Find 5 Star Hotels in Fort Myers River District, FL from $127
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Check availability on Fort Myers River District 5 Star Hotels
Compare Fort Myers River District 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Gullwing by VTrips
Sundial Beach Resort & Spa
Latitude Adjustment
Palm Haven!
Villa Alaia
Bliss on Eternity by Vtrips
Sunshine Escape
Sapphire Villa
Deja Blue Villa
Whispering Palms Villa
Whiskey Village 103
Explore similar 4-star hotels
Marriott Sanibel Harbour Resort & Spa
There's nothing wrong with enjoying the finer things in life. Add even more luxury on your next trip to Fort Myers River District by treating yourself to the best of the best when it comes to accommodation. It's an ideal combination. There's no reason to delay a getaway to Fort Myers River District any longer. You'll join the multitudes of vacationers who have made Fort Myers River District so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Our 5-star hotels in Fort Myers River District are the perfect places to relax in during your next chunk of time off.
Get a Great Deal on 5-Star Hotels in Fort Myers River District
You'll have a wonderful time at one of these 5-star hotels. Excellent customer care, luxurious bedding, and fabulous spa offerings are all on offer. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A Swedish massage to help your cares fall away? A concierge to help you pick out your next adventure? Plush carpeting, lip-smacking main courses, and even space for your family pet in some cases...these hotels are one-of-a-kind.
You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Fort Myers River District are the perfect place to rest up after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.
Your Getaway Starts Today
The results are in, and Fort Myers River District 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Decide on one of Expedia's Fort Myers River District 5-star hotels today and settle down in luxe surroundings when you're ready.
Frequently asked questions
Fort Myers River District Hotels by Star Rating
Hotels in Fort Myers River District Neighborhoods
Stay near popular Fort Myers River District attractions
- Centennial Park
- Sidney & Berne Davis Art Center
- Florida Repertory Theater
- Fort Myers Historical Museum
- Harborside Event Center
- Butterfly Estates
- Key West Express
- Hertz Arena
- Florida Gulf Coast University
- JetBlue Park at Fenway South
- Sanibel Island Southern Beach
- Coconut Point Mall
- Babcock Ranch Preserve
- Gulf Coast Town Center
- Lynn Hall Memorial Park
- Edison Mall
- Lee Health Sports Complex
- Bell Tower Shops
- Estero Boulevard Beach
- Edison and Ford Winter Estates
More Hotel Options in Fort Myers River District
- Beach Hotels (2)
- Boutique Hotels (1)
- Business Hotels (2)
- Family Hotels (2)
- Golf Hotels (3)
- Historic Hotels (3)
- Hotel Wedding Venues (2)
- Hotel with a Concierge (2)
- Hotels & Resorts for Couples (2)
- Hotels on the River (1)
- Hotels with Air Conditioning (3)
- Hotels with Balconies (1)
- Hotels with Bars (2)
- Hotels with Connecting Rooms (1)
- Hotels with Free Breakfast (2)
- Hotels with Free Parking (2)
- Hotels with Free Wifi (3)
- Hotels with Laundry Facilities (2)
- Hotels with Restaurants (3)
- Hotels with Suites (1)
- Hotels with a Gym (2)
- Hotels with a Pool (2)
- Hotels with a View (2)
- Hotels with an Outdoor Pool (2)
- Luxury Hotels (2)
- Non-Smoking Hotels (2)
- Oceanfront Hotels (1)
- Pet-friendly Hotels (1)
- Romantic Hotels (1)
Explore more hotels
- Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
- Best Western Fort Myers Inn & Suites
- Homewood Suites by Hilton - Fort Myers
- Comfort Inn & Suites Airport
- Americas Best Value Inn Ft. Myers
- Hyatt Place Fort Myers/at The Forum
- Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
- DiamondHead Beach Resort
- Quality Inn & Suites Lehigh Acres Fort Myers
- Baymont by Wyndham Fort Myers Central
- Holiday Inn Fort Myers - Downtown Area, an IHG Hotel
- La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
- Allure Suites
- The Westin Cape Coral Resort At Marina Village
- Hilton Garden Inn Ft Myers
- Hilton Garden Inn Fort Myers Airport/FGCU
- Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
- Holiday Inn Express Cape Coral-Fort Myers Area, an IHG Hotel
- Embassy Suites by Hilton Fort Myers Estero
- Candlewood Suites Fort Myers Sanibel Gateway, an IHG Hotel