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Find spa resorts & hotels in Medical Center District, San Antonio from $100

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Top Medical Center District Resorts & Hotels with Spas

Embassy Suites by Hilton San Antonio Brooks Hotel & Spa

3.5 star property
9.2 out of 10, Wonderful, (1004)
"Great hotel!! Very clean Great staff!!! Will definitely stay here again "
$144 nightly
The price is $170
Sep 7 - Sep 8
Total with taxes and fees
Embassy Suites by Hilton San Antonio Brooks Hotel & Spa

Hotel Contessa

4.0 star property
9.0 out of 10, Wonderful, (3217)
"Great place and location "
$144 nightly
The price is $171
Sep 1 - Sep 2
Total with taxes and fees
Hotel Contessa

Holiday Inn Express San Antonio Rivercenter Area by IHG

2.5 star property
8.8 out of 10, Excellent, (1002)
"The room was clean and cozy, would love to stay with them again!"
$86 nightly
The price is $100
Sep 14 - Sep 15
Total with taxes and fees
Holiday Inn Express San Antonio Rivercenter Area by IHG

Hyatt Regency San Antonio Riverwalk

4.0 star property
9.2 out of 10, Wonderful, (1794)
"We love and enjoyed our stay!"
$164 nightly
The price is $194
Sep 1 - Sep 2
Total with taxes and fees
Hyatt Regency San Antonio Riverwalk

Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort

4.5 star property
8.6 out of 10, Excellent, (1007)
"Very nice place. "
$154 nightly
The price is $182
Sep 1 - Sep 2
Total with taxes and fees
Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort

Hotel Valencia Riverwalk

4.5 star property
9.4 out of 10, Exceptional, (1992)
"It was a great stay! Best hotel we've stayed at in San Antonio. "
$183 nightly
The price is $215
Sep 1 - Sep 2
Total with taxes and fees
Hotel Valencia Riverwalk

Kimpton Santo San Antonio - Riverwalk by IHG

4.5 star property
9.2 out of 10, Wonderful, (467)
"Amazing stay!"
$197 nightly
The price is $233
Sep 2 - Sep 3
Total with taxes and fees
Kimpton Santo San Antonio - Riverwalk by IHG

Mokara Hotel & Spa San Antonio

4.5 star property
9.6 out of 10, Exceptional, (1008)
"Excellent location and great services "
$191 nightly
The price is $223
Sep 23 - Sep 24
Total with taxes and fees
Mokara Hotel & Spa San Antonio

Thompson San Antonio - Riverwalk, by Hyatt

5.0 star property
9.0 out of 10, Wonderful, (838)
"Great hotel"
$223 nightly
The price is $264
Aug 31 - Sep 1
Total with taxes and fees
Thompson San Antonio - Riverwalk, by Hyatt

Omni La Mansion del Rio

4.0 star property
9.4 out of 10, Exceptional, (2704)
"Beautiful hotel, great location to all dining and shopping."
$166 nightly
The price is $196
Sep 29 - Sep 30
Total with taxes and fees
Omni La Mansion del Rio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Medical Center District Hotel Reviews

Find out more about Medical Center District

Find out more about Medical Center District

Top Medical Center District attractions for a relaxing vacation

In the heart of the Medical Center District, travelers seeking rejuvenation will find not only luxurious spa hotels but also a wealth of activities that enhance their stay. Explore the serene beauty of the nearby Hermann Park, where you can unwind with a leisurely stroll or a family picnic, all while enjoying the picturesque landscapes and the iconic McGovern Centennial Gardens. For those interested in wellness, the Texas Medical Center offers informative health-focused tours that can inspire and educate about the latest in medical advancements. Just a short drive away, the Houston Museum District invites you to delve into art and culture, with renowned institutions like the Museum of Fine Arts and the Houston Museum of Natural Science, perfect for a family outing after a morning at the spa. Enjoy a culinary adventure at the vibrant Rice Village, where you can savor exquisite dining options that cater to all tastes, ensuring a delightful evening after a day of pampering. Finally, wind down your day at a local rooftop bar that offers stunning views of the Houston skyline, creating the perfect backdrop for relaxation after a day filled with exploration. Staying at spa hotels in this neighborhood means indulging in top amenities like luxurious spa treatments, attentive service, and spacious rooms designed for comfort, all while being strategically located to enjoy the area's unique offerings.

Frequently asked questions

Looking for a spa hotel in Medical Center District?
Forget the stress of everyday life and book yourself a lush spa hotel. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your holiday.
What's there to see and do in Medical Center District?
Enjoy all that Medical Center District has to offer and visit USAA Corporate Office Headquarters, Cinemark San Antonio 16, and The San Antonio Art Institute. If you have extra time while you're in the area, you might want to see Six Flags Fiesta Texas and Lackland Air Force Base.
What is a Medical Center District spa hotel?
Spa hotels in Medical Center District provide lodging and have an on-site spa which offers services including massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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