Depew Vacation Rentals

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Our top choices for Depew vacation rentals

Tiny Spa Cottage Retreat

Tiny Spa Cottage Retreat
Alden
9.8 out of 10, Exceptional, (120 reviews)
"Everything about this tiny cottage was perfect. I was looking for a quiet relaxing long weekend away from work & couldnt have asked for more."
United States
MELODY K.
$182 nightly
The price is $203
Jun 11 - Jun 12
Total with taxes and fees
Tiny Spa Cottage Retreat

ADA Studio 6 Buffalo|Queen Bed|RI Shower|Nsmk Kitchen

ADA Studio 6 Buffalo|Queen Bed|RI Shower|Nsmk Kitchen
Buffalo NY
10.0 out of 10, Exceptional, (42 reviews)
"Great hotel clean and kitchen"
United States
Anonymous traveler
$87 nightly
The price is $99
Jul 1 - Jul 2
Total with taxes and fees
ADA Studio 6 Buffalo|Queen Bed|RI Shower|Nsmk Kitchen

Cozy Cuddler's Cottage

Cozy Cuddler's Cottage
West Falls
9.8 out of 10, Exceptional, (9 reviews)
"Awesome location. Friendly staff. Great value and close to family!!"
United States
Bill
$226 nightly
The price is $253
Jun 8 - Jun 9
Total with taxes and fees
Cozy Cuddler's Cottage

Spacious kid friendly apt near East Aurora

Spacious kid friendly apt near East Aurora
West Falls
10.0 out of 10, Exceptional, (10 reviews)
"Great stay in a great location. "
United States
Anonymous traveler
$257 nightly
The price is $287
Jun 9 - Jun 10
Total with taxes and fees
Spacious kid friendly apt near East Aurora

Luxury Villa

Luxury Villa
Lancaster
9.8 out of 10, Exceptional, (16 reviews)
"Really enjoyed my stay! They made us very comfortable and let us check in early due to our early flight 10/10 come check it out "
United States
Da’Lisha P.
$168 nightly
The price is $188
Jun 9 - Jun 10
Total with taxes and fees
Luxury Villa

Cozy 3-bedroom house in charming Buffalo with WiFi, AC

Cozy 3-bedroom house in charming Buffalo with WiFi, AC
Kaisertown
8.4 out of 10, Very Good, (15 reviews)
"Enjoyed the stay! "
United States
Jamie M.
$169 nightly
The price is $193
Jun 8 - Jun 9
Total with taxes and fees
Cozy 3-bedroom house in charming Buffalo with WiFi, AC

Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen

Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen
Buffalo NY
10.0 out of 10, Exceptional, (48 reviews)
"good place to stay"
United States
Anonymous traveler
$92 nightly
The price is $105
Jul 1 - Jul 2
Total with taxes and fees
Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen

Suite Retreat: quiet comfort on walkable village lane

Suite Retreat: quiet comfort on walkable village lane
Akron
10.0 out of 10, Exceptional, (11 reviews)
"Easy check in process, very clean property with thoughtful touches and amenities that exceed expectations."
United States
Kellerie
$275 nightly
The price is $296
Jun 9 - Jun 10
Total with taxes and fees
Suite Retreat: quiet comfort on walkable village lane

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.
Blasdell
9.8 out of 10, Exceptional, (7 reviews)
"The place was fairly clean. Well stocked and the hosts were incredibly nice! "
United States
Matthew
$260 nightly
The price is $290
Jun 8 - Jun 9
Total with taxes and fees
Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor
Orchard Park
9.8 out of 10, Exceptional, (28 reviews)
"Such a fun spot! "
United States
Jamie F.
$254 nightly
The price is $284
Jun 15 - Jun 16
Total with taxes and fees
Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Regency Retreat

Regency Retreat
3.0 star property
Lockport
$386 nightly
The price is $437
Jun 25 - Jun 26
Total with taxes and fees
Regency Retreat

Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!

Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!
Buffalo
9.8 out of 10, Exceptional, (27 reviews)
"Nice accommodation for the cost with host being responsive with any questions we had along with any requests.We would recommend to anyone and will stay again when in the area."
United States
Aimee R.
$180 nightly
The price is $201
Jun 11 - Jun 12
Total with taxes and fees
Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!

Nice house with private parking, king bed fenced yard

Nice house with private parking, king bed fenced yard
West Seneca
8.8 out of 10, Excellent, (10 reviews)
"Yes suitable for pets. Kitchen had what we needed. We very much enjoyed our stay, immaculate condition. "
United States
Sean
$313 nightly
The price is $372
Jun 15 - Jun 16
Total with taxes and fees
Nice house with private parking, king bed fenced yard

420 Friendly 3 bedroom upstairs apartment. Street parking only.

420 Friendly 3 bedroom upstairs apartment. Street parking only.
Seneca
9.4 out of 10, Exceptional, (72 reviews)
"Excellent stay! All the things we needed and then some :) highly recommend! Will be staying here anytime I am in the area!"
United States
Kerry G.
$179 nightly
The price is $182
Jul 2 - Jul 3
Total with taxes and fees
420 Friendly 3 bedroom upstairs apartment. Street parking only.

‘Turtle Cove Bay Beach House’ ~ 13 Mi to Buffalo!

‘Turtle Cove Bay Beach House’ ~ 13 Mi to Buffalo!
Lake View
9.8 out of 10, Exceptional, (23 reviews)
"We had a great family stay at the Turtle Cove Beach house. The owner was very proactive on communication and making sure our stay met all our needs."
United States
Jim W.
‘Turtle Cove Bay Beach House’ ~ 13 Mi to Buffalo!

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!
Grand island
9.8 out of 10, Exceptional, (18 reviews)
"Accomodations were great"
United States
Ginny A.
$231 nightly
The price is $258
Jun 11 - Jun 12
Total with taxes and fees
2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!

Delightful dwelling

Delightful dwelling
Elmwood Bidwell
10.0 out of 10, Exceptional, (2 reviews)
"The host is very friendly and accommodating. The unit is very nice, private and quite. The neighborhood is safe with resturants and shops within 15 minutes walk. Highly recommend this unit."
United States
Nasser K.
$274 nightly
The price is $314
Jun 14 - Jun 15
Total with taxes and fees
Delightful dwelling

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo
Lancaster
10.0 out of 10, Exceptional, (30 reviews)
"It was great stay"
United States
Vomshankar R.
$386 nightly
The price is $428
Jun 16 - Jun 17
Total with taxes and fees
Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo

Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo

Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo
3.0 star property
Lancaster
$382 nightly
The price is $427
Jun 16 - Jun 17
Total with taxes and fees
Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo

4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!

4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!
Grand island
10.0 out of 10, Exceptional, (9 reviews)
"Nice welcoming amenities, is walking distance to a restaurant, and only a few minute drive to Casino and Niagara Falls. "
United States
Denise P.
$170 nightly
The price is $190
Jun 8 - Jun 9
Total with taxes and fees
4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Depew Hotel Reviews

Find out more about Depew

Everything you need to know about Depew vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Depew vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Depew vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Depew vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Depew. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Depew in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $99 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Depew rentals

At Expedia, we put the best Depew vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Depew rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Depew vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Depew. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Depew?

Yes, we have vacation rentals near well known sights in Depew, or you can choose a secluded option if you're looking for relaxation. Depew is known for its shopping and restaurants. Make sure you have time to check out the sporting events and waterfalls during your trip.

What are some of the best vacation home rentals in Depew?

HTR Niagara: Visitors like this Depew vacation home rental. It is on the riverwalk and equipped with air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities like a coffee maker and free parking are also available for your convenience.

How many vacation rentals will I find in Depew?

Choose from 6 Expedia vacation rentals in Depew for a memorable vacation.

What can I see and do in Depew?

While exploring the area, visit family-friendly sights like Six Flags Darien Lake, or get outside and enjoy nature at Glen Falls. Highmark Stadium and Walden Galleria Mall are a couple of places you'll find in the larger area.

What are vacation rentals like in Depew?

Vacation rentals are private accommodations you can reserve for several days or more in Depew. Vacation rentals feature extras like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a family trip.