Title: TOP 10 Hotels in Pamplico, SC (from $61) - COMPETITIVE PRICES | Expedia.com [Pamplico Travel Guide](https://expedia.com/Pamplico.dx3000353197)[Vacation Rentals in Pamplico](https://expedia.com/Pamplico-Vacation-Rentals.d3000353197.Travel-Guide-VacationRentals)[Flights to Pamplico](https://expedia.com/Cheap-Flights-To-Pamplico.d3000353197.Travel-Guide-Flights)[Things to do in Pamplico](https://expedia.com/Things-To-Do-In-Pamplico.d3000353197.Travel-Guide-Activities)[Car Rentals in Pamplico](https://expedia.com/Car-Rentals-In-Pamplico.d3000353197.Car-Rental-Guide)[Pamplico Vacation Packages](https://expedia.com/Pamplico.d3000353197.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Pamplico Pool [](https://www.expedia.com/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-04-10&d1=2026-04-10&endDate=2026-04-12&d2=2026-04-12&amenities=POOL) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-04-10&d1=2026-04-10&endDate=2026-04-12&d2=2026-04-12&travelerType=family_friendly) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-04-10&d1=2026-04-10&endDate=2026-04-12&d2=2026-04-12&amenities=PETS) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-04-10&d1=2026-04-10&endDate=2026-04-12&d2=2026-04-12&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2026-04-10&d1=2026-04-10&endDate=2026-04-12&d2=2026-04-12&lodging=APARTMENT) ## Check prices for these dates Tonight [Mar 27 - Mar 28](https://www.expedia.com/Hotel-Search?regionId=3000353197&startDate=2026-03-27&endDate=2026-03-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 28 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=3000353197&startDate=2026-03-28&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=3000353197&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=3000353197&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Pamplico hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/ffaddd2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9f09eded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/bdf580c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/83cb7582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) Florence 8.6/10 Excellent (1,003 reviews) "The stay was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dianne $127 nightly $142 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | 1 bedroom, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) Florence 8.6/10 Excellent (2,600 reviews) "Very comfortable room and the hotel was close to the Interstate and many good trestaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles $60 nightly $68 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/2dfd6373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/6986f055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/a6fa48ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/b51b62f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Mullins - Marion [](https://www.expedia.com/Florence-Hotels-Quality-Inn.h24816.Hotel-Information) Marion 7.8/10 Good (394 reviews) "It was ok clean would stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeff $98 nightly $107 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Quality-Inn.h24816.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/778f48dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/8b979844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/25ba1b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/0da1bc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Executive Inn [](https://www.expedia.com/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) Latta 8.2/10 Very Good (972 reviews) "The staff at check in and the staff at check out was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jackieann $106 nightly $116 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/210000/201000/200964/c182f4e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/210000/201000/200964/ffd65bdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/201000/200964/b14a783e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/210000/201000/200964/88025fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn Timmonsville [](https://www.expedia.com/Florence-Hotels-Budget-Inn-Timmonsville.h200964.Hotel-Information) Timmonsville 7.0/10 Good (331 reviews) "Easy parking. Adequate accomdations for 1 nite." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nadine $61 nightly $68 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Budget-Inn-Timmonsville.h200964.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/3e9ccd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) Florence 9.0/10 Wonderful (880 reviews) "Busy hotel. Nice rooms awesome free breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ken $110 nightly $123 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/7942388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) Florence 9.2/10 Wonderful (604 reviews) "Great place to stay while we have long trip from FL to NY" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sergii $114 nightly $128 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0c64863b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) Florence 9.0/10 Wonderful (2,230 reviews) "Bed was comfortable and breakfast was good " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Bernard $89 nightly $100 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fad493a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a63ff680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) Florence 9.0/10 Wonderful (1,237 reviews) "Clean room, good breakfast...very nice overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerry $102 nightly $114 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/7f29240e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking (Deluxe Family Room) | Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/9ce36c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/3c3cf86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f732d5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Florence 7.8/10 Good (1,633 reviews) "Good hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $106 nightly $119 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2544034c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/fcf4fdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/5cc0357e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2a6d6c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Latta by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) Latta 9.6/10 Exceptional (568 reviews) "Great visit to this site...convenient to food, gas, and the staff was so pleasant. Breakfast was very good and I would not hesitate to stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl $118 nightly $129 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) ![Studio, Multiple Beds | Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/63709e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/e6f886e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence [](https://www.expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) Florence 9.0/10 Wonderful (786 reviews) "Place was perfect for a short stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victor $114 nightly $128 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/faf9e566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/c54591ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/b8bbf179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/73ae15f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 8.8/10 Excellent (36 reviews) "Clean, quiet and safe location to spend the night. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David $87 nightly $97 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1f011cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) Florence 7.0/10 Good (1,001 reviews) "Clean, very quiet , staff very friendly, safe place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) María $66 nightly $74 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/434898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/5054dc3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Florence 8.4/10 Very Good (1,002 reviews) "Everything was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brad $104 nightly $116 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/88f4ba4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/ee878326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) Florence 9.0/10 Wonderful (862 reviews) "Parking convenient. Room clean and bed very comfortable. Would recommend and plan to stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MG $110 nightly $123 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/2d26ec35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/73965d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/93db4fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) Florence 6.8/10 (1,002 reviews) "Friendly staff, clean room, very comfortable bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Willie $60 nightly $67 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/72ff83dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/863c7840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/dd4c54c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/2d22b260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Super-8-By-Wyndham-Florence.h861452.Hotel-Information) Florence 7.0/10 Good (1,000 reviews) "Perfect overnight spot" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martin $58 nightly $65 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Super-8-By-Wyndham-Florence.h861452.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/e2ea309a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/0e00b7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown [](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) Florence 9.0/10 Wonderful (1,003 reviews) "It was a beautiful room and breakfast was great. Staff was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie $122 nightly $137 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/87bb3ed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/078b0644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/098e0775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/18421e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Florence SC I-95 North / Hwy 76 [](https://www.expedia.com/Florence-Hotels-Travelodge-By-Wyndham-Florence.h528148.Hotel-Information) Florence 5.2/10 (359 reviews) "Room was average. Breakfast was a joke, no name cereal and coffee " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Waleed $57 nightly $63 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Travelodge-By-Wyndham-Florence.h528148.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-10&endDate=2026-04-11®ionId=3000353197&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPamplico-Hotels.d3000353197.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPamplico-Hotels.d3000353197.Travel-Guide-Hotels) ## Top Pamplico Hotel Reviews ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg) ### Hyatt Place Florence Downtown 6/10 Okay "Everything was great except the staff at the bar. The first girl didn’t know how to use a bottle opener to open a beer. I asked the second girl to put in a grilled cheese right away so I can bring it up to my 1 year old baby. It took about an hour to get this grilled cheese and it came out with the rest of my food. I was given no bag to carry my several boxes of food. The grilled cheese fell on the ground and the bartender would not take the 7 dollars off of my bill. Horrible bar service. " [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 10/10 Excellent "Great" [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![SpringHill Suites by Marriott Florence](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c_y.jpg) ### SpringHill Suites by Marriott Florence 10/10 Excellent "Second time staying here! Love it, bathroom needs a lit bit love but is okay! " [](https://expedia.com/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 8/10 Good "Stay was good. Staff was great. A problem with the drain in the bathroom but they were very nice about it " [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Comfort Suites Florence I-95](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4_y.jpg) ### Comfort Suites Florence I-95 10/10 Excellent "Very clean and well cared for property. Staff is so nice and friendly " [](https://expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 8/10 Good "Property was acceptable for our standards." [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c_y.jpg) ### Microtel Inn & Suites by Wyndham Florence 8/10 Good "Not sure about pet friendly didn’t have one" [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "Employees were very helpful and friendly. Great stay!" [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Fairfield Inn & Suites by Marriott Florence I-20](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640_y.jpg) ### Fairfield Inn & Suites by Marriott Florence I-20 10/10 Excellent "The room was clean and tidy. Very nice staff and the breakfast in the morning was very good." [](https://expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ## More cheap stays in Pamplico ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Florence 1912 Enterprise Dr Florence SC $60 nightly $67 total Mar 29 - Mar 30 Total with taxes and fees 6.8/10 (1,002 reviews) [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Howard Johnson by Wyndham Florence 2038 W Lucas Street Florence SC $60 nightly $68 total Apr 26 - Apr 27 Total with taxes and fees 8.6/10 Excellent! (2,600 reviews) [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Florence/I-95 North 2111 West Lucas St/I-95 Florence SC $61 nightly $69 total Apr 7 - Apr 8 Total with taxes and fees 6.8/10 (1,002 reviews) [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr Florence SC $87 nightly $97 total Apr 26 - Apr 27 Total with taxes and fees 8.8/10 Excellent! (36 reviews) [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Florence Center Area 527 Woody Jones Blvd Florence SC $102 nightly $114 total Apr 26 - Apr 27 Total with taxes and fees 9/10 Wonderful! (1,237 reviews) [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/ffaddd2a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 2101 Florence Harllee Blvd Florence SC $127 nightly $142 total Apr 5 - Apr 6 Total with taxes and fees 8.6/10 Excellent! (1,003 reviews) [](https://expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ## Hotels in Pamplico with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-Pamplico-Hotels.s40-0-d3000353197.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 13 properties [](https://expedia.com/3Star-Pamplico-Hotels.s30-0-d3000353197.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 61 properties [](https://expedia.com/2Star-Pamplico-Hotels.s20-0-d3000353197.Travel-Guide-Filter-Hotels) ## Find out more about Pamplico ### Top reasons to visit Pamplico - **Outdoor Adventures:** Pamplico is ideal for outdoor lovers, featuring parks and fairgrounds perfect for family activities. - **Cultural Experiences:** Dive into the local history and community culture through museums and charming neighborhoods. - **Golfing Opportunities:** Enjoy a round of golf at local courses, adding a sporty twist to your vacation. - **Family-Friendly Atmosphere:** The city offers a variety of attractions suitable for all ages, ensuring fun for the whole family. - **Affordable Accommodations:** Find budget-friendly hotels and cozy bed & breakfasts for a comfortable stay. ### Find great hotels near Pamplico Explore a variety of accommodation options in Pamplico, South Carolina, where you'll find budget-friendly hotels and charming bed & breakfasts. Whether you're traveling for business or leisure, Pamplico offers pet-friendly and LGBTQIA welcoming options to ensure a comfortable stay. Discover cheap apartments, rentals, and housing near Pamplico to suit your needs, making your visit both enjoyable and convenient. - **[Hyatt Place Florence Downtown: ](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information)** Situated 18 miles from Pamplico, this 3-star hotel boasts a remarkable guest rating of 9.0\. Hyatt Place Florence Downtown features a modern and inviting atmosphere, ideal for both business and leisure travelers. The hotel is pet-friendly, welcoming your furry companions with amenities tailored to ensure comfort. With spacious rooms equipped with contemporary conveniences and a focus on customer service, you'll find a pleasant stay enriched by an array of business facilities, making it perfect for work trips as well. - **[The Inn at the Crossroads: ](https://www.expedia.com/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information)** Located just 14 miles from Pamplico, The Inn at the Crossroads is a budget-friendly lodging option with an impressive guest rating of 9.4\. This charming inn provides a cozy and welcoming environment that caters primarily to business travelers. Its strategic location offers easy access to local attractions and amenities, ensuring you can balance work and relaxation seamlessly. Guests appreciate the attentive service and comfortable accommodations that make this inn a delightful choice for an affordable stay. - **[Quality Inn Mullins - Marion: ](https://www.expedia.com/Florence-Hotels-Quality-Inn.h24816.Hotel-Information)** Positioned 19 miles from Pamplico, Quality Inn Mullins - Marion is another budget-friendly option that welcomes both guests and their pets, making it a great choice for animal lovers. With a guest rating that reflects its value, this hotel provides essential amenities for a comfortable stay. Enjoy the convenience of modern features and a relaxed atmosphere, ensuring that your time away from home is both enjoyable and accommodating for you and your furry friends. ### Where to stay near Pamplico Pamplico, South Carolina, offers a delightful blend of outdoor adventures and family-friendly attractions. Explore the charming neighborhoods and discover budget-friendly rentals perfect for your stay. Enjoy the inviting atmosphere while visiting nearby cities, where trendy cafes and relaxing parks await. Whether you're soaking up the local culture or indulging in family activities, Pamplico is an ideal destination for creating unforgettable memories with loved ones. - **[Gresham: ](https://www.expedia.com/Gresham-Hotels.d3000455952.Travel-Guide-Hotels)** Located 10 miles from Pamplico, Gresham is a charming city that offers a blend of outdoor activities and family-friendly experiences. With visitor numbers peaking from May to July, it's a great destination for those looking to enjoy the warmer months. Gresham boasts a variety of recreational areas and parks, perfect for picnics, golfing, and leisurely strolls. Notable nearby attractions include beautiful beaches, serene lakes, and urban parks, making it an ideal spot for romantic getaways or family adventures. - **[Coward: ](https://www.expedia.com/Coward-Hotels.d3000353109.Travel-Guide-Hotels)** Also situated 10 miles from Pamplico, Coward is a vibrant city known for its scenic beauty and sporting activities. The peak travel season occurs from July to August and December, attracting visitors eager to experience the great outdoors. Coward is particularly well-regarded for its golf courses and motor racing events, offering thrilling experiences for sports enthusiasts. Nearby landmarks like national state parks, lakes, and marinas provide ample opportunities for exploration and relaxation amidst nature. - **[Effingham: ](https://www.expedia.com/Effingham-Hotels.d553248635975849973.Travel-Guide-Hotels)** Just 11 miles from Pamplico, Effingham is a delightful city that draws visitors year-round for its outdoor and family-oriented attractions. With peak visits from June to July and September, Effingham is perfect for those seeking fun-filled experiences. The city features an arena entertainment facility, a boardwalk, and a water park, catering to thrill-seekers and families alike. Nearby, you can discover picturesque lakes, a bustling tourist precinct, and esplanades that offer scenic views and leisurely strolls. ### Things to do in Pamplico Pamplico, South Carolina, is perfect for outdoor family vacations, offering a variety of activities. Visitors can enjoy a round of golf at local courses, indulge in shopping at nearby centers, and explore the charming city atmosphere. Whether you're looking for relaxation or adventure, Pamplico has something for everyone to create lasting memories. **Shopping** Pamplico offers charming local shops for unique gifts and souvenirs. If you're up for a drive, visit Florence Mall, about 15 miles away, featuring a variety of stores from national retailers to local boutiques. You'll find plenty of options to bring home a piece of South Carolina. **Recreation** Pamplico Wellness Center offers rejuvenating spa treatments and yoga classes in a tranquil environment, perfect for relaxation. For outdoor enthusiasts, explore the nearby Pee Dee River for fishing and kayaking, or enjoy a leisurely stroll at the local parks, surrounded by lush landscapes and charming southern scenery. **Adventure** Explore the scenic beauty of Lynches River County Park, where you can kayak or canoe along the tranquil waters and enjoy birdwatching. For a thrilling experience, head to the nearby Pee Dee River for fishing and tubing, immersing yourself in the local outdoor adventure. **Nightlife** Explore the vibrant nightlife at The Pub on Main Street, where you can enjoy karaoke nights and a selection of local brews. For a laid-back vibe, visit The Corner Bar for signature cocktails and live acoustic performances from local artists. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Pamplico - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Pamplico are January to February and November, where the prices are slightly lower. This is in comparison to April and August to September, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Pamplico is Monday. The most expensive day to stay in Pamplico is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels currently available. To find the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your Pamplico hotel reservation with your flights and activities through an Expedia package deal. ### Find the best attractions near Pamplico Pamplico, South Carolina, is perfect for outdoor enthusiasts and families seeking city-themed vacations. You can explore a variety of attractions, including fairgrounds, parks, and museums that cater to those looking for outdoor adventures and cultural experiences. Whether you're enjoying the local fare or immersing yourself in the community's rich history, Pamplico offers a memorable getaway for all types of travelers. - **[Eastern Carolina Agricultural Fairgrounds: ](https://www.expedia.com/Eastern-Carolina-Agricultural-Fairgrounds-Hotels.0-l6162140-0.Travel-Guide-Filter-Hotels)** Located 14 miles from Pamplico, this fairground offers a vibrant atmosphere for families with various events throughout the year. Enjoy thrilling rides, delicious fair food, and local agricultural exhibits, making it a perfect spot for a fun-filled day. - **[Lions Park: ](https://www.expedia.com/Lions-Park-Hotels.0-l553248621560871592-0.Travel-Guide-Filter-Hotels)** Situated 13 miles away, Lions Park is an eco-friendly retreat that features lush greenery and family-friendly amenities. It’s an ideal place for picnics, walking trails, and enjoying nature, providing a peaceful escape for outdoor enthusiasts. - **[Ronald E. McNair Life History Center: ](https://www.expedia.com/Ronald-E-McNair-Life-History-Center-Hotels.0-l553248621560871590-0.Travel-Guide-Filter-Hotels)** Also 14 miles from Pamplico, this museum celebrates the life of astronaut Ronald McNair. Explore fascinating exhibits that highlight his achievements and contributions to science and education, offering a rich cultural experience. ### Best time to go to Pamplico The best time to visit Pamplico is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 46.0°F (7.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 50.0°F (10.0°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 55.8°F (13.2°C) | Light Rain | Mostly Sunny | Average | Average | | April | 63.7°F (17.6°C) | Light Rain | Mostly Sunny | Moderately High | Slightly High | | May | 71.2°F (21.8°C) | Light Rain | Mostly Sunny | Average | Average | | June | 78.1°F (25.6°C) | Light Rain | Mostly Sunny | Average | Average | | July | 81.0°F (27.2°C) | Light Rain | Mostly Sunny | Moderately High | Average | | August | 79.3°F (26.3°C) | Light Rain | Mostly Sunny | Moderately High | Slightly High | | September | 74.7°F (23.7°C) | Light Rain | Mostly Sunny | Average | Slightly High | | October | 65.5°F (18.6°C) | Light Rain | Mostly Sunny | Average | Average | | November | 55.0°F (12.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 50.0°F (10.0°C) | Light Rain | Mostly Sunny | Average | Average | ### The nearest major airports for your trip to Pamplico If you're traveling to Pamplico, South Carolina, you have several airport options. Charleston International Airport ([CHS](https://www.expedia.com/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels)) is 81 miles away, with nearby hotels like [The Charleston Place](https://www.expedia.com/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information), [Hotel Bennett](https://www.expedia.com/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information), and [The Dewberry Charleston](https://www.expedia.com/Charleston-Hotels-The-Dewberry-Charleston.h12880056.Hotel-Information), all offering transfer services. [MYR](https://www.expedia.com/Myrtle-Beach-Intl-Airport-Hotels.0-aMYR-0.Travel-Guide-Filter-Hotels)tle Beach International Airport (MYR) is closer at 43 miles, with accommodations such as Hilton Grand Vacations Club Ocean Enclave and [DoubleTree Resort by Hilton Myrtle Beach Oceanfront](https://www.expedia.com/Myrtle-Beach-Hotels-DoubleTree-Resort-By-Hilton-Myrtle-Beach.h845521.Hotel-Information), both providing easy airport access. W[ILM](https://www.expedia.com/Wilmington-Intl-Airport-Hotels.0-aILM-0.Travel-Guide-Filter-Hotels)ington International Airport (ILM), located 97 miles from Pamplico, features hotels like [Hotel Ballast Wilmington](https://www.expedia.com/Wilmington-Hotels-Hotel-Ballast-Wilmington.h13731.Hotel-Information) and [ARRIVE Wilmington](https://www.expedia.com/Wilmington-Hotels-ARRIVE-Wilmington.h8218879.Hotel-Information), also conveniently accessible from the airport. Each of these airports offers a range of travel options to make your visit enjoyable. ## Frequently asked questions ### What is the best area to stay in Pamplico? > This central area offers convenient access to the town's limited amenities and serves as the main hub for local activity. You'll find the town hall, local shops, and a few eateries concentrated here, making it easy to navigate on foot. > > > For travelers seeking a quiet and convenient base for exploring the surrounding rural landscape, staying near the town center is ideal. ### When is the best time to go to Pamplico? > During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat and humidity of summer or the cooler temperatures of winter. Travelers who prioritize comfortable weather for their trips will find these months most appealing. > > > Couples looking for a relaxed getaway will appreciate the pleasant conditions that allow for leisurely strolls through the town and surrounding countryside. The moderate temperatures create a friendly space for dining outdoors or simply enjoying the quiet pace of life in Pamplico. > > > Families traveling with children will also find these seasons beneficial. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Pamplico hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Pamplico hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Myrtle Beach Hotels ](https://www.expedia.com/Myrtle-Beach-Hotels.d601685.Travel-Guide-Hotels) - [Gresham Hotels ](https://www.expedia.com/Gresham-Hotels.d3000455952.Travel-Guide-Hotels) - [Coward Hotels ](https://www.expedia.com/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [Rv Parks in Gresham ](https://www.expedia.com/Gresham-RV-Parks.d3000455952-aaRVParks.Travel-Guide-Accommodation) - [Motels in Gresham ](https://www.expedia.com/Gresham-Motels.d3000455952-aaMotels.Travel-Guide-Accommodation) - [3 Star Hotels in Gresham ](https://www.expedia.com/3Star-Gresham-Hotels.s30-0-d3000455952.Travel-Guide-Filter-Hotels) - [Vacation Homes in Gresham ](https://www.expedia.com/Gresham-Private-Vacation-Homes.d3000455952-aaPrivateVacationHomes.Travel-Guide-Accommodation) - 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