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Santa Cruz Vacation Rentals

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Our top choices for Santa Cruz vacation rentals

1. Segovia Studio Units

Segovia Studio Units
3.0 star property
Sabana Abajo
8.6 out of 10, Excellent, (922 reviews)
"Great place to stay"
United States
Lanoris
$88 nightly
The price is $94
Oct 5 - Oct 6
Total with taxes and fees
Segovia Studio Units

2. Casa Las Ruinas Boutique Hotel

Casa Las Ruinas Boutique Hotel
4.0 star property
Old San Juan
8.4 out of 10, Very Good, (433 reviews)
"It was beautiful, location was perfect and staff was amazing"
United States
jailanie
$95 nightly
The price is $103
Sep 20 - Sep 21
Total with taxes and fees
Casa Las Ruinas Boutique Hotel

3. La Mona Loiza Apartments Complex

La Mona Loiza Apartments Complex
3.0 star property
Santurce
8.6 out of 10, Excellent, (675 reviews)
"My favorite go to stay!"
United States
Jared
$85 nightly
The price is $93
Sep 8 - Sep 9
Total with taxes and fees
La Mona Loiza Apartments Complex

4. ESJ Beach Hotel

ESJ Beach Hotel
3.5 star property
Isla Verde
6.8 out of 10, (4,571 reviews)
"Recommend staying here for a nice & economic stay!"
United States
Johnny
$217 nightly
The price is $236
Sep 7 - Sep 8
Total with taxes and fees
ESJ Beach Hotel

5. Castellana by Otium

Castellana by Otium
2.5 star property
Sabana Abajo
9.0 out of 10, Wonderful, (10 reviews)
"The place was easy to get to and so close to the airport and Old San Juan. The area is safe and quiet. Will definitely book there again."
United States
KATHLEEN J
$199 nightly
The price is $217
Sep 9 - Sep 10
Total with taxes and fees
Castellana by Otium

6. MANSION MIRAFLORES

MANSION MIRAFLORES
3.5 star property
Santurce
9.4 out of 10, Exceptional, (270 reviews)
"Great little place. I thought I booked with a hotel but my one night stay was great."
United States
Emma
$134 nightly
The price is $146
Oct 6 - Oct 7
Total with taxes and fees
MANSION MIRAFLORES

7. Mare 1660

Mare 1660
3.0 star property
Isla Verde
8.6 out of 10, Excellent, (114 reviews)
"Great stay! Near so many things to do. And beautiful view from this unit."
United States
Francillia
$201 nightly
The price is $219
Sep 8 - Sep 9
Total with taxes and fees
Mare 1660

8. La Ferreteria Apartments

La Ferreteria Apartments
3.0 star property
Puerta de Tierra
8.8 out of 10, Excellent, (630 reviews)
"Good location for various places in PR."
United States
Natalia
$123 nightly
The price is $134
Sep 7 - Sep 8
Total with taxes and fees
La Ferreteria Apartments

9. Villas at Auxilio Mutuo 104

Villas at Auxilio Mutuo 104
3.0 star property
Universidad
8.0 out of 10, Very Good, (34 reviews)
"Quiet and safe villa, rooms were clean and beds were comfy."
United States
Jorge
$161 nightly
The price is $175
Sep 18 - Sep 19
Total with taxes and fees
Villas at Auxilio Mutuo 104

10. Mare 1562

Mare 1562
3.0 star property
Isla Verde
9.0 out of 10, Wonderful, (107 reviews)
"Clean room, ocean view of sunrise, beach access, close to everything"
United States
Maria E
$190 nightly
The price is $207
Sep 7 - Sep 8
Total with taxes and fees
Mare 1562

11. Patio Elba Boutique Hotel

Patio Elba Boutique Hotel
4.0 star property
Santurce
9.2 out of 10, Wonderful, (319 reviews)
"Excellent service!!"
United States
Isaac Daniel
$175 nightly
The price is $191
Sep 7 - Sep 8
Total with taxes and fees
Patio Elba Boutique Hotel

12. Numero Uno Beach Apartments

Numero Uno Beach Apartments
3.0 star property
Santurce
8.8 out of 10, Excellent, (60 reviews)
"I cannot wait to return. Toes in the sand, delicious food and drinks, and lovely hosts who make you feel so spoiled. My ocean view room was very clean! Note: the restaurant and reception area are not air conditioned. But the beach breeze was strong enough to make things pleasant and blow away any insects. Clear, warm water and a chill vibe."
United States
Jane
$214 nightly
The price is $229
Sep 14 - Sep 15
Total with taxes and fees
Numero Uno Beach Apartments

13. 609 Condado Ave

609 Condado Ave
2.0 star property
Santurce
10.0 out of 10, Exceptional, (2 reviews)
"It was a nice hotel and everything was near by I loved it and will stay again"
United States
Vladimir
$159 nightly
The price is $174
Sep 28 - Sep 29
Total with taxes and fees
609 Condado Ave

14. Hugo's Rental

Hugo's Rental
5.0 star property
Old San Juan
9.2 out of 10, Wonderful, (341 reviews)
"The room was exactly how it’s described. The location was great. In walking distance to food, small markets and gift shop. We stayed for one night before our cruise. Cruise port was less than 10 minutes away. Would stay again."
United States
Debbie
$170 nightly
The price is $197
Oct 6 - Oct 7
Total with taxes and fees
Hugo's Rental

15. Nando's Place

Nando's Place
3.5 star property
Puerta de Tierra
8.0 out of 10, Very Good, (76 reviews)
"Cool place to stay for the weekend"
United States
Azucena
$111 nightly
The price is $121
Sep 21 - Sep 22
Total with taxes and fees
Nando's Place

16. VERDE by DW

VERDE by DW
3.5 star property
Santurce
9.2 out of 10, Wonderful, (41 reviews)
"Beautiful Place!"
Canada
Agustina
$230 nightly
The price is $250
Sep 7 - Sep 8
Total with taxes and fees
VERDE by DW

17. Casa Costera, Isla Verde Beach, Apartments by Marriott Bonvoy

Casa Costera, Isla Verde Beach, Apartments by Marriott Bonvoy
4.0 star property
Isla Verde
9.0 out of 10, Wonderful, (239 reviews)
"Very clean room, sweet staff and close to the beach."
United States
Seanna
$202 nightly
The price is $220
Sep 27 - Sep 28
Total with taxes and fees
Casa Costera, Isla Verde Beach, Apartments by Marriott Bonvoy

18. ROSA by DW

ROSA by DW
3.5 star property
Santurce
9.6 out of 10, Exceptional, (25 reviews)
"Place was awesome! So well decorated and appointed. The most stylish place I’ve been to!"
United States
joseph
$245 nightly
The price is $267
Sep 7 - Sep 8
Total with taxes and fees
ROSA by DW

19. DUNA by DW

DUNA by DW
3.5 star property
Santurce
9.4 out of 10, Exceptional, (92 reviews)
"Our stay was an absolute dream! The apartment complex was a perfect blend of modern comfort with a lush, tropical atmosphere. The vibrant property, we highly recommend this slice of paradise for an authentic and relaxing getaway"
United States
Kiana
$245 nightly
The price is $260
Sep 7 - Sep 8
Total with taxes and fees
DUNA by DW

20. Colmado by Otium

Colmado by Otium
3.0 star property
Zarzal
$293 nightly
The price is $294
Sep 7 - Sep 8
Total with taxes and fees
Colmado by Otium
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $93 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we have vacation rentals near well known points of interest in Santa Cruz, or you can go with a more remote option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Santa Cruz has to offer?

1120 Vieques by Stay with Bear: This vacation home rental near Santa Cruz is near the airport and equipped with air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop, and a microwave.

What can I see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Carabali Rainforest Park, or get outside and enjoy nature at Luquillo Beach. Other popular places to visit in the area include Port of San Juan and El Yunque National Forest.

What are vacation rentals like in Santa Cruz?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Santa Cruz. Vacation rentals feature amenities such as laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and bustling concierge desks while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive option for a family trip or a small group gathering.