Find 2 Star Hotels in East Prairie, MO from $60

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Our top choices for East Prairie 2-star hotels

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
7.2 out of 10, Good, (1002)
"A great stay in every aspect. "
United States
Gertrude
$63 nightly
The price is $72
Dec 14 - Dec 15
Total with taxes and fees
Days Inn and Suites by Wyndham Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (440)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
$95 nightly
The price is $108
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Sikeston

Sleep Inn at Discovery Park of America

2.5 star property
Union City
9.2 out of 10, Wonderful, (315)
"Wonderful breakfast, awesome room"
United States
Kimberly
$81 nightly
The price is $96
Dec 30 - Dec 31
Total with taxes and fees
Sleep Inn at Discovery Park of America

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very Good, (716)
"Stayed one night. Good rate for the Hotel "
United States
Paul
$55 nightly
The price is $63
Dec 10 - Dec 11
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very Good, (1003)
"Easy parking , quiet and comfortable bed , we’ll stop again on our way back "
United States
joseph
$71 nightly
The price is $81
Dec 14 - Dec 15
Total with taxes and fees
Best Western Plus Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1002)
"Everything was clean, staff was friendly "
United States
Matthew
$75 nightly
The price is $86
Dec 14 - Dec 15
Total with taxes and fees
Pear Tree Inn Sikeston

Hospitality House Union City I 69 / US 51

2.5 star property
Union City
6.8 out of 10, (366)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
$54 nightly
The price is $65
Jan 8 - Jan 9, 2026
Total with taxes and fees
Hospitality House Union City I 69 / US 51

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (40)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
$101 nightly
The price is $114
Dec 18 - Dec 19
Total with taxes and fees
Fairfield Inn & Suites by Marriott Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
$93 nightly
The price is $105
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (612)
"Staff was great! Room was nice. "
United States
Lana
$62 nightly
The price is $69
Jan 7 - Jan 8, 2026
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO

Holiday Inn Express & Suites Union City by IHG

2.5 star property
Union City
9.4 out of 10, Exceptional, (309)
"Rooms were spotless and comfortable. The bathroom had all the amenities. Great view. Awesome buffet breakfast to wake up to. "
United States
Rickey Smith
$102 nightly
The price is $121
Dec 19 - Dec 20
Total with taxes and fees
Holiday Inn Express & Suites Union City by IHG

Hampton Inn Union City

2.5 star property
Union City
9.6 out of 10, Exceptional, (164)
"Clean room, nice breakfast"
United States
STUART
$87 nightly
The price is $104
Dec 26 - Dec 27
Total with taxes and fees
Hampton Inn Union City

Quality Inn Union City US 51

2.5 star property
Union City
8.4 out of 10, Very Good, (484)
"The Staff for sure is what keeps me coming back! Plus the rooms are very clean!"
United States
Walter
$67 nightly
The price is $80
Dec 28 - Dec 29
Total with taxes and fees
Quality Inn Union City US 51

New Orleans Inn Portageville

2.5 star property
Portageville
8.0 out of 10, Very Good, (725)
"Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling."
United States
Roger
$55 nightly
The price is $60
Dec 21 - Dec 22
Total with taxes and fees
New Orleans Inn Portageville

Quality Inn Charleston - Sikeston

2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
$65 nightly
The price is $72
Dec 27 - Dec 28
Total with taxes and fees
Quality Inn Charleston - Sikeston

Super 8 By Wyndham Marston

2.0 star property
Marston
7.8 out of 10, Good, (38)
"Comfortable bed. Quiet. "
Canada
Ronald
$58 nightly
The price is $66
Dec 11 - Dec 12
Total with taxes and fees
Super 8 By Wyndham Marston

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
Sikeston
6.6 out of 10, (561)
"ALL GREAT"
United States
NELSON
$59 nightly
The price is $68
Dec 11 - Dec 12
Total with taxes and fees
Super 8 by Wyndham Sikeston/Miner Area

Reelfoot Lake Inn

2.0 star property
Tiptonville
7.2 out of 10, Good, (459)
"Nice and quiet but there were bugs in the room the fridge didn't keep things cold and the A/C didn't keep the room cool. Great place if you're a fisherman."
United States
Carla
$70 nightly
The price is $80
Dec 10 - Dec 11
Total with taxes and fees
Reelfoot Lake Inn

Comfort Inn & Suites Sikeston I-55

2.5 star property
Sikeston
8.4 out of 10, Very Good, (281)
"Room was clean, breakfast was very good. "
United States
Connie
$84 nightly
The price is $96
Dec 14 - Dec 15
Total with taxes and fees
Comfort Inn & Suites Sikeston I-55

Country Hearth Inn & Suites Union City

2.5 star property
Union City
8.6 out of 10, Excellent, (547)
"Clean rooms, helpful and polite staff"
United States
Jennifer
$72 nightly
The price is $85
Dec 10 - Dec 11
Total with taxes and fees
Country Hearth Inn & Suites Union City
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Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

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East Prairie Motel Guide

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These smaller places are ideal if you need a home base that lets you easily explore the local sights; many of the best motels in East Prairie are located near major freeways and public transportation. Plus, when you book a cheap deal on a motel in East Prairie, you’ll find quiet rooms, complimentary toiletries, and comfortable sleeping areas, so you can unwind after a long day.

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