This culture and arts hub in Key West Historic District comes recommended by travelers, so be sure to put it on your to-do list. Don't stop there, though. There are a lot more spots ready for you to check out after San Carlos Institute - Casa Cuba. Ernest Hemingway Home and Museum, Audubon House and Tropical Gardens, and Mallory Square are not far away.

Plan a trip to see San Carlos Institute - Casa Cuba

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Hyatt Vacation Club at Beach House, Key West

Save 100% on your flight

$871

per person

Jan 5 - Jan 10

found 1 day ago

Roundtrip flight included

Boston (BOS) to Key West (EYW)

18.8/10 Exceptional! (1,002 reviews)

People above us were ridiculously loud both nights till midnight and 1:00am

Reviewed on Nov 22, 2025

Oceans Edge Key West Resort, Hotel & Marina

Save 100% on your flight

$1,942

per person

Dec 29 - Jan 2

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Key West (EYW)

18/10 Exceptional! (1,736 reviews)

Everything was great!

Reviewed on Nov 20, 2025

The Key West Hotel

Key West Historic District

$1,601

per person

Jan 26 - Jan 30

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Key West (EYW)

18.4/10 Exceptional! (505 reviews)

Great room. Great tiki bar. Great tunes. Great staff.

Reviewed on Nov 21, 2025

Browse tours and tickets to explore San Carlos Institute - Casa Cuba

Tours & day trips

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Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar

History & culture

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Key West Conch Tour Train

Free cancellation available

Wildlife & nature

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Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

Free cancellation available

Private & custom tours

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Dry Tortugas National Park Day Trip by Luxury Private Boat

Free cancellation available

Adventure & outdoor

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Key West Half-Day Fishing Charter

Free cancellation available

Popular places to visit

Jackson Square

4.5/5(81 reviews)

You can learn about the history of Key West with a stop at Jackson Square. Stroll along the beautiful beaches or discover the area's beautiful sunsets.

Duval Street

4.5/5(3,475 reviews)

Along one of the southernmost streets in the continental U.S., enjoy a lively area filled with shops, pubs, restaurants and lots of sidewalk acts and vendors.

Oldest House Museum and Garden

4.5/5(8 reviews)

With its period décor and vintage documents, South Florida’s oldest house provides an impression of life in the Florida Keys archipelago in the 19th century

22 room mansion all decked out for Valentine’s Day. Home to Florida’s 1st millionaire.

Curry Mansion Museum

You can spend time studying the exhibits at Curry Mansion Museum during your trip to Key West. Stroll along the area's seaside or experience its lively festivals.