Photo by Michael Schuier

Find hotels in Southeast Iowa from $61

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Compare 209 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Casino
The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa

3.5 star property
Burlington
9.2 out of 10, Wonderful, (320)
"Staff was friendly and helpful. Accomodations were excellent."
United States
Phillip
$159 nightly
The price is $178
Dec 14 - Dec 15
Total with taxes and fees
The Catfish Bend Inn & Spa
Terrace/patio
Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

2.5 star property
Fort Madison
9.4 out of 10, Exceptional, (646)
"Always love staying here while visiting family. Very clean and comfortable beds "
United States
Jessica
$75 nightly
The price is $84
Dec 10 - Dec 11
Total with taxes and fees
Cobblestone Inn & Suites - Fort Madison
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG

2.5 star property
Burlington
8.6 out of 10, Excellent, (463)
"Friendly staff and very clean hotel"
United States
Julie
$124 nightly
The price is $139
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Hotel & Suites Burlington by IHG
Lobby
Comfort Suites Burlington

Comfort Suites Burlington

2.5 star property
Burlington
8.8 out of 10, Excellent, (738)
"Great place to stay, very friendly check-in staff. Nice to have food on-site. "
United States
Kiley
$110 nightly
The price is $124
Dec 21 - Dec 22
Total with taxes and fees
Comfort Suites Burlington
Lobby
Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk

2.5 star property
Keokuk
6.2 out of 10, (489)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
United States
Marty
$56 nightly
The price is $63
Jan 4 - Jan 5, 2026
Total with taxes and fees
Baymont by Wyndham Keokuk
Reception
Quality Inn & Suites

Quality Inn & Suites

2.5 star property
Mount Pleasant
7.8 out of 10, Good, (111)
"Very happy with my stay "
United States
timothy
$63 nightly
The price is $70
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn & Suites
Water park
Fun City Resort Hotel

Fun City Resort Hotel

3.5 star property
Burlington
8.4 out of 10, Very Good, (294)
"Room was great! "
United States
Gail
$168 nightly
The price is $188
Dec 10 - Dec 11
Total with taxes and fees
Fun City Resort Hotel
Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

2.5 star property
Keokuk
8.4 out of 10, Very Good, (749)
"Great staff! Clean hotel!"
United States
Matthew
$80 nightly
The price is $90
Dec 21 - Dec 22
Total with taxes and fees
Quality Inn & Suites Keokuk North
Free buffet breakfast
Quality Inn Burlington near Hwy 34

Quality Inn Burlington near Hwy 34

2.5 star property
Burlington
7.4 out of 10, Good, (400)
"well cared for inexpensive property "
United States
Christopher
$70 nightly
The price is $79
Jan 9 - Jan 10, 2026
Total with taxes and fees
Quality Inn Burlington near Hwy 34
Indoor pool
AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington

2.5 star property
West Burlington
7.0 out of 10, Good, (827)
"Hair in the tub and bed not always made up. Great breakfast and early, loved it."
United States
james
$58 nightly
The price is $65
Jan 4 - Jan 5, 2026
Total with taxes and fees
AmericInn by Wyndham West Burlington
Front of property - evening/night
Fairfield Inn & Suites by Marriott Burlington

Fairfield Inn & Suites by Marriott Burlington

2.5 star property
Burlington
8.4 out of 10, Very Good, (295)
"It was quiet & they gave us water, when we checked in, was hot out, so that was so nice!"
United States
Loren
$121 nightly
The price is $136
Jan 9 - Jan 10, 2026
Total with taxes and fees
Fairfield Inn & Suites by Marriott Burlington
Grand Suite | City view
Nauvoo Temple House Hotel

Nauvoo Temple House Hotel

2.0 star property
Nauvoo
9.0 out of 10, Wonderful, (337)
"It was a nice historic place to stay. "
United States
Derik
$87 nightly
The price is $98
Jan 3 - Jan 4, 2026
Total with taxes and fees
Nauvoo Temple House Hotel
Indoor pool, open 7 AM to 10 PM, pool umbrellas
Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61

2.5 star property
Fort Madison
8.6 out of 10, Excellent, (570)
"Quiet, large parking lot, restaurant next door, free breakfast was good, hot tub and pool very nice. "
United States
Audrey
$80 nightly
The price is $89
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn & Suites Fort Madison near Hwy 61
Front of property
Evans Holly Grove Inn B&B

Evans Holly Grove Inn B&B

4.0 star property
Burlington
9.6 out of 10, Exceptional, (195)
"Delicious breakfast!!!"
United States
Geremy
$136 nightly
The price is $153
Dec 15 - Dec 16
Total with taxes and fees
Evans Holly Grove Inn B&B
Indoor pool
The Inn at Old Nauvoo

The Inn at Old Nauvoo

2.0 star property
Nauvoo
8.8 out of 10, Excellent, (370)
"Clean room and friendly staff "
United States
Gena
$113 nightly
The price is $128
Dec 10 - Dec 11
Total with taxes and fees
The Inn at Old Nauvoo
Exterior
Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

2.5 star property
Mount Pleasant
8.2 out of 10, Very Good, (775)
"It was perfect. Friendly staff very clean accommodations. Sonjia Steele "
United States
Sonjia
$72 nightly
The price is $81
Dec 15 - Dec 16
Total with taxes and fees
Best Western Mt. Pleasant Inn
Exterior
Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington

2.5 star property
Burlington
9.6 out of 10, Exceptional, (304)
"Very clean and rooms are huge!"
United States
Chad
$135 nightly
The price is $152
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn & Suites Burlington
Standard Room, 2 Double Beds | Iron/ironing board, free WiFi, bed sheets
Chief Motel

Chief Motel

2.5 star property
Keokuk
7.8 out of 10, Good, (111)
"The daily cleaning and room care amazed us. Totally over the top service. "
United States
Robert
$60 nightly
The price is $67
Dec 10 - Dec 11
Total with taxes and fees
Chief Motel
Lobby
Super 8 by Wyndham Fort Madison

Super 8 by Wyndham Fort Madison

2.0 star property
Fort Madison
6.8 out of 10, (324)
"I would definitely stay there again!"
United States
Marcia
$65 nightly
The price is $73
Dec 10 - Dec 11
Total with taxes and fees
Super 8 by Wyndham Fort Madison
Free daily buffet breakfast
Hampton Inn Keokuk

Hampton Inn Keokuk

2.5 star property
Keokuk
8.8 out of 10, Excellent, (640)
"Very good stay. I’ll definitely stay there again "
United States
Tammy
$91 nightly
The price is $102
Jan 2 - Jan 3, 2026
Total with taxes and fees
Hampton Inn Keokuk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southeast Iowa

Showing deals for:Dec 19 - Dec 21

Image gallery for Fun City Resort Hotel

Water park

Fun City Resort Hotel

3.5 star property
Burlington
8.4/10Very Good (294 reviews)
Member Price available
$161 nightly
Price is $377
Total with taxes and fees
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Fun City Resort Hotel
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Stay near popular Southeast Iowa attractions

Joseph Smith Historic Site

4.5/5 (86 reviews)
You can learn about the history of Nauvoo when you stop by Joseph Smith Historic Site. While you're in the area, stroll along the riverfront.
See properties

Historic Nauvoo

4.6/5 (126 reviews)
Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.
See properties

Learn more about Southeast Iowa

Experience the family-friendly area of Southeast Iowa—a scenic riverfront, shopping, and sights from Battle of Athens State Historic Site to Bentonsport National Historic District.

See all hotels in Southeast Iowa
Found this bridge while exploring. It used to be a railroad bridge, transformed to a buggy bridge, and not after restoration is a walking path bridge. It stretches over a hundred feet and while walking you can still see the old railroad and boards for the buggy.
Photo by Michael Schuier
Open Photo by Michael Schuier

Top Southeast Iowa Hotel Reviews

AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

10/10 Excellent
"Room was very clean and bathroom fixtures were up to date. Breakfast was better than average and fresh. Very quiet. Didn't use pool, but it was open late and looked fresh and clean."
Bob 1-night trip
Posted 3 days ago
AmericInn by Wyndham Mount Pleasant

More cheap stays in Southeast Iowa

Comfort Suites Burlington

Comfort Suites Burlington

1780 Stonegate Center Dr Burlington IA
$110 nightly
The price is $124 total per night from Dec 21 to Dec 22
$124 total
Dec 21 - Dec 22
Total with taxes and fees
8.6/10 Excellent! (738 reviews)

Hotels in Southeast Iowa with star-rating