Beginning of main content

Isle of Palms Hotel Rooms at the Independent

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Isle of Palms Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.

Featured Isle of Palms Independent Hotels

See all 144 Hotels in Isle of Palms
Seaside Inn Oceanfront

Seaside Inn Oceanfront

1004 Ocean Blvd, Isle Of Palms
2.5 out of 5.0
3.2 out of 5 (369 reviews)
Good view. Musty smelling rooms though. The updated the place but the room had a strong musty smell to it. Free breakfast was ok - actually … - 



Recently booked Isle of Palms hotels

Seaside Inn Oceanfront
2.5 out of 5.0
Last booking: 4 hours ago
Wild Dunes Resort By Destination Hotels
4.0 out of 5.0
Last booking: 5 hours ago

Independent Isle of Palms Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Isle of Palms, Charleston. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Isle of Palms hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Isle of Palms Independent locations may even offer extra little benefits and discounts for frequent travelers.