A tropical island with palm trees and a clear blue sky.

Cheap Flights to Panama from $218

View $218 flight on Tue, Nov 24, 2026Opens in a new window

Popular airlines to Panama

  • Avianca

  • American Airlines

  • United

  • Copa

  • Delta

  • Aeromexico

  • KLM

How much is the cheapest flight to Panama?

Prices were available within the past 7 days and start at $218 for one-way flights and $455 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Copa
Copa
United
American Airlines
Copa
United
Copa
avianca
Aeromexico

Airports in Panama

Prices were available within the past 7 days. Prices and availability are subject to change.

Trending flights to Panama

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa

Book with confidence

Enjoy extra legroom, flight flexibility, and a seamless travel experience.

Travel information

*Flight schedules are subject to change.

*Available to One Key members.

*Flight schedules are subject to change.

*Available to One Key members.

Explore a world of travel with Expedia