A tropical island with palm trees and a clear blue sky.
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Panama Vacations & Trips from $854

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Top destinations in Panama

The Latest Panama Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Sep 1 - Sep 4

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen
    3 nights
    4.0 star property
    8.4/10 - Very Good (1,808 reviews)
    "si tienes que hacer escala en panama. este lugar es perfecto. super cerca. te da transporte de aeropuerto hotel y viceversa. Y me toco comer ahi y todo rico. Dormi bien y volveria para ir de compras a panama"
    Reviewed July 19, 2026
    Roundtrip New York (EWR) - Panama City (PTY)
    JFK - PTYNonstop PTY - JFKNonstop
    $1,118
    $854
    per traveler
    found 1 day ago
    Riande Aeropuerto Hotel & Casino
  • Sep 24 - Sep 30

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    6 nights
    4.0 star property
    9.2/10 - Wonderful (1,000 reviews)
    "We only stayed for one night but had a great overall experience. Staff were very helpful and courteous. The hotel amenities were high quality and our room was very clean. The only "con" to report is that the hotel could use a little TLC in some areas."
    Reviewed July 12, 2026
    Roundtrip New York (EWR) - Panama City (PTY)
    JFK - PTYNonstop PTY - JFKNonstop
    Save 100% on your flight
    $2,352
    $1,258
    per traveler
    found 2 days ago
    Central Hotel Panama Casco Viejo
  • Sep 20 - Sep 25

    Megapolis Hotel Panamá + Flight

    San Francisco
    5 nights
    4.5 star property
    8.4/10 - Very Good (1,599 reviews)
    "Excelente"
    Reviewed July 19, 2026
    Roundtrip New York (EWR) - Panama City (PTY)
    JFK - PTYNonstop PTY - JFKNonstop
    Save 100% on your flight
    $1,759
    $1,033
    per traveler
    found 1 day ago
    Megapolis Hotel Panamá
  • Sep 27 - Oct 3

    Hotel Riu Playa Blanca - All Inclusive + Flight

    Rio Hato
    6 nights
    3.5 star property
    8.0/10 - Very Good (1,000 reviews)
    "Clean room"
    Reviewed July 16, 2026
    Roundtrip New York (EWR) - Rio Hato (RIH)
    EWR - PTYNonstop PTY - EWRNonstop
    $1,655
    $1,190
    per traveler
    found 6 hours ago
    Hotel Riu Playa Blanca - All Inclusive
  • Sep 20 - Sep 25

    Hotel Riu Plaza Panama + Flight

    Bella Vista
    5 nights
    5.0 star property
    9.0/10 - Wonderful (5,731 reviews)
    "I was at the hotel for a conference, and they made each aspect of my day, before, during, and after work so enjoyable. Plus, the breakfast buffet was so impressive."
    Reviewed July 19, 2026
    Roundtrip New York (EWR) - Panama City (PTY)
    JFK - PTYNonstop PTY - JFKNonstop
    $1,295
    $943
    per traveler
    found 1 day ago
    Hotel Riu Plaza Panama

Discover the most popular places to visit in Panama

What to do in Panama

Panama Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Panama vacation package cost?

Say yes to new adventures with our Panama vacation packages, which start from only $854. Pick the flights and hotels that suit your style. Then, add on some tours or activities to cap off your unique adventure.

How do I get a cheap travel package to Panama?

Booking a hotel and flight together with Expedia won't just save you time — it'll save you a nice amount too. A Panama vacation package makes it a cinch to arrange the ideal trip. With more than 550 airlines all over the world to pick from, finding convenient flights that fit your schedule won't be an issue. On top of that, we've got over 1,000,000 hotel options globally to choose from. Now that's choice! Whatever your budget, Expedia puts more of the world within your reach.

Where should I stay in Panama?

To see terrific sights like Miraflores Locks and Metropolitan Cathedral of Panama, Panama City is the place to be. Plenty of travelers also enjoy spending time in Panama Canal Zone, home to Miraflores Locks and Gatun Locks. If you've got an extended vacation in Panama, why not check out both cities?

What are the top hotels in Panama?

Look up Hotel Riu Plaza Panama and Crowne Plaza Panama Airport, an IHG Hotel. They're the first choice for many travelers headed to Panama City. If Bocas del Toro features in your travel itinerary, Divers Paradise Boutique Hotel and La Coralina Island House are both top-notch options.

How far in advance should I book my Panama vacation?

Reserving your seat early with Expedia means one less thing to have to worry about. Most air carriers display prices up to 12 months in advance. This is generally the cheapest time to book. If circumstances have left you booking late, low prices to Panama sometimes occur a few weeks before departure.

What does an Expedia Panama travel package include?

That depends on what you're after. If you're traveling solo, you might decide to combine flights and hotels. Taking the whole family to Panama? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to tailor your travel package.

What should I know before booking a Panama travel package?

You'll enjoy amazing savings when you combine your hotels, flights and rental cars into a package. Plus, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget solo adventure, explore our package deals today.

Can I choose my airline with a Panama Expedia vacation package?

Yes — that's one of the best things about an Expedia package. You get to choose. We have more than 550 airline partners globally, so you have options galore when creating your Panama getaway.

Does Expedia offer Book Now, Pay Later Panama vacation packages?

Having teamed up with online lender Affirm, Expedia provides financial flexibility with a Book Now, Pay Later option for hotel and activities packages. Get the money side of things out of the way with an upfront payment or split the cost of your getaway over multiple installments. There's a payment option to suit every wanderer.

If I'm not able to travel, can I cancel my Panama vacation package?

Because we understand life is full of surprises, the answer is yes. For further information, check out our Customer Service Portal. But generally speaking, if you've booked your package in the last 24 hours, you may be able to change or cancel it without penalty. Your airline, hotel or car rental company may charge a fee if your booking is older than that.

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Things to do in Panama

Panama is a fantastic destination for beach lovers, families, and city explorers alike. Visitors can enjoy a variety of activities including shopping at vibrant malls and relaxing at resorts. Essential experiences include guided tours of Panama City, thrilling adventures, and day trips to explore the stunning landscapes. With so much to offer, Panama promises an unforgettable vacation filled with excitement and discovery.

Shopping

For a great shopping experience in Panama, visit Albrook Shopping Mall for a mix of entertainment and family-friendly vibes. Explore Uruguay Street for unique boutiques and local shops. Don’t miss the Sunday Market, a vibrant spot for local crafts and fresh produce, perfect for souvenirs.

Recreation

At Estadio Rommel Fernandez, immerse yourself in the energetic sports atmosphere, perfect for active enthusiasts. La Casa de Lourdes Outdoor Spa invites you to unwind with soothing body treatments in a serene setting. For culture lovers, the Boquete Community Players Theater offers delightful performances in a romantic, family-friendly venue.

Adventure

Explore the breathtaking Sendero El Pianista hiking trail, where stunning views and lush scenery await outdoor enthusiasts. Enjoy thrilling water slides and family fun at Parque Acuatico Italia Guadalupe. Dive into adventure with underwater sports at Coral Dreams, perfect for adrenaline seekers and ocean lovers alike.

Nightlife

Panama City boasts a vibrant nightlife with a mix of clubs and bars. Visit the rooftop bar at Tantalo for stunning views and creative cocktails. For dancing, head to La Casa del Marisco, where you can enjoy lively music and a fun atmosphere that keeps the party going all night.

Find the best attractions in Panama

Panama offers an ideal getaway for beach lovers, families, and city explorers alike. With stunning beaches, national parks, and urban parks, there's something for everyone. Key attractions include the iconic Panama Canal and a rich cultural scene. Whether you're seeking outdoor adventures or a relaxing beach experience, Panama's diverse offerings ensure a memorable vacation for every traveler.

  • Playa Blanca: Enjoy the sun and surf at Playa Blanca, a stunning beach known for its beautiful white sands and crystal-clear waters. Perfect for relaxation or beach activities, it offers a vibrant atmosphere that's ideal for families and friends seeking fun in the sun.
  • Cinta Costera: This urban park is a delightful blend of nature and city life. Stroll or bike along its scenic pathways, enjoy waterfront views, and engage in outdoor activities. Cinta Costera is perfect for families, offering playgrounds and picnic areas amidst stunning cityscapes.
  • Avenida Balboa: As one of Panama City's main thoroughfares, Avenida Balboa showcases the city's modern vibe. Explore its shops, restaurants, and waterfront promenades while soaking in the lively atmosphere and beautiful views of the Panama Bay.

Best time to go to Panama

The best time to visit Panama can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Panama falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Panama falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

Tips to save on your trip to Panama

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Panama.
  • Consider traveling to Panama during the low season (September to November) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.