Tenderloin, CA

San Francisco

A grand building with a dome and columns, surrounded by well-maintained hedges and a clear blue sky.
A statue of a seated man with a book, surrounded by trees and a classical building with columns.
A classical building with ornate gold detailing, a street lamp, and an American flag.
A large neoclassical building with a prominent dome and columns, featuring ornate gold detailing and a statue on top.
A statue of a woman holding a staff and shield, with an American flag on a building in the background.

Stay near popular Tenderloin attractions

Golden Gate Theatre

9.2/10 (7 reviews)
You can enjoy a show at Golden Gate Theatre during your trip to San Francisco. Experience the acclaimed art scene and fascinating museums in this vibrant area.
See properties

Things to do

Alcatraz Inside tour with Round trip ferry & Audio App Packages

Alcatraz Inside tour with Round trip ferry & Audio App Packages

$71
per adult
94% of travellers recommend
Alcatraz Inside tour with Round trip ferry & Audio App Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

$58
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
Aquarium of the Bay General Admission Ticket

San Francisco, Aquarium of the Bay General Admission Ticket

$29
per adult
100% of travellers recommend
San Francisco, Aquarium of the Bay General Admission Ticket
de Young Museum General Admission Ticket

de Young Museum General Admission Ticket

$25
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
San Francisco SkyStar Wheel - Private Gondolas

San Francisco SkyStar Wheel - Private Gondolas

$19
per adult
82% of travellers recommend
San Francisco SkyStar Wheel - Private Gondolas
See all activities in San Francisco

Tenderloin Hotel Deals

The Phoenix Hotel

The Phoenix Hotel

3 out of 5
601 Eddy St San Francisco CA
$139 nightly
The price is $163 total per night from Nov 3 to Nov 4
$163 total
Nov 3 - Nov 4
Total with taxes and fees
Stay at this hotel in San Francisco. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the helpful staff in our ...
The Phoenix Hotel
Embassy Hotel

Embassy Hotel

2.5 out of 5
610 Polk St San Francisco CA
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $83 total per night from Oct 8 to Oct 9
$83 total
Oct 8 - Oct 9
Total with taxes and fees
Stay at this hotel in San Francisco. Enjoy valet parking (surcharge), a 24-hour front desk, and daily housekeeping. Popular attractions Oracle Park and Pier ...
6.4/10 (1,020 reviews)
"The worst hotel"

Reviewed on Oct 4, 2026

Embassy Hotel
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
$152 nightly
The price is $179 total per night from Oct 25 to Oct 26
$179 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (6,374 reviews)
"I loved everything about this hotel. Not one bad thing to say. Staff, housekeeping, restaurants, gym, were all great. Will definitely go back. Only thing bad was the nightly sirens outside but that has nothing to do with the hotel."

Reviewed on Oct 4, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
$157 nightly
The price is $185 total per night from Nov 3 to Nov 4
$185 total
Nov 3 - Nov 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,694 reviews)
"Friendly staff and great location. The breakfast buffet was very good, nice variety of food."

Reviewed on Oct 4, 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
$140 nightly
The price is $165 total per night from Nov 1 to Nov 2
$165 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (3,608 reviews)
"Parking was great and attendants were super helpful and courteous"

Reviewed on Oct 4, 2026

Handlery Union Square Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
$142 nightly
The price is $167 total per night from Nov 1 to Nov 2
$167 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
See all 4,212 properties in Tenderloin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Tenderloin

Find the best Tenderloin areas and neighborhoods for the activities you enjoy most. Learn more about Tenderloin
Learn more about Tenderloin
A pier with a large number of sea lions resting on floating platforms.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A city street with tall buildings, flags, and cars.

South of Market

Oracle Park and Chase Center are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

A cityscape with a prominent skyscraper, a bridge, and a mix of modern and historic buildings.

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like SF Masonic Auditorium and Cable Car Museum.

Tenderloin, CA

Choose one or more items to build your trip:

Explore a world of travel with Expedia