$95 Cheap Flights from Tampa (TPA) to Des Moines (DSM)

View $95 flight on Mon, Nov 3, 2025Opens in a new window

Popular airlines from Tampa Intl. Airport (TPA) to Des Moines International Airport (DSM)

Cheap Flights from Tampa to Des Moines (TPA-DSM)

Prices were available within the past 7 days and start at $95 for one-way flights and $170 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, Nov 5 - Mon, Nov 10
TPA
Tampa
DSM
Des Moines
$170 Roundtrip, found 22 hours ago
$170
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Wed, Nov 5 from Tampa to Des Moines, returning Mon, Nov 10, priced at $170 found 22 hours ago
Frontier Airlines
Mon, Nov 10 - Thu, Nov 13
TPA
Tampa
DSM
Des Moines
$200 Roundtrip, found 11 hours ago
$200
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Mon, Nov 10 from Tampa to Des Moines, returning Thu, Nov 13, priced at $200 found 11 hours ago
Frontier Airlines
Wed, Oct 22 - Thu, Oct 30
TPA
Tampa
DSM
Des Moines
$201 Roundtrip, found 3 days ago
$201
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Oct 22 from Tampa to Des Moines, returning Thu, Oct 30, priced at $201 found 3 days ago
Frontier Airlines
Wed, Oct 29 - Mon, Nov 10
TPA
Tampa
DSM
Des Moines
$227 Roundtrip, found 1 day ago
$227
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Oct 29 from Tampa to Des Moines, returning Mon, Nov 10, priced at $227 found 1 day ago
Frontier Airlines
Sun, Nov 9 - Mon, Nov 17
TPA
Tampa
DSM
Des Moines
$238 Roundtrip, found 1 day ago
$238
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Nov 9 from Tampa to Des Moines, returning Mon, Nov 17, priced at $238 found 1 day ago
Frontier Airlines
Mon, Nov 10 - Mon, Nov 17
TPA
Tampa
DSM
Des Moines
$245 Roundtrip, found 22 hours ago
$245
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Mon, Nov 10 from Tampa to Des Moines, returning Mon, Nov 17, priced at $245 found 22 hours ago
American Airlines
Sat, Feb 14 - Fri, Feb 20
TPA
Tampa
DSM
Des Moines
$261 Roundtrip, found 1 day ago
$261
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Feb 14 from Tampa to Des Moines, returning Fri, Feb 20, priced at $261 found 1 day ago
Southwest Airlines
Tue, Jan 6 - Wed, Jan 7
TPA
Tampa
DSM
Des Moines
$261 Roundtrip, found 1 day ago
$261
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Jan 6 from Tampa to Des Moines, returning Wed, Jan 7, priced at $261 found 1 day ago
Delta
Tue, Jan 6 - Wed, Jan 7
TPA
Tampa
DSM
Des Moines
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jan 6 from Tampa to Des Moines, returning Wed, Jan 7, priced at $263 found 1 day ago
United
Thu, Dec 11 - Mon, Dec 15
TPA
Tampa
DSM
Des Moines
$284 Roundtrip, just found
$284
Roundtrip
just found
Select United flight, departing Thu, Dec 11 from Tampa to Des Moines, returning Mon, Dec 15, priced at $284 just found

Find the cheapest month to fly from Tampa (TPA) to Des Moines (DSM)

November is typically the cheapest month to fly

From $128 - $499 per traveler.

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $335
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $335

Frequently asked questions

How much does a flight from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM) cost?
Grab a cheap one-way flight from $95 or cheap return flight from $170 from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM)?
Traveling in November can help you save, as it's the cheapest month for flights between TPA and DSM. You'll usually find the lowest fares during the off-season.
Which airlines fly direct from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM)?
You can't catch a nonstop flight to Des Moines Intl. Airport (DSM) from Tampa, FL (TPA-Tampa Intl.). However, you can seamlessly travel to Des Moines without any layovers by leaving from Sarasota-Bradenton Intl. Airport (SRQ).
What is the cheapest airline that flies from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll fly you from TPA to DSM. Then, sort your results by "Price (lowest to highest)" to snag the best deal available.
How many flights per day from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM)?
There aren't any daily direct flights from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be soaring above the clouds before you know it.
What day of the week has the most flights from TPA to DSM?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM)?
To touch down at Des Moines Intl. Airport (DSM) without delays, pick a flight that leaves from Tampa Intl. Airport (TPA) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM) last-minute?
Booking your flight from TPA to DSM shortly before your journey is generally more expensive. But if you're flexible with your travel times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a TPA to DSM flight and hotel package?
Compared with arranging flights and hotels separately, booking a TPA to DSM flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one convenient place will take the hassle out of planning your trip. Simply secure your flights and choose from our wide range of hotels, then personalize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Tampa Intl. Airport (TPA) to Des Moines Intl. Airport (DSM)?
Usually, it's possible to cancel or reschedule your TPA to DSM flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Tampa Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$170
Distance
1126 mi

Book with confidence

Tampa to Des Moines Flights

The cheapest times to fly from Tampa to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tampa to Des Moines are during the month of November. You can find some of the cheapest flights from Tampa to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tampa to Des Moines

Sunday is one of the best days to book for cheap flights from Tampa to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tampa to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tampa to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $95 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tampa to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tampa to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Tampa to Des Moines Flights

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*Available to One Key members.