Find Resorts & Hotels with Spas in Santa Fe, TX
- Upfront pricingOur total price for your stay includes taxes and fees
- Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
- Be pickySearch almost a million properties worldwide
Check availability on Santa Fe Resorts & Hotels with Spas
Our top choices for Santa Fe hotels with a spa

Moody Gardens Hotel, Spa and Convention Center
Moody Gardens Hotel, Spa and Convention CenterNear West End
8.8 out of 10, Excellent, (1944)
$86 nightly
The price is $99
Jan 12 - Jan 13, 2026
Total with taxes and fees

8.8 out of 10, Excellent, (1281)
$170 nightly
The price is $196
Dec 25 - Dec 26
Total with taxes and fees

Holiday Inn Resort: Galveston-On The Beach by IHG
Holiday Inn Resort: Galveston-On The Beach by IHGMidtown
8.4 out of 10, Very Good, (1002)
$118 nightly
The price is $136
Dec 30 - Dec 31
Total with taxes and fees

South Shore Harbour Resort & Conference Center
South Shore Harbour Resort & Conference CenterLeague City
9.0 out of 10, Wonderful, (1005)
$129 nightly
The price is $146
Dec 14 - Dec 15
Total with taxes and fees

9.0 out of 10, Wonderful, (1149)
$247 nightly
The price is $285
Dec 14 - Dec 15
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Santa Fe Hotel Reviews

The San Luis Resort, Spa & Conference Center
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Haak Vineyards and Winery
- Hotels near Chaparral Golf Club
- Hotels near Tanger Outlets
- Hotels near Dickinson Historic Railroad Center
- Hotels near Bay Area Raceway
- Hotels near Outlet Shops at La Marque
- Hotels near Mall of the Mainland
- Hotels near Bayou Wildlife Park
- Hitchcock Hotels
- Hotels near Paul Hopkins Park
- Cabin Rentals in Hitchcock
- Motels in Hitchcock
- Vacation Homes in Hitchcock
- Scottish Inn Hotels in Hitchcock
- B&B in Hitchcock
- 4 Star Hotels in Hitchcock
- 5 Star Hotels in Hitchcock
- Cheap Hotels in Dickinson
- Hotels with Hot Tubs in Dickinson
- Pet-friendly Hotels in Dickinson
- Extended Stay Hotels in Dickinson
- Beach Hotels in Dickinson
- Hotels with a Pool in Dickinson
- Luxury Hotels in Dickinson
- Hotels with Free Breakfast in Dickinson
- Hotels with a View in Dickinson
- Family Hotels in Dickinson
- Hotels with Restaurants in Dickinson
- Resorts & Hotels with Spas in Dickinson
- Hotels near College of the Mainland
- Dickinson Hotels
- Motels in Dickinson
- Cabin Rentals in Dickinson
- B&B in Dickinson
- 4 Star Hotels in Dickinson
- Vacation Homes in Dickinson
- Villas in Dickinson
- Resorts in Dickinson
- Cottages in Dickinson
- Hotels near Beacon Lake Golf Course
- Hillcrest Hotels
- Cheap Hotels in La Marque
- Hotels with Free Breakfast in La Marque
- Hotels with Bars in La Marque
- Beach Hotels in La Marque
- Extended Stay Hotels in La Marque
- Hotels with smoking rooms in La Marque
- Luxury Hotels in La Marque
- Hotels with Hot Tubs in La Marque
- Historic Hotels in La Marque
- Family Hotels in La Marque
- Hotels with Balconies in La Marque
- Hotels with an Outdoor Pool in La Marque
- Hotels with Connecting Rooms in La Marque
- Hotel Wedding Venues Hotels in La Marque
- Hotels with Air Conditioning in La Marque
- La Marque Hotels
- Motel 6 Hotels in La Marque
- Apartments in La Marque
- La Quinta Inn & Suites Hotels in La Marque
- Best Western Hotels in La Marque
- Cabin Rentals in La Marque
- B&B in La Marque
- Motels in La Marque
- Car rentals near Haak Vineyards and Winery
- Car rentals near Algoa
- Car rentals near Dickinson Historic Railroad Center
- Car rentals near Hitchcock
- Car rentals near Dickinson
- Hertz Rental Cars in Dickinson
- Enterprise Rental Cars in Dickinson
- Van Car Rentals in Dickinson
- National Car Rental Rental Cars in Dickinson
- Car rentals near Hillcrest
- Car rentals near La Marque
- Van Car Rentals in La Marque























