Tenderloin, CA

San Francisco

A grand building with a dome and columns, surrounded by well-maintained hedges and a clear blue sky.
A statue of a seated man with a book, surrounded by trees and a classical building with columns.
A classical building with ornate gold detailing, a street lamp, and an American flag.
A large neoclassical building with a prominent dome and columns, featuring ornate gold detailing and a statue on top.
A statue of a woman holding a staff and shield, with an American flag on a building in the background.

Stay near popular Tenderloin attractions

Great American Music Hall

8.0/10 (1 review)
After visiting Great American Music Hall, make a plan to see the other sights and activities in San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.
See properties

Things to do

Aquarium of the Bay General Admission Ticket

San Francisco, Aquarium of the Bay General Admission Ticket

$29
per adult
100% of travellers recommend
San Francisco, Aquarium of the Bay General Admission Ticket
Golden Gate Bridge at night

San Francisco Night Tour

$48
per adult
78% of travellers recommend
San Francisco Night Tour
Bridge 2 Bridge Tour: Golden Gate Bridge to Bay Bridge

San Francisco Bridge to Bridge Cruise (90-minutes)

$48
per adult
94% of travellers recommend
San Francisco Bridge to Bridge Cruise (90-minutes)
See all activities in San Francisco

Tenderloin Hotel Deals

The Phoenix Hotel

The Phoenix Hotel

3 out of 5
601 Eddy St San Francisco CA
$133 nightly
The price is $157 total per night from Oct 8 to Oct 9
$157 total
Oct 8 - Oct 9
Total with taxes and fees
Stay at this hotel in San Francisco. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (1,008 reviews)
"As Good as It gets for the area and price. Nice pool. Convenient parking. There is a lot of homeless in the area but they don't seem to be bad people. just minding their own business. I was never asked for any money walking down the streets."

Reviewed on Sep 13, 2026

The Phoenix Hotel
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
$201 nightly
The price is $237 total per night from Sep 18 to Sep 19
$237 total
Sep 18 - Sep 19
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,687 reviews)
"The hotel was in an amazing location. Rooms were clean and the staff was very helpful and friendly. We could walk to most all attractions. The breakfast was spectacular. I loved the fire tables with the seating. We were disappointed there was no hot tub and we could hear the upstairs people walking ..."

Reviewed on Sep 13, 2026

Hotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
$161 nightly
The price is $189 total per night from Sep 20 to Sep 21
$189 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
$122 nightly
The price is $144 total per night from Sep 20 to Sep 21
$144 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
The Pickwick Hotel

The Pickwick Hotel

3.5 out of 5
85 5th St San Francisco CA
$109 nightly
The price is $128 total per night from Oct 1 to Oct 2
$128 total
Oct 1 - Oct 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff ...
7.8/10 Good! (1,534 reviews)
"Great stay."

Reviewed on Sep 13, 2026

The Pickwick Hotel
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St San Francisco CA
$161 nightly
The price is $189 total per night from Sep 21 to Sep 22
$189 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff ...
9.4/10 Exceptional! (3,451 reviews)
"Somewhat dissapointing"

Reviewed on Sep 12, 2026

Chancellor Hotel on Union Square
See all 4,264 properties in Tenderloin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Tenderloin

Find the best Tenderloin areas and neighborhoods for the activities you enjoy most. Learn more about Tenderloin
Learn more about Tenderloin
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Oracle Park and San Francisco Bay are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like SF Masonic Auditorium and Cable Car Museum.

Tenderloin, CA

Choose one or more items to build your trip:

Explore a world of travel with Expedia