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Our top choices for Effingham hotels

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,759 reviews)
"Quiet clean and inexpensive stay, especially relative to neighboring locations"
United States
Carl
$65 nightly
The price is $72
Nov 9 - Nov 10
Total with taxes and fees
Howard Johnson by Wyndham Florence

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,501 reviews)
"Great place to spend the night during our road trip. Would stay again."
United States
Susan
$90 nightly
The price is $101
Nov 15 - Nov 16
Total with taxes and fees
Park Inn by Radisson Florence, SC

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,394 reviews)
"Comfortable beds and clean environments."
United States
Steven
$101 nightly
The price is $113
Nov 29 - Nov 30
Total with taxes and fees
Comfort Inn & Suites Florence Center Area

4. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,004 reviews)
"The room was clean and the breakfast was good"
United States
Ana Maria
$116 nightly
The price is $130
Nov 15 - Nov 16
Total with taxes and fees
Hyatt Place Florence Downtown

5. The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.6 out of 10, Exceptional, (1,005 reviews)
"Excellent stay. A little overpriced for the area. But nice hotel."
United States
Winston
$121 nightly
The price is $136
Dec 9 - Dec 10
Total with taxes and fees
The Inn at the Crossroads

6. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.4 out of 10, Very good, (426 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
$89 nightly
The price is $100
Nov 15 - Nov 16
Total with taxes and fees
Quality Inn & Suites Florence Civic Center

7. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.4 out of 10, Very good, (356 reviews)
"Great staff easy Check in I love staying here!!!"
United States
Alanya
$102 nightly
The price is $114
Nov 15 - Nov 16
Total with taxes and fees
Spark by Hilton Florence North I-95, SC

8. Courtyard by Marriott Florence

Courtyard by Marriott Florence
3.0 star property
Florence
7.8 out of 10, Good, (773 reviews)
"Great place to stay!!!"
United States
Willie
$111 nightly
The price is $124
Nov 15 - Nov 16
Total with taxes and fees
Courtyard by Marriott Florence

9. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (659 reviews)
"The house keeping people"
United States
WILLIE
$139 nightly
The price is $155
Nov 15 - Nov 16
Total with taxes and fees
Hotel Florence, Tapestry Collection by Hilton

10. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.0 out of 10, Wonderful, (664 reviews)
"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"
United States
Alma
$118 nightly
The price is $132
Nov 12 - Nov 13
Total with taxes and fees
Fairfield Inn & Suites by Marriott Florence I-20

11. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.2 out of 10, Very good, (1,002 reviews)
"Staff is so helpful hotel is very clean well kept"
United States
Tom
$108 nightly
The price is $121
Nov 11 - Nov 12
Total with taxes and fees
SpringHill Suites by Marriott Florence

12. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay great breakfast clean"
United States
Zachary
$122 nightly
The price is $137
Dec 6 - Dec 7
Total with taxes and fees
Staybridge Suites Florence - Civic Center by IHG

13. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice and clean hotel"
United States
HANH
$114 nightly
The price is $128
Nov 22 - Nov 23
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

14. Affordable Suites Florence

Affordable Suites Florence
2.5 star property
Florence
9.2 out of 10, Wonderful, (232 reviews)
"Location is awesome and near everything the staff are very friendly and kind will definitely be coming back for more hotel stays"
United States
Cheyenne
$74 nightly
The price is $82
Dec 9 - Dec 10
Total with taxes and fees
Affordable Suites Florence

15. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (925 reviews)
"Fabulous pet-friendly place to stay."
United States
Ralph
$110 nightly
The price is $123
Nov 9 - Nov 10
Total with taxes and fees
TownePlace Suites by Marriott Florence

16. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.6 out of 10, Excellent, (1,002 reviews)
"Great hotel and staff"
United States
Margarita
$115 nightly
The price is $129
Nov 15 - Nov 16
Total with taxes and fees
Tru by Hilton Florence I-95

17. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,456 reviews)
"Close to the restaurants and shopping."
United States
Brenda
$89 nightly
The price is $100
Nov 22 - Nov 23
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Florence

18. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Good location, clean room and good breakfast."
United States
NOORUDIN
$114 nightly
The price is $128
Nov 15 - Nov 16
Total with taxes and fees
Hampton Inn & Suites Florence Center

19. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellente hotel, clean, good breakfast, and quiet."
Canada
chantal
$114 nightly
The price is $128
Nov 24 - Nov 25
Total with taxes and fees
Hampton Inn & Suites Florence-North-I-95

20. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,001 reviews)
"Good location- very good free breakfast"
United States
Christopher
$135 nightly
The price is $151
Dec 7 - Dec 8
Total with taxes and fees
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Effingham Hotel Reviews

Frequently Asked Questions

What is the best area to stay in Effingham?

The best area to stay in Effingham is near the intersection of US-301 and I-95, as this offers the most convenient access to amenities and onward travel.

This area is primarily characterized by its array of hotels, restaurants, and gas stations, strategically located for travelers passing through or needing a stopover. You'll find most services concentrated along US-301, just off the I-95 exits. While not a tourist destination in itself, it provides all the necessary conveniences for a comfortable stay.

For solo travelers or couples on a road trip, this location is ideal. It offers quick access to the interstate, making it easy to continue your journey. The concentration of dining options, from casual eateries to sit-down restaurants, provides variety without requiring extensive travel.

When is the best time to go to Effingham?

The best time to visit Effingham, South Carolina, is during the spring (March to May) and fall (September to November) months.

These seasons offer pleasant weather with mild temperatures, ideal for enjoying outdoor activities without the intense heat and humidity of summer or the cooler, sometimes unpredictable, temperatures of winter. Spring brings blooming flora, while fall showcases colorful foliage, making for scenic drives and comfortable exploration of the local area.

For travelers who prefer warm weather and don't mind higher humidity, the summer months (June to August) are also an option. During this time, the days are long, allowing for extended outdoor enjoyment, though afternoon thunderstorms can occur.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.

How much is the nightly rate at a Effingham hotel?

Prices for hotels in Effingham often vary, but you can find a great deal from $72 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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