The Best 5 Star Hotels in Biloxi, MS from $99

A beach with wooden chairs and colorful umbrellas, a pier extending into the water, and a lifeguard tower in the background.

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Biloxi.

IP Casino Resort Spa - Biloxi

850 Bayview Ave Biloxi MS

$88 nightly

$99 total

Nov 11 - Nov 12

Total with taxes and fees

8.8/10 Excellent! (5,019 reviews)

Hard Rock Hotel & Casino Biloxi

777 Beach Blvd. Biloxi MS

Get rates

8.4/10 Very Good! (5,356 reviews)

Scarlet Pearl Casino Resort

9380 Central Ave D'Iberville MS

$91 nightly

$102 total

Oct 26 - Oct 27

Total with taxes and fees

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Biloxi and related destinations

White sand beaches invite you to relax while historic casinos offer a chance at Lady Luck's favor. Seafood shacks serve fresh Gulf catches, and the Biloxi Lighthouse stands as a resilient symbol of coastal charm.

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Top Biloxi Hotel Reviews

Find out more about Biloxi

Ready to experience the next standard in luxury? We know you're thinking about it. Pamper your every desire on your upcoming sabbatical. There's no reason to delay a getaway to Biloxi any longer. You'll join the multitudes of vacationers who have made Biloxi so fashionable recently. Additionally, the hotels in this area are known for customer service, so you know you'll be well cared for during your getaway. Don't wait any longer. Reserve one of our 5-star hotels in Biloxi and indulge in the finer things in life for a while.

Book the Best Biloxi 5-Star Hotels

Don't be afraid to be pampered during your trip, along with pristine rooms. High-end restaurants, excellent customer care, and fabulous spa offerings are all on offer. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. Additionally, the hotels in this area receive high marks for customer satisfaction, so you know you'll be looked after during your getaway. How do you want to relax? A deep-tissue massage to help your cares fall away? A concierge to help you plan every detail of your day? Comfortable beds, piping hot coffees, and even spectacular views...these hotels will leave you amazed. Want to see for yourself? Then explore the 1,550 reviews various guests have left on Expedia and get to know these places.

You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Biloxi are the perfect place to rest up after a busy day.

Your Getaway Starts Today

The results are in, and Biloxi 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Decide on one of the 5-star hotels in Biloxi today and relax in complete comfort tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Biloxi?

The amount you pay for a 5-star hotel in Biloxi can vary depending on what time of year you travel and how long you plan to stay, among a range of factors. Take advantage of our price per night filter and other search tools to land the best rate on a luxurious getaway.

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What makes a hotel 5 stars in Biloxi?

Exceptional guest service is integral to every 5-star hotel in Biloxi. From the moment you enter the lobby, staff cater to your every whim, whether recommending activities and tours or providing a turn-down service. Additionally, hotels must offer top-rate conveniences to be entitled to a 5-star rating. These can include luxury bathrooms, an on-site spa, pools, gastronomic kitchens and knowledgeable concierge.

Are there any 5-star all-inclusive resorts in Biloxi?

Expedia's filter tool is the quickest way to find exactly what you want. Select "5-star" and "All inclusive" to show the finest resorts in Biloxi where your meals, accommodations, activities and entertainment are included in the upfront price. At these stays, your trip is pure extravagance from the moment you put down your suitcase.

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