Tenderloin, CA

San Francisco

A grand building with a dome and columns, surrounded by well-maintained hedges and a clear blue sky.
A statue of a seated man with a book, surrounded by trees and a classical building with columns.
A classical building with ornate gold detailing, a street lamp, and an American flag.
A large neoclassical building with a prominent dome and columns, featuring ornate gold detailing and a statue on top.
A statue of a woman holding a staff and shield, with an American flag on a building in the background.

Stay near popular Tenderloin attractions

Great American Music Hall

8.0/10 (1 review)
After visiting Great American Music Hall, make a plan to see the other sights and activities in San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.
See properties

Things to do

Official Alcatraz Island Prison Tour with Free App Audio Packages

Alcatraz Inside Prison Tour with Free App Audio Packages

$86
per adult
94% of travellers recommend
Alcatraz Inside Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

$58
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
Aquarium of the Bay General Admission Ticket

San Francisco, Aquarium of the Bay General Admission Ticket

$29
per adult
100% of travellers recommend
San Francisco, Aquarium of the Bay General Admission Ticket
de Young Museum General Admission Ticket

de Young Museum General Admission Ticket

$25
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
San Francisco SkyStar Wheel - Private Gondolas

San Francisco SkyStar Wheel - Private Gondolas

$19
per adult
82% of travellers recommend
San Francisco SkyStar Wheel - Private Gondolas
See all activities in San Francisco

Tenderloin Hotel Deals

The Phoenix Hotel

The Phoenix Hotel

3 out of 5
601 Eddy St San Francisco CA
$107 nightly
The price is $126 total per night from Sep 10 to Sep 11
$126 total
Sep 10 - Sep 11
Total with taxes and fees
Stay at this hotel in San Francisco. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (1,009 reviews)
"I would stay there again. Fun, funky, but updated hotel. Safe parking, helpful staff, good snacks in the lobby to purchase. Rooms are modest,but have everything you need."

Reviewed on Sep 7, 2026

The Phoenix Hotel
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
$152 nightly
The price is $179 total per night from Sep 20 to Sep 21
$179 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
$201 nightly
The price is $236 total per night from Sep 8 to Sep 9
$236 total
Sep 8 - Sep 9
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,676 reviews)
"Very clean and comfortable rooms. Request to move to the top floor was honored after the first night due to noisy upstairs guests. Gym leaves a lot to be desired. Better than average breakfast."

Reviewed on Sep 7, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
$171 nightly
The price is $202 total per night from Oct 2 to Oct 3
$202 total
Oct 2 - Oct 3
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
Hilton San Francisco Union Square
Club Quarters Hotel Embarcadero, San Francisco

Club Quarters Hotel Embarcadero, San Francisco

4 out of 5
424 Clay St San Francisco CA
$133 nightly
The price is $157 total per night from Sep 20 to Sep 21
$157 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Club Quarters Hotel Embarcadero, San Francisco
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
$122 nightly
The price is $144 total per night from Sep 20 to Sep 21
$144 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (3,180 reviews)
"Dusty, not acceptable quality for that price."

Reviewed on Sep 7, 2026

Hilton San Francisco Financial District
See all 4,298 properties in Tenderloin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Tenderloin

Find the best Tenderloin areas and neighborhoods for the activities you enjoy most. Learn more about Tenderloin
Learn more about Tenderloin
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Oracle Park and San Francisco Bay are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like SF Masonic Auditorium and Cable Car Museum.

Tenderloin, CA

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