Tenderloin, CA

San Francisco

A grand building with a dome and columns, surrounded by well-maintained hedges and a clear blue sky.
A statue of a seated man with a book, surrounded by trees and a classical building with columns.
A classical building with ornate gold detailing, a street lamp, and an American flag.
A large neoclassical building with a prominent dome and columns, featuring ornate gold detailing and a statue on top.
A statue of a woman holding a staff and shield, with an American flag on a building in the background.

Stay near popular Tenderloin attractions

Great American Music Hall

8.0/10 (1 review)
After visiting Great American Music Hall, make a plan to see the other sights and activities in San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.
See properties

Things to do

Official Alcatraz Island Prison Tour with Free App Audio Packages

Alcatraz Inside Prison Tour with Free App Audio Packages

$86
per adult
98% of travellers recommend
Alcatraz Inside Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$55
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

$58
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
de Young Museum General Admission Ticket

de Young Museum General Admission Ticket

$20
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
San Francisco SkyStar Wheel - Private Gondolas

San Francisco SkyStar Wheel - Private Gondolas

$19
per adult
80% of travellers recommend
San Francisco SkyStar Wheel - Private Gondolas
Golden Gate Bridge at night

San Francisco Night Tour

$53
per adult
78% of travellers recommend
San Francisco Night Tour
See all activities in San Francisco

Tenderloin Hotel Deals

The Phoenix Hotel

The Phoenix Hotel

3 out of 5
601 Eddy St San Francisco CA
$102 nightly
The price is $120 total per night from Aug 23 to Aug 24
$120 total
Aug 23 - Aug 24
Total with taxes and fees
Stay at this hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,017 reviews)
"The pool is great. From 3ft to 8ft. There are many restaurants nearby."

Reviewed on Aug 6, 2026

The Phoenix Hotel
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
$152 nightly
The price is $179 total per night from Aug 31 to Sep 1
$179 total
Aug 31 - Sep 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (6,129 reviews)
"Got to stay in the City for a few days and it was the best trip! Long overdue time in this area. So many great restaurants close by and traveling by Cable Car never disappoints. The Hotel staff were all charming and helpful. Thanks for the great hospitality and memories. See you again!"

Reviewed on Aug 7, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
$163 nightly
The price is $192 total per night from Aug 31 to Sep 1
$192 total
Aug 31 - Sep 1
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,602 reviews)
"this place is exactly what you looking for."

Reviewed on Aug 7, 2026

Hotel Riu Plaza Fisherman's Wharf
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
$144 nightly
The price is $169 total per night from Aug 13 to Aug 14
$169 total
Aug 13 - Aug 14
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (3,401 reviews)
"Nice Stay! Good Location!"

Reviewed on Aug 7, 2026

Club Quarters Hotel in San Francisco
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $187 total per night from Sep 4 to Sep 5
$187 total
Sep 4 - Sep 5
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (3,402 reviews)
"Great location, near Union Square. Many options for food and shopping. Easy to walk around in the area. Good transportation options."

Reviewed on Aug 7, 2026

Handlery Union Square Hotel
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St San Francisco CA
$141 nightly
The price is $166 total per night from Sep 5 to Sep 6
$166 total
Sep 5 - Sep 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
8.8/10 Excellent! (1,576 reviews)
"Clean room and nice staff, bottom floor water station didn’t work for duration of my stay so I had to use the one in the gym"

Reviewed on Aug 7, 2026

Parc 55 San Francisco - A Hilton Hotel
See all 4,304 properties in Tenderloin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Tenderloin

Find the best Tenderloin areas and neighborhoods for the activities you enjoy most. Learn more about Tenderloin
Learn more about Tenderloin
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Oracle Park and Chase Center are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like SF Masonic Auditorium and Cable Car Museum.

Tenderloin, CA

Choose one or more items to build your trip:

Explore a world of travel with Expedia