Cheap Flights from Chicago (ORD) to Sikeston (SIK)

Popular airlines from Chicago O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal)

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Alternative airports near Sikeston

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Cape Girardeau Municipal CGI. Cheapest option available. Average driving time to city center is 33 minutes. Flights from $139
CGI
Cape Girardeau Municipal
Cheapest
Average driving time to city center33 min
Flights from $139
Flights from Chicago (ORD) to Sikeston (SIK)
Origin airport
O'Hare Intl.
Destination airport
Sikeston Memorial Municipal
Distance
362 mi

Chicago to Sikeston Flights

The cheapest times to fly from Chicago to Sikeston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Sikeston are during the month of . You can find some of the cheapest flights from Chicago to Sikeston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Sikeston

Sunday is one of the best days to book for cheap flights from Chicago to Sikeston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Sikeston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Sikeston in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Sikeston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Sikeston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal) cost?
Secure a cheap one-way flight or cheap return flight from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal)?
Planning your trip for is a great way to save, as it's the cheapest month for flights between ORD and SIK. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from ORD to SIK. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal)?
Nonstop flights from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from ORD to SIK?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* But this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal)?
To reach Sikeston, MO (SIK-Sikeston Memorial Municipal) on time, choose a flight that takes off from O'Hare Intl. Airport (ORD) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Sikeston from O'Hare Intl. Airport (ORD)?
Cape Girardeau Municipal Airport (CGI) is the only airport in Sikeston with direct flights from O'Hare Intl. Airport (ORD). Compare the options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal) last-minute?
Last-minute fares from ORD to SIK are usually more expensive. To lock in the lowest prices, start looking for flights as early as possible. That being said, if you can play around with your travel dates, you may score a cheap fare right before your trip.
Is it cheaper to book an ORD to SIK flight and hotel package?
Compared with arranging hotels and flights separately, booking an ORD to SIK flight and hotel package with Expedia could lead to significant savings. Better still, managing everything in one place takes the hassle out of planning your trip. Simply secure your flights and choose from our extensive range of stays, then tailor your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from O'Hare Intl. Airport (ORD) to Sikeston, MO (SIK-Sikeston Memorial Municipal)?
Typically, it's possible to cancel or reschedule your ORD to SIK flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

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