Business Hotels in South Carolina from $55
- Upfront pricingOur total price for your stay includes taxes and fees
- Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
- Be pickySearch almost a million properties worldwide
Check availability on South Carolina Business Hotels
Pick from 824 South Carolina Business Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Inn Greenville - Haywood Mall
Greenville
8.0 out of 10, Very Good, (1005)
$93 nightly
The price is $102
Nov 9 - Nov 10
Total with taxes and fees

Hyatt Place Charleston Airport/Convention Center
North Charleston
9.4 out of 10, Exceptional, (1126)
$96 nightly
The price is $109
Nov 16 - Nov 17
Total with taxes and fees

Sheraton Columbia Downtown Hotel
Downtown Columbia
8.4 out of 10, Very Good, (1002)
$107 nightly
The price is $120
Nov 24 - Nov 25
Total with taxes and fees

Town & Country Inn and Suites
West Ashley
9.2 out of 10, Wonderful, (1559)
$149 nightly
The price is $170
Nov 9 - Nov 10
Total with taxes and fees

Sleep Inn at Greenville Convention Cente
Greenville
8.0 out of 10, Very Good, (1001)
$82 nightly
The price is $90
Nov 16 - Nov 17
Total with taxes and fees

La Quinta Inn & Suites by Wyndham Greenville Haywood
Greenville
7.4 out of 10, Good, (1102)
$68 nightly
The price is $75
Nov 9 - Nov 10
Total with taxes and fees

Home2 Suites by Hilton Greenville Downtown
Greenville Downtown
9.2 out of 10, Wonderful, (993)
$107 nightly
The price is $118
Nov 24 - Nov 25
Total with taxes and fees

Hyatt Place Greenville/Haywood
Greenville
7.8 out of 10, Good, (1000)
$80 nightly
The price is $88
Nov 29 - Nov 30
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top South Carolina Hotel Reviews

Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG
10/10 Excellent
Explore a world of travel with Expedia
- Columbia Hotels
- Cheap Hotels in Columbia
- Luxury Hotels in Columbia
- Pet-friendly Hotels in Columbia
- Hotels near Downtown Columbia
- Hotels with Restaurants in Downtown Columbia
- Hotels with an Indoor Pool in Columbia
- Hotels with a View in Downtown Columbia
- Hotels with Free Breakfast in Downtown Columbia
- Hotels with Connecting Rooms in Downtown Columbia
- Historic Hotels in Downtown Columbia
- Hotels with Room Service in Downtown Columbia
- Hotels with Hot Tubs in Downtown Columbia
- Hotels with Suites in Downtown Columbia
- Luxury Hotels in Downtown Columbia
- Hotels with Bars in Downtown Columbia
- Pet-friendly Hotels in Downtown Columbia
- Hotels with an Outdoor Pool in Downtown Columbia
- Hotels with Free Parking in Downtown Columbia
- Hotels with a Gym in Downtown Columbia
- Hotels with Kitchenettes in Downtown Columbia
- Hotels with an Indoor Pool in Downtown Columbia
- Hotels with Balconies in Downtown Columbia
- Hotels with Laundry Facilities in Downtown Columbia
- Resorts & Hotels with Spas in Downtown Columbia
- Honeymoon Resorts & in Downtown Columbia
- Hotel Wedding Venues Hotels in Downtown Columbia
- Hotels with a Pool in Downtown Columbia
- Cheap Hotels in Downtown Columbia
- Hotels with Suites in Columbia
- Hotels with Balconies in Columbia
- Hotels with Hot Tubs in Columbia
- Resorts & Hotels with Spas in Columbia
- Hotels with Free Airport Shuttle in Columbia
- Hotels with smoking rooms in Columbia
- Hotels with Connecting Rooms in Columbia
- Honeymoon Resorts & in Columbia
- Hotels with Kitchenettes in Columbia
- Boutique Hotels in Columbia
- Hotels with Early Check-in in Columbia
- Hotel Wedding Venues Hotels in Columbia
- Hotels with Bars in Columbia
- Hotels with Restaurants in Columbia
- Hotels with Free Breakfast in Columbia
- Hotels with a Gym in Columbia
- Beach Hotels in Columbia
- Romantic Hotels in Columbia
- Hotels with an Outdoor Pool in Columbia
- Casino Hotels in Columbia
- Hotels with an Indoor Pool in The Vista
- Hotels with Free Parking in The Vista
- Luxury Hotels in The Vista
- Hotels with an Outdoor Pool in The Vista
- Hotel Wedding Venues Hotels in The Vista
- Extended Stay Hotels in Columbia
- Family Hotels in Columbia
- Historic Hotels in Columbia
- Adults Only Resorts & in Columbia
- Hotels with Room Service in Columbia
- Hotels on the Lake in Columbia
- Golf Hotels in Columbia
- Hotels with Laundry Facilities in Columbia
- Hotels with Free Parking in Columbia
- Hotels with a Pool in Columbia
- Hotels with Fireplaces in Columbia
- Business Hotels in Columbia
- Hotels with a View in Columbia
- Non-Smoking Hotels in Columbia
- Quiet Resorts & in Columbia
- Hotels with Tennis Courts in Columbia
- Hotels & Resorts for Couples in Columbia
- Hotel with a Concierge Hotels in Columbia
- Hotels with Air Conditioning in Columbia
- Green Hotels in Columbia
- Fishing Resorts & in Columbia
- Hotels near University of South Carolina
- 5 Star Hotels in Downtown Columbia
- 3 Star Hotels in Downtown Columbia
- Hotels near South Carolina State House
- Hotels near Trinity Episcopal Cathedral
- Hotels near Town Theatre
- Hotels near Colonial Life Arena
- Motels in Columbia
- Hotels near Columbia Metropolitan Convention Center
- The Vista Hotels
- 5 Star Hotels in Columbia

















































