St. Louis

10. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,004 reviews)
"Was a great stay"
United States
Loney
$132 nightly
The price is $159
Nov 20 - Nov 21
Total with taxes and fees
Marriott St. Louis Airport

11. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,841 reviews)
"Great accommodations - highly recommend"
United States
jodi
$87 nightly
The price is $102
Dec 9 - Dec 10
Total with taxes and fees
River City Casino & Hotel

12. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (1,006 reviews)
"This was the best hotel we've ever stayed at in St. Louis. It was walking distance from the dome with convenient parking."
United States
Laura
$127 nightly
The price is $151
Nov 22 - Nov 23
Total with taxes and fees
Marriott St. Louis Grand

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,409 reviews)
"Gorgeous historic hotel close to all main downtown sightseeings."
United States
Anastasia
$95 nightly
The price is $113
Nov 23 - Nov 24
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

14. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,011 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
$128 nightly
The price is $152
Nov 22 - Nov 23
Total with taxes and fees
Drury Plaza Hotel St. Louis Brentwood

15. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,005 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
$149 nightly
The price is $177
Nov 29 - Nov 30
Total with taxes and fees
The Cheshire

16. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,370 reviews)
"Loved our stay!"
United States
Megan
$105 nightly
The price is $125
Dec 10 - Dec 11
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,173 reviews)
"Loved the hotel!"
United States
Stephanie
$103 nightly
The price is $122
Nov 22 - Nov 23
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

18. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,289 reviews)
"AMAZING STAY! AMAZING VIEWS FEOM ROOFTOP BAR!"
United States
Kella
$139 nightly
The price is $165
Nov 22 - Nov 23
Total with taxes and fees
Hilton St. Louis at the Ballpark

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,003 reviews)
"Front desk staff was very helpful in answering question about the property and surrounding area!"
United States
William
$155 nightly
The price is $184
Nov 22 - Nov 23
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton

20. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,162 reviews)
"I enjoyed my stay and parking was safe."
United States
Jacqueline
$110 nightly
The price is $128
Nov 15 - Nov 16
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch
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Explore similar 5-star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

A bridge over a calm river with a sunset sky.

Top St. Charles Hotel Reviews

Find out more about St. Charles

The get-go of any well-deserved trip gets started with selecting a splendid destination. St. Charles has become a popular destination with guests because of everything it offers. However, "location, location, location" applies to more than just your destination. When you want a trip that is amazing from start to finish, you need the ideal hotel.

Accommodations as Gorgeous as the City

St. Charles saw its fair share of visitors this past year. Expedia's review section contains comments to help you decide which hotel is the perfect fit for your vacation. When you reserve a 4-star room you can breathe easy knowing that these properties aim to meet your every need. You'll never have to search long for a tasty breakfast, to sustain your workout routine, or a refreshing spa treatment during your stay, thanks to all these hotels offer. They aim to make the grounds and facilities welcoming from the minute you step onto the property and with every step across their floors. St. Charles has several wonderful hotels that create the absolute perfect vacation.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like in-room coffee or tea, designer bathroom products, and, premium bedding. So, sit back and unwind. Moreover, if you find yourself in need of something more, you can trust the staff will work their best to ensure you continue to be satisfied during your stay. These hotels are so nice that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in St. Charles Today!

Your getaway to St. Charles should be a break from your daily routine. Make sure to book soon. With so few hotels, and a lot of people wanting to vacation in St. Charles, you may miss the chance to snag the perfect place.

Frequently asked questions

What are the best 4-star hotels in St. Charles?
If you're seeking high-quality comfort and lots of amenities during your St. Charles retreat, check in to Ameristar Casino Resort and Spa. This sought-after 4-star hotel comes with premium bedding and concierge services. DoubleTree by Hilton St. Louis - Westport also gets stellar reviews from Expedia guests. Concierge services and a swimming pool are among its conveniences.
How much does it cost to stay in a 4-star hotel in St. Charles?
To find a 4-star hotel in St. Charles that fits your budget, take advantage of Expedia's search and sort filters. Take a look at the availability during your chosen dates and use our pricing filter to set your limit. You can also sort your results by the most affordable option first.

  • Search for the lowest price from $438

What's the difference between 5-star and 4-star hotels in St. Charles?
If you choose to stay at a 4-star hotel in St. Charles, you'll usually find plenty of amenities to make sure you're relaxed, such as a gym, pool and restaurant. You can look forward to top-quality service and deluxe accommodations. Choose a 5-star hotel and you'll get a few more perks — think around-the-clock concierge, on-site spas and opulent turndown services. You're likely to get extra amenities and first-rate services at a 5-star retreat, though both are superb options for luxury guests.

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