Find 2 Star Hotels in Matlacha Isles, FL from $67
Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Be picky
Search almost a million properties worldwide
Check availability on Matlacha Isles 2 Star Hotels
Compare Matlacha Isles 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
9.2 out of 10, Wonderful, (1013)
$95 nightly
The price is $106
Oct 19 - Oct 20
Total with taxes and fees

Baymont by Wyndham Fort Myers Central
Baymont by Wyndham Fort Myers Central
6.6 out of 10, (1010)
$65 nightly
The price is $72
Oct 14 - Oct 15
Total with taxes and fees

Comfort Inn & Suites Airport
Comfort Inn & Suites Airport
8.8 out of 10, Excellent, (1097)
$74 nightly
The price is $82
Oct 19 - Oct 20
Total with taxes and fees

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
7.8 out of 10, Good, (1445)
$69 nightly
The price is $77
Oct 14 - Oct 15
Total with taxes and fees

Extended Stay America Premier Suites - Fort Myers - Airport
Extended Stay America Premier Suites - Fort Myers - Airport
8.8 out of 10, Excellent, (715)
$76 nightly
The price is $85
Oct 14 - Oct 15
Total with taxes and fees

Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG
Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG
8.2 out of 10, Very Good, (957)
$97 nightly
The price is $108
Oct 18 - Oct 19
Total with taxes and fees

Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG
9.6 out of 10, Exceptional, (1009)
$95 nightly
The price is $106
Oct 19 - Oct 20
Total with taxes and fees

Baymont by Wyndham Punta Gorda/Port Charlotte
Baymont by Wyndham Punta Gorda/Port Charlotte
8.2 out of 10, Very Good, (1071)
$80 nightly
The price is $90
Oct 14 - Oct 15
Total with taxes and fees
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Matlacha Isles.

Lani Kai Beachfront Resort
1400 Estero Blvd, Fort Myers Beach, FL
$189 nightly
The price is $211 total per night from Oct 16 to Oct 17
$211 total
Oct 16 - Oct 17
Total with taxes and fees
8.8/10 Excellent! (1,033 reviews)
Still don't see what you're looking for?
See all properties in Matlacha Isles.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Matlacha Isles Hotel Reviews

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
10/10 Excellent
Explore a world of travel with Expedia
- Matlacha Isles-Matlacha Shores Hotels
- 4 Star Hotels in Matlacha
- Hotels near Griffen American Center for Haitian Art
- Matlacha Hotels
- Villas in Matlacha
- Cottages in Matlacha
- Oceanfront Hotels in Matlacha
- Resorts in Matlacha
- Houseboats in Matlacha
- Motels in Matlacha
- Fishing Resorts & in Matlacha
- All-inclusive Resorts in Matlacha
- RV Parks in Matlacha
- Historic Hotels in Matlacha
- Hotels with an Outdoor Pool in Matlacha
- Cabin Rentals in Matlacha
- Best Western Hotels in Matlacha
- B&B in Matlacha
- Pet-friendly Hotels in Matlacha
- Luxury Hotels in Matlacha
- Family Hotels in Matlacha
- Hotel Wedding Venues Hotels in Matlacha
- Hotels with a Pool in Matlacha
- Vacation Homes in Matlacha
- Romantic Hotels in Matlacha
- Hotels near Lovegrove Gallery & Gardens
- Hotels near Royal Tee Golf Club
- Hotels near Trafalgar
- Gay friendly Hotels in Trafalgar
- Hotels near Burnt Store
- Hotels near Coral Oaks Golf Course
- Hotels near Palmetto-Pine Country Club
- Hotels near Sun Splash Water Park
- 5 Star Hotels in Pine Island
- 4 Star Hotels in Pine Island
- Hotels near Mariner
- Pine Island Center Hotels
- Hotels near Bowland Coral Lanes
- Pine Island Hotels
- Beach Hotels in Pine Island
- Luxury Hotels in Pine Island
- Motels in Pine Island
- Fishing Resorts & in Pine Island
- Pet-friendly Hotels in Pine Island
- Historic Hotels in Pine Island
- Hotels near Mike Greenwell's Bat-A-Ball & Family Fun Park
- Hotels near Hunters Run Executive Golf Course
- Hotels near Pelican
- Hotels near Cape Coral Historical Museum
- Hotels near Lee Island
- Hotels near Randell Research Center
- Florida Gulf Coast Hotels
- Hotels near Hancock
- Luxury Hotels in Florida Gulf Coast
- Hotels near HeadPinz Family Entertainment Center
- Hotels near Cape Harbour
- Griffen American Center for Haitian Art
- Visit Matlacha
- Matlacha Vacations
- Lovegrove Gallery & Gardens
- Royal Tee Golf Club
- Visit Burnt Store
- Coral Oaks Golf Course
- Palmetto-Pine Country Club
- Sun Splash Water Park
- Koucky Gardens & Gallery
- Museum of the Islands
- Bowland Coral Lanes
- Visit Pine Island
- Mike Greenwell's Bat-A-Ball & Family Fun Park
- Hunters Run Executive Golf Course
- Visit Pelican
- Lee Island
- Calusa Heritage Trail
- Florida Gulf Coast Vacations
- Visit Hancock
- HeadPinz Family Entertainment Center
- Car rentals near Matlacha Isles-Matlacha Shores
- Car rentals near Matlacha
- Car rentals near Pine Island Center
- Enterprise Rental Cars in Pine Island
- Car rentals near Pine Island
- Alamo Rent A Car Rental Cars in Pine Island
- Offer Car Hire Rental Cars in Pine Island
- Hertz Rental Cars in Pine Island
- Advantage Rent-A-Car Rental Cars in Pine Island
- Hawk Rental Cars in Pine Island
- Car rentals near Mike Greenwell's Bat-A-Ball & Family Fun Park
- Car rentals near Flamingo Bay
- Car rentals near Alden Pines
- Car rentals near HeadPinz Family Entertainment Center